Genomewide Scan in German Families Reveals Evidence for a Novel Psoriasis- Susceptibility Locus on Chromosome 19p13  Young-Ae Lee, Franz Rüschendorf, Christine.

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Genomewide Scan in German Families Reveals Evidence for a Novel Psoriasis- Susceptibility Locus on Chromosome 19p13  Young-Ae Lee, Franz Rüschendorf, Christine Windemuth, Marcus Schmitt-Egenolf, Antje Stadelmann, Gudrun Nürnberg, Markward Ständer, Thomas F. Wienker, André Reis, Heiko Traupe  The American Journal of Human Genetics  Volume 67, Issue 4, Pages 1020-1024 (October 2000) DOI: 10.1086/303075 Copyright © 2000 The American Society of Human Genetics Terms and Conditions

Figure 1 Summary of the genome scan for psoriasis-susceptibility loci in 32 German extended families. The figure shows nonparametric multipoint GENEHUNTER PLUS Zlr (A) and LOD* score (B), across all autosomes, from pter to qter. Dotted lines indicate chromosome boundaries. The American Journal of Human Genetics 2000 67, 1020-1024DOI: (10.1086/303075) Copyright © 2000 The American Society of Human Genetics Terms and Conditions

Figure 2 Linkage analysis on chromosome 19, showing GENEHUNTER nonparametric LOD* score (Zall) and HLOD score, assuming a recessive model with high disease-allele frequency, as well as GENEHUNTER PLUS Zlr and nonparametric LOD score. Markers are arranged in map order, according to the final Généthon human linkage map (Dib et al. 1996). The American Journal of Human Genetics 2000 67, 1020-1024DOI: (10.1086/303075) Copyright © 2000 The American Society of Human Genetics Terms and Conditions

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