Presentation is loading. Please wait.

Presentation is loading. Please wait.

Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,

Published byMaria Fernanda Ruth Marroquim Nunes Modified over 5 years ago

Similar presentations

Presentation on theme: "Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,"— Presentation transcript:

1 Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized, double-blind, dose- escalation, placebo-controlled study  H. Nagashima, M. Suzuki, S. Araki, T. Yamabe, C. Muto  Osteoarthritis and Cartilage  Volume 19, Issue 12, Pages (December 2011) DOI: /j.joca Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Study design. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Patient disposition.
Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 MMRM analysis of LS mean change from baseline in WOMAC pain (A), physical function (B), and stiffness (C) subscales, over time, FAS. SE: standard error. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

Download ppt "Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,"

Similar presentations

Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.

Efficacy of ultrasound therapy for the management of knee osteoarthritis: a systematic review with meta-analysis A. Loyola-Sánchez, J. Richardson, N.J.
The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy  P.T. Paradowski, L.S. Lohmander,
NASHA hyaluronic acid vs methylprednisolone for knee osteoarthritis: a prospective, multi-centre, randomized, non-inferiority trial  R. Leighton, C. Åkermark,

NASHA hyaluronic acid vs methylprednisolone for knee osteoarthritis: a prospective, multi-centre, randomized, non-inferiority trial  R. Leighton, C. Åkermark,
Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis  Z. Huang, J. Chen, J. Ma, B. Shen,

Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis  Z. Huang, J. Chen, J. Ma, B. Shen,
Short-term placebo response in trials of patients with symptomatic osteoarthritis: differences between hip and knee  S. Reiter-Niesert, M. Boers, J. Detert 

Short-term placebo response in trials of patients with symptomatic osteoarthritis: differences between hip and knee  S. Reiter-Niesert, M. Boers, J. Detert 
Efficacy and Safety of a Once-Daily Morphine Formulation in Chronic, Moderate-to- Severe Osteoarthritis Pain  Jacques R. Caldwell, MD, Ronald J. Rapoport,

Efficacy and Safety of a Once-Daily Morphine Formulation in Chronic, Moderate-to- Severe Osteoarthritis Pain  Jacques R. Caldwell, MD, Ronald J. Rapoport,
Dr L. S. Kim, N. D. , Dr L. J. Axelrod, N. D. , Dr P. Howard, M. D

Dr L. S. Kim, N. D. , Dr L. J. Axelrod, N. D. , Dr P. Howard, M. D
Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: a 13-week prospective, randomized, multicenter study 

Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: a 13-week prospective, randomized, multicenter study 
P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 

P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung 
Effectiveness of chondroitin sulphate in patients with concomitant knee osteoarthritis and psoriasis: a randomized, double-blind, placebo-controlled study 

Effectiveness of chondroitin sulphate in patients with concomitant knee osteoarthritis and psoriasis: a randomized, double-blind, placebo-controlled study 
Influence of flare design on symptomatic efficacy of non-steroidal anti-inflammatory drugs in osteoarthritis: a meta-analysis of randomized placebo-controlled.

Influence of flare design on symptomatic efficacy of non-steroidal anti-inflammatory drugs in osteoarthritis: a meta-analysis of randomized placebo-controlled.
Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials  M. Fransen, S.

Does land-based exercise reduce pain and disability associated with hip osteoarthritis? A meta-analysis of randomized controlled trials  M. Fransen, S.
Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants 

Association of knee pain with a reduction in thigh muscle strength – a cross-sectional analysis including 4553 osteoarthritis initiative participants 
A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled,

A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled,
Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role.

Avoidance of activity and limitations in activities in patients with osteoarthritis of the hip or knee: a 5 year follow-up study on the mediating role.
Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 

Osteoarthritis year 2011 in review: biochemical markers of osteoarthritis: an overview of research and initiatives  Y. Henrotin  Osteoarthritis and Cartilage 
Successful nonoperative management of chronic osteoarthritis pain of the knee: safety and efficacy of retreatment with intra-articular hyaluronans  Mark.

Successful nonoperative management of chronic osteoarthritis pain of the knee: safety and efficacy of retreatment with intra-articular hyaluronans  Mark.
A multicenter, randomized controlled trial comparing a single intra-articular injection of Gel-200, a new cross-linked formulation of hyaluronic acid,

A multicenter, randomized controlled trial comparing a single intra-articular injection of Gel-200, a new cross-linked formulation of hyaluronic acid,
Pre-operative interventions (non-surgical and non-pharmacological) for patients with hip or knee osteoarthritis awaiting joint replacement surgery – a.

Pre-operative interventions (non-surgical and non-pharmacological) for patients with hip or knee osteoarthritis awaiting joint replacement surgery – a.
Measuring and realizing the translational significance of preclinical in vivo studies of painful osteoarthritis  M. Hummel, G.T. Whiteside  Osteoarthritis.

Measuring and realizing the translational significance of preclinical in vivo studies of painful osteoarthritis  M. Hummel, G.T. Whiteside  Osteoarthritis.

Similar presentations

Ads by Google