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Beating-Heart Versus Conventional On-Pump Coronary Artery Bypass Grafting: A Meta- Analysis of Clinical Outcomes  Umar A.R. Chaudhry, MBBS, Leanne Harling,

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Presentation on theme: "Beating-Heart Versus Conventional On-Pump Coronary Artery Bypass Grafting: A Meta- Analysis of Clinical Outcomes  Umar A.R. Chaudhry, MBBS, Leanne Harling,"— Presentation transcript:

1 Beating-Heart Versus Conventional On-Pump Coronary Artery Bypass Grafting: A Meta- Analysis of Clinical Outcomes  Umar A.R. Chaudhry, MBBS, Leanne Harling, MRCS, PhD, Amir H. Sepehripour, MRCS, George Stavridis, MD, John Kokotsakis, MD, Hutan Ashrafian, MRCS, PhD, Thanos Athanasiou, FRCS, PhD  The Annals of Thoracic Surgery  Volume 100, Issue 6, Pages (December 2015) DOI: /j.athoracsur Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Search strategy. (BH-ONCAB = beating-heart on-pump coronary artery bypass grafting; ONCAB = on-pump coronary artery bypass grafting.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Forest plots demonstrate primary outcomes for beating-heart on-pump coronary artery bypass grafting (BH-ONCAB) vs conventional on-pump coronary artery bypass grafting (C-ONCAB) for (a) early mortality and (b) midterm mortality. The squares indicate the mean difference and are proportional to the weights used in the meta-analysis. The vertical line indicates no effect. The diamond indicates the pooled summary statistic (odds ratio or hazard ratio), and the lateral tips of the diamond indicate the associated confidence intervals (CI). The horizontal lines represent the 95% CI. (IV = inverse variance; M-H: Mantel-Haenszel.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Forest plots demonstrate secondary outcomes for beating-heart on-pump coronary artery bypass grafting (BH-ONCAB) vs conventional on-pump coronary artery bypass grafting (C-ONCAB) for (a) cerebrovascular disease, (b) renal failure, and (c) myocardial infarction. The squares indicate the mean difference and are proportional to the weights used in the meta-analysis. The vertical line indicates no effect. The diamond indicates the summary statistic (odds ratio), and the lateral tips of the diamond indicate the associated confidence intervals (CI). The horizontal lines represent the 95% CI. (M-H: Mantel-Haenszel.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 (a) Risk of bias assessment. (b) Funnel plot for early mortality for beating-heart on-pump coronary artery bypass grafting vs conventional on-pump coronary artery bypass grafting. (OR = odds ratio; SE = standard error.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

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