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Evaluation of a novel closed-loop total intravenous anaesthesia drug delivery system: a randomized controlled trial  T.M. Hemmerling, E. Arbeid, M. Wehbe,

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Presentation on theme: "Evaluation of a novel closed-loop total intravenous anaesthesia drug delivery system: a randomized controlled trial  T.M. Hemmerling, E. Arbeid, M. Wehbe,"— Presentation transcript:

1 Evaluation of a novel closed-loop total intravenous anaesthesia drug delivery system: a randomized controlled trial  T.M. Hemmerling, E. Arbeid, M. Wehbe, S. Cyr, R. Taddei, C. Zaouter  British Journal of Anaesthesia  Volume 110, Issue 6, Pages (June 2013) DOI: /bja/aet001 Copyright © 2013 The Author(s) Terms and Conditions

2 Fig 1 Flowchart of the trial.
British Journal of Anaesthesia  , DOI: ( /bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

3 Fig 2 McSleepy user's interface for set up. Columns from left to right: input of patient data; input of anaesthesia and surgery-relevant data; start buttons for anaesthetic drugs including choice of two different neuromuscular blocking drugs; start button for induction of anaesthesia. British Journal of Anaesthesia  , DOI: ( /bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

4 Fig 3 Flow chart showing the induction phase of the McSleepy group.
British Journal of Anaesthesia  , DOI: ( /bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

5 Fig 4 The control of depth of hypnosis as a percentage of the time of duration of anaesthesia. The performance is defined as ‘excellent', ‘good', ‘poor', and ‘inadequate', when the BIS is ≤10%, 11–20%, 21–30%, or >30% of the target BIS value, respectively. Data are presented as n, mean (sd). #P<0.05, *P<0.0001, Mann–Whitney U-test. British Journal of Anaesthesia  , DOI: ( /bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

6 Fig 5 The control of analgesia as a percentage of time of duration of anaesthesia. Data in mean (sd). The Analgoscore is a novel pain score developed from MAP and HR to monitor intraoperative nociception, which ranges from −9 to 9. ‘Excellent' represents an Analgoscore between −3 and 3; ‘Good' represents an Analgoscore ranging from −6 to −3 or from 3 to 6; ‘Insufficient' represents an Analgoscore ranging from −9 to −6 or 6 to 9; ‘Other' refers to periods where no score was determined. Data are presented as mean (sd). *P<0.05, Mann–Whitney U-test. British Journal of Anaesthesia  , DOI: ( /bja/aet001) Copyright © 2013 The Author(s) Terms and Conditions

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