1.  : Guar gum and Gelatin Pharmaceutical Aids PH103.66 1

2. 2 Department of Technical Education Andhra Pradesh Name: BVSN Murty Designation : Lecturer in Pharmacy Branch: PHARMACY Institute: Govt. Polytechnic for Women, Srikakulam Year/Semester: I Year Subject: Pharmacognosy Subject code: PH103 Topic: Pharmaceutical Aids Duration: 50 Mts Sub Topic: Guar gum and Gelatin Teaching Aids: PPT, Photographs

3. Recap In the last class we learnt about : The monographs of Sodium Alginate Agar 3 PH103.66

4. 4 Objectives On completion of this period you would be able to know about : The monographs of Guar gum and Gelatin PH103.66

5. 5 Synonyms : Guar flour, Jaguar gum Biological source : Guar gum is the powder endosperm of seeds of Cyamopsis tetragonolobus. Family : Leguminosae Guar gum Fig.66.1 Guar gum plant

6. PH103.66 6 Guar gum Geographical Source : Gujarat Maharashtra Karnataka Rajasthan Pakistan

7. PH103.66 7 Guar gum Description : Colour : Colourless or pale yellowish- white coloured powder Odour : Characteristic Taste : Gummy and characteristic Solubility : Dispersible in water forming colloidal solution Insoluble in alcohol Fig.66.2 Guar gum

8. PH103.66 8 Identification tests: 1.Guar gum + Ruthenium red No Pink colour 2.Guar gum + 2% lead acetate Precpitate 3.Guar gum + weak solution of iodine No Olive green colour Guar gum

9. PH103.66 9 Chemical Constituents: Contents are divided into water-soluble and water insoluble parts Water soluble fraction consists about 85% of the gum is known as Guaran which is hydro-collooidal polysaccharide. Guaran on hydrolysis yields 35% of Galactose and 65% of Mannose. Guar gum also contains 5 to 7% proteins Guar gum

10. PH103.66 10 Uses : Thickening agent (It has 5 to 8 times more power than starch) Protective colloid Binding and Disintegrating agent Bulk laxative Guar gum

11. PH103.66 11 Uses : Appetite depressant In Peptic ulcer therapy Emulsifying agent In paper, Printing, Polishing and Textile industries In food and Cosmetic Industries Guar gum

12. PH103.66 12 Biological source: Gelatin is a product obtained by partial hydrolysis of collagenous materials. It is derived by boiling animal tissues like Skin Tendons Ligaments Bones Cartilage Gelatin

13. PH103.66 13 The above tissues are minced into small pieces and boiled with water Then it is skimmed and subjected to straining The resultant liquid is subsequently evaporated at a low temperature after purification and drying in air Now the product obtained is said to be Gelatin. Gelatin

14. PH103.66 14 Description : Colour : Colourless or pale yellow Odour: Characteristic Taste: Slight and broth-like Gelatin Fig.66.3 Gelatin

15. PH103.66 15 Chemical Constituents: Contains bout 17 to 20% of moisture 1.5 to 4 % of ash Gelatin chemically a protein known as Glutin On hydrolysis it yields non essential amino acids Gelatin

16. PH103.66 16 Identification tests: 1.Aqueous soln. of Gelatin + Solution of Trinitrophenol + Solution of Tannic acid 2. Gelatin solution + Soda lime Ammonia gas Gelatin Precipitate Heating

17. PH103.66 17 Uses : Valuable dietary supplement In the preparation of ice-creams (prevents formation of large ice crystals. In confectionery, preparation of candies, jellies, meat extracts As thickener in jams, jellies, salads etc., Gelatin

18. PH103.66 18 Uses : In manufacture of Capsules, pastilles, suppositories, urethral bogies, pastes and several cosmetic preps. Antidote for halogen poisoning. Substitute for blood plasma (in form of 6% Solution) In Bacteriology, preparation of nutrient media. As finishing agent in leather manufacturing Industry Gelatin

19. In this class we learnt about : Guar gum is a powder of endosperm of seeds of Cyamopsis tetragonolobus and used as thickening agent, Protective colloid, a binding and disintegrating agent Gelatin is obtained by partial hydrolysis of Collagenous materials derived by boiling animal tissues like skin, tendons, ligaments and bones with water. PH103.66 19 Summary

20. PH103.66 20 Quiz 1.Guar gum belongs to a.Leguminosae b.Apidae c.Solanaceae d.Graminae

21. PH103.66 21 Quiz 2.Gelatin is used in a.Bacteriology b.Manufacture of capsules c.Preparation of Ice-creams d.All of the above

22. PH103.66 22 Quiz 3.On heating Gelatin with soda lime liberates a.Nitrogen gas b.Carbon dioxide c.Ammonia gas d.None of the above

23. Frequently asked Questions 1.Write the Family, Chemical constituents and Uses of Guar gum 2.Write the monograph of Guar gum and Gelatin. 3.Write the Biological source, Chemical constituents and uses of Gelatin. 23 PH103.66