Surgical Lung Biopsy in Adult Respiratory Distress Syndrome: A Meta-Analysis Laura J. Libby, MD, Brian D. Gelbman, MD, Nasser K. Altorki, MD, Paul J.

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Surgical Lung Biopsy in Adult Respiratory Distress Syndrome: A Meta-Analysis Laura J. Libby, MD, Brian D. Gelbman, MD, Nasser K. Altorki, MD, Paul J. Christos, DPH, MS, Daniel M. Libby, MD The Annals of Thoracic Surgery Volume 98, Issue 4, Pages 1254-1260 (October 2014) DOI: 10.1016/j.athoracsur.2014.05.029 Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Meta-analysis flow chart. The Annals of Thoracic Surgery 2014 98, 1254-1260DOI: (10.1016/j.athoracsur.2014.05.029) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Forrest plots for the pooled data. (A) Forest plot for specific diagnosis made in patients who underwent open lung biopsy (OLB). (B) Forest plot of pooled change in management rate of patients who underwent OLB. (C) Forest plot of pooled in-hospital mortality rate. (D) Forest plot of pooled surgical complication rate of OLB. The solid squares denote the mean difference and are proportional to weights used in meta-analysis. The dashed line indicates the summary measure, with the associated diamond denoted the weighted mean difference and the lateral tips of the diamond indicating the associated confidence intervals The horizontal lines represent the 95% confidence intervals. The Annals of Thoracic Surgery 2014 98, 1254-1260DOI: (10.1016/j.athoracsur.2014.05.029) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Pathologic diagnoses made by open lung biopsy. (LAM = lymphangioleiomyomatosis.) The Annals of Thoracic Surgery 2014 98, 1254-1260DOI: (10.1016/j.athoracsur.2014.05.029) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Complications associated with open lung biopsy. The Annals of Thoracic Surgery 2014 98, 1254-1260DOI: (10.1016/j.athoracsur.2014.05.029) Copyright © 2014 The Society of Thoracic Surgeons Terms and Conditions