The Latest Data on Oral Prostacyclin Therapy in PAH

Program Overview

Background

Case Study 1

Risk Assessment in PAH

Case Study 1 Diagnosis and Treatment Plan

Case Study 1: Ten Months Later

Guideline-Recommended Treatment Options for Patient on PDE5I Monotherapy

Case Study 1 on Dual Combination Therapy

Case Study 1: Three Years Post Diagnosis

Recommendations for Treatment Escalation in Patient on Background ERA + PDE5I

Case Study 1 Therapy Escalation

GRIPHON: Treatment Effect by Subgroup

Initial Treatment Decision

Low-Risk Criteria at Diagnosis and at First Reevaluation

Case Study 2

Diagnostic and Therapeutic Dilemmas in Complex Patients With Scleroderma

The Rationale for Combination Therapy

Recommendations for Initial Combination Therapy

French Registry: Survival Based on Number of Low-Risk Criteria Achieved at First Evaluation

Case Study 2: Two-Month Follow Up

Therapy Escalation: Treatment Decision

GRIPHON Study Design

Effect of Selexipag on Primary Composite Endpoint in GRIPHON

Concluding Remarks

Abbreviations

Abbreviations (cont)

Abbreviations (cont)