Successful nonoperative management of chronic osteoarthritis pain of the knee: safety and efficacy of retreatment with intra-articular hyaluronans  Mark.

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Successful nonoperative management of chronic osteoarthritis pain of the knee: safety and efficacy of retreatment with intra-articular hyaluronans  Mark Pagnano, M.D., Geoffrey Westrich, M.D.  Osteoarthritis and Cartilage  Volume 13, Issue 9, Pages 751-761 (September 2005) DOI: 10.1016/j.joca.2005.04.012 Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 1 Visual analog scale (VAS) pain scores (0–100) after two courses of five weekly injections of sodium hyaluronate (MW 500–730kDa) in a retrospective survey of 52 patients with osteoarthritis of the knee38. All patients had followed a standard assessment protocol, and the mean interval between cycles 1 and 2 was 11.2 months. Osteoarthritis and Cartilage 2005 13, 751-761DOI: (10.1016/j.joca.2005.04.012) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions