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All About PAH:.

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Presentation on theme: "All About PAH:."— Presentation transcript:

1 All About PAH:

2

3 Case Study Initial Presentation

4 Case Study Past Medical History

5 Case Study Physical Exam

6 Case Study Test Results

7 Case Study RHC Results

8 Algorithm for Treatment-Naive PAH Patient

9 Risk Assessment in PAH

10 Monotherapy Therapy Recommendations for WHO FC III PAH

11 Sequential Combination Therapy Recommendations for WHO FC III PAH

12 Recommendations for Initial Combination Therapy for WHO FC III

13 AMBITION Study

14 An Evolving Paradigm From Sequential to Initial Upfront Combination Therapy

15 Case Study Patient Initiates PAH Treatment

16 Case Study Follow-Up 4 Months Later

17 Case Study Follow-Up Echo

18 Algorithm for Patient Receiving PAH Treatment

19 French Registry

20 French Registry (cont)

21 French Registry Predictive Value of Individual Variables

22 French Registry: Survival Based on Number of Low-Risk Criteria Achieved at First Evaluation

23 COMPERA Registry Risk Stratification

24 Swedish Registry: Comprehensive Risk Stratification at Early Follow-up Determines Prognosis

25 Case Study Patient Not at Goal

26 GRIPHON Study Design

27 Effect of Selexipag on Primary Composite Endpoint in GRIPHON

28 GRIPHON Treatment Effect by Subgroup

29 GRIPHON: Selexipag Titration and Dosing

30 Case Study Follow-Up and RHC Results

31 Pilot Study Initial Triple Combination Therapy

32 Initial Triple Therapy

33 Concluding Remarks

34 Abbreviations

35 Abbreviations (cont)

36 Abbreviations (cont)

37 Abbreviations (cont)


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