A Sweet New Role for EGFR in Cancer

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Presentation transcript:

A Sweet New Role for EGFR in Cancer Jeffrey A. Engelman, Lewis C. Cantley Cancer Cell Volume 13, Issue 5, Pages 375-376 (May 2008) DOI: 10.1016/j.ccr.2008.04.008 Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 1 EGFR Facilitates Glucose Transport This cartoon depicts two functions of EGFR. (Left) EGFR homodimerizes or heterodimerizes with other ERBB family members to promote downstream growth and survival signals. (Right) EGFR binds to SGLT1 and stabilizes its expression to promote glucose uptake. Cancer Cell 2008 13, 375-376DOI: (10.1016/j.ccr.2008.04.008) Copyright © 2008 Elsevier Inc. Terms and Conditions