Antitussives Tulsi PH103.40

DEPARTMENT OF TECHNICAL EDUCATION ANDHRA PRADESH Name : R.D.L.P.Christian Designation : Lecturer in pharmacy Branch : Pharmacy Institute : GPW, Srikakulam(088) Year : I year Subject : Pharmacognosy Subject Code : PH-103 Topic : Antitussives Sub-Topic : Tulsi Duration : 50 min. Teaching Aids : PPT, Photographs PH103.40

In the last class we learnt about Recap In the last class we learnt about The plant drug TOLU BALSAM which can be used as an Antitussive agent Tolu balsam mainly contain resinous substances Having expectorant and Antitussive activity PH103.40

OBJECTIVES On completion of this lesson, you would be able to learn about The monograph of the Antitussive drug – TULSI PH103.40

Known to Unknown Which plant is called sacred plant? Do you find it is our Pharmacy garden? PH103.40

Antitussives - Definition Agents used in the symptomatic control of Cough Depress the cough centre present in the medulla Also termed as Anodyne, Cough suppressants and Centrally acting Antitussives PH103.40

TULSI Syn: Sacred basil, Holy basil, Tulasi (Telugu) Biological source : Leaves of Ocimum sanctum, Ocimum bassilicum Family : Labiatae Geographical Source : Annual herb found throught India (Holy Plant) Fig.40.1 Tulsi plant PH103.40

Morphological Characters LEAF Size : 2 -5cm long 1.5-3.2 cm wide Type : Simple Shape : Elliptic, oblong, obtuse or acute Colour : Green Odour : Aromatic Fig.40.2 Tulsi plant PH103.40

Morphological Characters LEAF Taste: Aromatic Apex: Acute Margin: Entire or serrate Base: Obtuse or acute Petiole: Slender Surface: Pubescent on both sides Fig.40.3 Tulsi plant PH103.40

Chemical Constituents Tulsi contains Volatile oil The oil contain about 70% Eugenol 20% methyl - Eugenol β - Caryophyllene Carvacrol Cineole Linalool Fig.40.4 Tulsi plant PH103.40

Collection and Preparation The leaves contain bright yellow coloured and pleasant Volatile oil The leaves and flowering tops are collected The oil is extracted by steam distillation PH103.40

Uses Tulsi has variety of activities It is having Hypoglycemic, Immunomodulatory, Antistress, Analgesic, Anti-pyretic, Anti-hypertensive, Anti-inflammatory, Anti-ulcer, Anti-tumour activities PH103.40

Uses The expectorant and CNS depressant properties are responsible for the Antitussive properties The oil shows Antibacterial activity against Mycobacterium tuberculosis Micrococcus pyogenes PH103.40

Summary In this class we learnt about The monograph of the Antitussive drug TULSI The active constituents is Volatile oil Tulsi is having a variety of activities apart from Antitussive activity PH103.40

Quiz a) Volatile oil The chief Active constituent of Tulsi b) Resins c) Latex d) None of the above PH103.40

Quiz The volatile oil of Tulsi is mainly present in a) Roots b) Stem c) Leaves d) None of the above PH103.40

Frequently Asked Questions Mention an anti-tussive drug with its source and chemical constituents Write the chemical constituents and uses of Tulsi Write the Botanical source, morphological characters and chemical constituents of Tulsi PH103.40

THANK YOU PH103.40