Coagulation factor X human Drugbank ID : Pharmacodynamics : The active substance in Coagadex is human factor X isolated from the plasma of blood donors. It replaces the missing factor X, thereby helping the blood to clot and giving temporary control of bleeding. Mechanism of action : Patients with hereditary factor X deficiency lack factor X, a protein needed to form the scab (blood clot) that stops wounds from bleeding. In these patients, blood clots do not form properly, resulting in longer bleeding time and poor wound healing. Blood may seep into surrounding tissues, resulting in local pain and swelling. Bleeding may also occur in internal organs. The active substance in Coagadex is human factor X isolated from the plasma of blood donors. It replaces the missing factor X, thereby helping the blood to clot and giving temporary control of bleeding.

Categories : Blood Coagulation Factors Brands : Coagadex Form : powder and solvent used to make a solution Route of administration : Intravenous Contraindication : Hypersensitivity to the active substance Side effects : The most common side effects with Coagadex (which may affect up to 1 in 10 people) are pain or redness at the injection site, fatigue (tiredness), and back pain.

Useful links http://www.coagadex.com/about-coagadex , http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/003855/human_med_001967.jsp&mid=WC0b01ac058001d124