Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction  F.M. Radtke,

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Presentation transcript:

Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction  F.M. Radtke, M. Franck, J. Lendner, S. Krüger, K.D. Wernecke, C.D. Spies  British Journal of Anaesthesia  Volume 110, Pages i98-i105 (June 2013) DOI: 10.1093/bja/aet055 Copyright © 2013 The Author(s) Terms and Conditions

Fig 1 Screening, randomization, and the follow-up. British Journal of Anaesthesia 2013 110, i98-i105DOI: (10.1093/bja/aet055) Copyright © 2013 The Author(s) Terms and Conditions

Fig 2 Comparison of patients with and without postoperative delirium (multivariate analysis). MMSE, Mini-Mental State Examination. Multiple logistic regression with delirium as response was conducted in order to confirm the results multivariately with BIS open vs blinded, age, MMSE values, duration of surgery, ASA physical status, and % BIS<20 as variables. British Journal of Anaesthesia 2013 110, i98-i105DOI: (10.1093/bja/aet055) Copyright © 2013 The Author(s) Terms and Conditions

Fig 3 Multivariate analysis of mortality after 3 months. ASA PS, American Society of Anesthesiologists physical status. Multiple logistic regression with mortality at 3 months as response was conducted with BIS open vs blinded, age, MMSE values, duration of surgery, ASA physical status, delirium, and % BIS<20 as variables. British Journal of Anaesthesia 2013 110, i98-i105DOI: (10.1093/bja/aet055) Copyright © 2013 The Author(s) Terms and Conditions