Loss of DGKζ and Cbl-b results in a greater percentage of splenic CD8+ T cells with an activated phenotype. Loss of DGKζ and Cbl-b results in a greater.

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Loss of DGKζ and Cbl-b results in a greater percentage of splenic CD8+ T cells with an activated phenotype. Loss of DGKζ and Cbl-b results in a greater percentage of splenic CD8+ T cells with an activated phenotype. (A) Thymocytes, (B) splenocytes, and lymph node cells from WT and KO mice were stained for cell surface markers CD8 and CD4. Percentage and absolute number were determined for different cell populations. (C) Splenocytes were stained for CD8, CD4, CD44, and CD62L, and the percentage and absolute number of CD8+CD44hi cells were determined. *p < 0.05, **p < 0.01, ***p < 0.001. ns, not significant. Erin M. Wesley et al. ImmunoHorizons 2018;2:107-118 Copyright © 2018 The Authors