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Cognitive function after sevoflurane- vs propofol-based anaesthesia for on-pump cardiac surgery: a randomized controlled trial  J. Schoen, L. Husemann,

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Presentation on theme: "Cognitive function after sevoflurane- vs propofol-based anaesthesia for on-pump cardiac surgery: a randomized controlled trial  J. Schoen, L. Husemann,"— Presentation transcript:

1 Cognitive function after sevoflurane- vs propofol-based anaesthesia for on-pump cardiac surgery: a randomized controlled trial  J. Schoen, L. Husemann, C. Tiemeyer, A. Lueloh, B. Sedemund-Adib, K.-U. Berger, M. Hueppe, M. Heringlake  British Journal of Anaesthesia  Volume 106, Issue 6, Pages (June 2011) DOI: /bja/aer091 Copyright © 2011 The Author(s) Terms and Conditions

2 Fig 1 Flow chart of patient recruitment and reasons for exclusion from the analysis of patients after a sevoflurane- or propofol-based anaesthesia during on-pump cardiac surgery. British Journal of Anaesthesia  , DOI: ( /bja/aer091) Copyright © 2011 The Author(s) Terms and Conditions

3 Fig 2 Results of the cognitive tests in patients after a sevoflurane- or propofol-based anaesthesia during on-pump cardiac surgery in patients with and without cerebral desaturation. (a) AMT. Means and standard error of the mean. (b) Stroop Test. Means and standard error of the mean. (c) TMT. Means and standard error of the mean. (d) Word List. Means and standard error of the mean. AMT, Abbreviated Mental Test; POD, postoperative day; TMT, trail-making-test; WL-N, Word List. British Journal of Anaesthesia  , DOI: ( /bja/aer091) Copyright © 2011 The Author(s) Terms and Conditions

4 Fig 3 Course of markers of organ function in patients after a sevoflurane- or propofol-based anaesthesia during on-pump cardiac surgery in patients with and without cerebral desaturation. (a) Creatinine. Means and standard error of the mean. (b) Troponin T. Means and standard error of the mean. (c) S100-β. Means and standard error of the mean. (d) C-reactive protein. Means and standard error of the mean. British Journal of Anaesthesia  , DOI: ( /bja/aer091) Copyright © 2011 The Author(s) Terms and Conditions

5 Fig 4 Proportion of patients with no versus one or more major organ complications in the postoperative course. British Journal of Anaesthesia  , DOI: ( /bja/aer091) Copyright © 2011 The Author(s) Terms and Conditions


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