CELL GROWTH & DIVISION 10-1 & 10-2 Image from: http://www.bcps.org/offices/lis/models/life/images/grow.JPG CELL GROWTH & DIVISION 10-1 & 10-2 The only time multiplication and Division mean the same thing! Image by Riedell

2 Reasons why cells divide DNA OVERLOAD 1. _____________________ As cell grows bigger demand on DNA “genetic library” becomes too great Ex: Small town library has 1000 books. As town grows and more people borrow books, there may be a waiting list to read the most popular titles http://www.adc.state.az.us/images/Off-Library.JPG

2 Reasons why cells divide Material exchange can’t keep up 2. _____________________ As cell grows bigger demand for transport across membrane is too great http://www.animationlibrary.com

Need for these depends on ___________ Ability to transport of oxygen, food, waste across cell membrane depends on _______________ Need for these depends on ___________ SURFACE AREA CELL VOLUME As cell grows these DON’T increase at the same rate

Ratio of Surface Area to Volume in Cells Section 10-1 Cell Size Surface Area (length x width x 6) Volume (length x width x height) Ratio of Surface Area to Volume

BIGGER CELLS NEED MORE FOOD and OXYGEN, but CAN’T TRANSPORT IT FAST ENOUGH or IN BIG ENOUGH QUANTITIES! http://www.animationlibrary.com

mainly by increasing cell number Image from: http://www.bcps.org/offices/lis/models/life/images/grow.JPG Image by Riedell Multicellular organisms grow mainly by increasing cell number

DNA in PROKARYOTES BACTERIAL DNA is CIRCULAR HAVE ONE CHROMOSOME NO NUCLEUS; ATTACHED TO CELL MEMBRANE http://www.origin-life.gr.jp/3202/3202121/fig6.jpg

CELL DIVISION in PROKARYOTES Bacteria reproduce by simply getting larger, copying their DNA, and then splitting in two. http://fig.cox.miami.edu/~cmallery/150/mitosis/fission.jpg

DNA in EUKARYOTES (Plants & Animals) DNA is ROD-SHAPED CHROMOSOMES MANY PAIRS FOUND IN NUCLEUS http://cellbio.utmb.edu/cellbio/chrom2.jpg

DNA CAN BE: SPREAD OUT IN NON-DIVIDING CELLS SCRUNCHED UP IN DIVIDING CELLS CHROMATIN CHROMOSOMES

Chromosome structure CHROMATIDS CENTROMERE ___________________ 2 identical arms __________________ constricted area holds chromatids together CENTROMERE

CELL CYCLE ______________ : the series of events that cells go through as they grow and develop

CELL CYCLE INTERPHASE – non-dividing phase G1- Grow bigger Cell is “doing its job” DNA is spread out as chromatin S - Synthesis (copy DNA) & chromosomal proteins G2- Grow bigger, make organelles & molecules needed for cell division M – Mitosis AND cytokinesis

CELL DIVISION MITOSIS – Nuclear division (4 STAGES) Prophase Metaphase Anaphase Telophase Cytokinesis – Cytoplasm divides G0 – cell stops dividing (Ex: nerve cell)

Figure 10–4 The Cell Cycle Section 10-2 G1 phase M phase S phase

INTERPHASE (G1 - S - G2) Can’t see chromosomes Between divisions Cells are in this phase most of the time Can see nucleus DNA spread out as chromatin Can’t see chromosomes DNA gets copied (S) Cell gets ready to divide

PROPHASE 1st dividing phase DNA scrunches into chromosomes Pearson Education Inc publishing as Pearson Prentice Hall PROPHASE 1st dividing phase http://www.life.uiuc.edu/plantbio/102/lectures/08mit&veg102.html DNA scrunches into chromosomes Centrioles appear in centrosome region & move to poles Nuclear membrane & nucleolus disappear Spindle fibers form & attach to chromosomes

METAPHASE middle Chromosomes line up in _____ Spindle fibers attach to centromeres

ANAPHASE Centromeres split Centrioles pull chromatids_______ apart

two TELOPHASE (reverse prophase steps) See ______ nuclei Nuclear membrane & nucleolus return Chromosomes spread out as chromatin Centrioles disappear Spindle fibers disappear Images from: Pearson Eduction Ince; Publishing as Pearson Prentice Hall http://www2.bc.cc.ca.us/cnewton/Biology%2011/Mitosis.html

CYTOKINESIS Cytoplasm splits into 2 cells CLEAVAGE FURROW ANIMAL CELLS pinch cytoplasm in two with a ______________________ CLEAVAGE FURROW

CYTOKINESIS Cytoplasm splits into 2 cells PLANT CELLS can’t pinch because they have a sturdy ____________ Plant cells separate cytoplasm by growing a _______________ down the middle. CELL WALL CELL PLATE http://www.eastcentral.edu/acad/depts/BI/plant_mitosis_nolabels.html

Figure 10–5 Mitosis and Cytokinesis Section 10-2 Spindle forming Centrioles Chromatin Centromere Nuclear envelope Centriole Chromosomes (paired chromatids) Interphase Prophase Spindle Cytokinesis Centriole Metaphase Telophase Individual chromosomes Anaphase Nuclear envelope reforming

Figure 10–5 Mitosis and Cytokinesis Section 10-2 Spindle forming Centrioles Chromatin Centromere Nuclear envelope Centriole Chromosomes (paired chromatids) Interphase Prophase Spindle Cytokinesis Centriole Metaphase Telophase Individual chromosomes Anaphase Nuclear envelope reforming

Figure 10–5 Mitosis and Cytokinesis Section 10-2 Spindle forming Centrioles Chromatin Centromere Nuclear envelope Centriole Chromosomes (paired chromatids) Interphase Prophase Spindle Cytokinesis Centriole Metaphase Telophase Individual chromosomes Anaphase Nuclear envelope reforming

Figure 10–5 Mitosis and Cytokinesis Section 10-2 Spindle forming Centrioles Chromatin Centromere Nuclear envelope Centriole Chromosomes (paired chromatids) Interphase Prophase Spindle Cytokinesis Centriole Metaphase Telophase Individual chromosomes Anaphase Nuclear envelope reforming

Figure 10–5 Mitosis and Cytokinesis Section 10-2 Spindle forming Centrioles Chromatin Centromere Nuclear envelope Centriole Chromosomes (paired chromatids) Interphase Prophase Spindle Cytokinesis Centriole Metaphase Telophase Individual chromosomes Anaphase Nuclear envelope reforming

Figure 10–5 Mitosis and Cytokinesis Section 10-2 Spindle forming Centrioles Chromatin Centromere Nuclear envelope Centriole Chromosomes (paired chromatids) Interphase Prophase Spindle Cytokinesis Centriole Metaphase Telophase Individual chromosomes Anaphase Nuclear envelope reforming

Concept Map Cell Cycle Section 10-2 includes is divided into

Concept Map Cell Cycle Section 10-2 includes M phase (Mitosis) Interphase is divided into is divided into G1 phase S phase Prophase G2 phase Metaphase Telophase Anaphase