Minimally Invasive Extracorporeal Bypass in Minimally Invasive Heart Valve Operations: A Prospective Randomized Trial Hardy Baumbach, MD, Christian J.

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Minimally Invasive Extracorporeal Bypass in Minimally Invasive Heart Valve Operations: A Prospective Randomized Trial Hardy Baumbach, MD, Christian J. Rustenbach, MD, Samir Ahad, MD, Ragi Nagib, MD, Marc Albert, MD, Dieter Ratge, MD, Ulrich F.W. Franke, MD, PhD The Annals of Thoracic Surgery Volume 102, Issue 1, Pages 93-100 (July 2016) DOI: 10.1016/j.athoracsur.2016.01.043 Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Levels of procalcitonin; p = 0.05 was determined using repeated-measure analysis of variance (RM ANOVA). (CECC = conventional extracorporeal circulation; CPB = cardiopulmonary bypass; MECC = minimally invasive extracorporeal circulation.) The Annals of Thoracic Surgery 2016 102, 93-100DOI: (10.1016/j.athoracsur.2016.01.043) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Levels of the proinflammatory interleukins IL-6 and IL-8; p = 0.575 and p = 0.677 were determined using repeated-measure analysis of variance (RM ANOVA). ). (CECC = conventional extracorporeal circulation; CPB = cardiopulmonary bypass; IL = interleukin; MECC = minimally invasive extracorporeal circulation.) The Annals of Thoracic Surgery 2016 102, 93-100DOI: (10.1016/j.athoracsur.2016.01.043) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Levels of the antiinflammatory interleukin (IL)-10; p = 0.601 was determined using repeated-measure analysis of variance (RM ANOVA). (CECC = conventional extracorporeal circulation; CPB = cardiopulmonary bypass; MECC = minimally invasive extracorporeal circulation.) The Annals of Thoracic Surgery 2016 102, 93-100DOI: (10.1016/j.athoracsur.2016.01.043) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Levels of tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ); p = 0.387 and p = 0.015 were determined using repeated-measure analysis of variance (RM ANOVA). (CECC = conventional extracorporeal circulation; CPB = cardiopulmonary bypass; MECC = minimally invasive extracorporeal circulation.) The Annals of Thoracic Surgery 2016 102, 93-100DOI: (10.1016/j.athoracsur.2016.01.043) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Levels of cell-free hemoglobin and haptoglobin; p = 0.684 and p = 0.522 were determined using repeated-measure analysis of variance (RM ANOVA). (CECC = conventional extracorporeal circulation; Hb-CF = cell-free hemoglobin; HLM = heart lung machine; MECC = minimally invasive extracorporeal circulation.) The Annals of Thoracic Surgery 2016 102, 93-100DOI: (10.1016/j.athoracsur.2016.01.043) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Levels of hemoglobin (Hb) and hematocrit (Hc); p = 0.026 and p = 0.021 were determined using repeated-measure analysis of variance (RM ANOVA). (CPB = cardiopulmonary bypass; CECC = conventional extracorporeal circulation; MECC = minimally invasive extracorporeal circulation.) The Annals of Thoracic Surgery 2016 102, 93-100DOI: (10.1016/j.athoracsur.2016.01.043) Copyright © 2016 The Society of Thoracic Surgeons Terms and Conditions