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Three Down and One To Go: Modeling Medulloblastoma Subgroups

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1 Three Down and One To Go: Modeling Medulloblastoma Subgroups
Charles G. Eberhart  Cancer Cell  Volume 21, Issue 2, Pages (February 2012) DOI: /j.ccr Copyright © 2012 Elsevier Inc. Terms and Conditions

2 Figure 1 Medulloblastoma Subgroups
Transcriptional profiling supports the existence of four main medulloblastoma subgroups that differ with respect to their common microscopic appearance and clinical associations. The cartoons below depict a classic medulloblastoma comprised of heterogenous embryonal cells, a desmoplastic/nodular tumor with a central region of neuronal differentiation, and a large cell anaplastic medulloblastoma with increased nuclear size and pronounced cellular molding/engulfment. Cancer Cell  , DOI: ( /j.ccr ) Copyright © 2012 Elsevier Inc. Terms and Conditions

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