INNATE HOST DEFENSES CHAPTER 16.

Slides:



Advertisements
Similar presentations
Innate Immunity (part 1) BIOS 486A/586A
Advertisements

Chapter 16: Nonspecific Immunity
Natural Defense Mechanisms. Immunology Unit. College of Medicine & KKUH.
Chapter 14: Innate Immune System. Overview of Immune Defenses First-line defenses: – Intact, healthy skin and mucous membranes – Normal microbiota.
NONSPECIFIC HOST DEFENSES Innate (nonspecific immunity) Defenses present at birth.
Anatomy and Physiology For The First Class 2 nd Semester 1.
The Immune Stystem.
اجزاء سيستم ايمني Components of Immune System بافتها و اعضاء سيستم لنفاوي Lymphoid Organs سلولهاي لنفاوي Lymphoid Cells.
First line of defense (non-specific barriers) : physical and chemical barriers that prevent pathogens from entering (skin, mucus, acids in the stomach,
An Overview of the Body’s Defenses. The first line of defense, the skin and mucous membranes, prevents most microbes from entering the body.
Chapter 24 The Immune System
Immunology: Innate Immunity
Lymphatic System The Body’s Defense System. Nonspecific Defense First Line of Defense –Skin –Mucous Membrane –Secretions.
Lymphatic and Immune System The Body’s Defense. Nonspecific Defense First Line of Defense –Skin –Mucous Membrane –Secretions.
Basic Immunology Mr.AYMAN.S.YOUSIF
The Immune System.
Immune System Overview. GOT DEFENSE? ANATOMY OF THE IMMUNE SYSTEM The immune system is localized in several parts of the body –immune cells develop.
CHAPTER10 Biomaterial Implantation and Acute Inflammation 10.1 Introduction: Overview of Innate and Acquired Immunity Wound healing Implantation --- assault.
Human Anatomy and Physiology
Immunity Biology 2122 Chapter 21. Introduction Innate or nonspecific defense: – First-line of defense – Second-line of defense The adaptive or specific.
Innate Immunity Present before exposure to pathogens Present at birth Non-antigen specific Consists of: – Skin… barrier for microbes and viruses Compromised.
The Immune System Dr. Jena Hamra.
Nonspecific Defense Against Disease Section 33.2.
1 Host Defenses Adaptive Innate. 2 Defense Barriers Physical Chemical Cellular defenses Inflammation Fever Molecular defenses.
Overview on Immunology and Introduction to Innate Immunity
The Immune System Chapter 43 ~. PCA: List the organs involved in the immune sytem:
Lymphatic Organs Primary lymph organs are the bone marrow and thymus. – Sites where stem cells divide and become immunocompetent (capable of mounting an.
Human Immunity Non-specific Immunity. Non-Specific Immunity  Non-specific = doesn’t distinguish between types of infectious agents  Innate  1 st line.
Chapter Pgs This is challenging material!!! *Don’t think black & white: There are always exceptions… Objective: I can describe the basic.
Activity…  Design an emergency plan to protect people (ex. LRHS students or people attending a concert) from an attack.  If an attack were to occur,
GENERAL IMMUNOLOGY PHT 324
The Lymphatic System and Body Defenses
Dr. Sinan Bahjat Issa M B Ch B, M Sc, F I B M S
Chapter 15.
The Basics of Immunology
IMMUNE SYSTEM NON-SPECIFIC DEFENSE

Innate Immune Response (Ch14)
Blood Cells.
Immunology The study of the physiological mechanisms that humans and animals use to defend their bodies from invasion by microorganisms. The immune system.
INNATE HOST DEFENSES CHAPTER 16
Chapter 18 Warm-Up Define the following terms:
The immune system Chapter 43.
Objective Immunity There are two intrinsic defense systems involved in protecting human organisms from disease: Non-Specific (innate) systems Specific.
Burton's Microbiology for the Health Sciences Chapter 15
BODY DEFENSE SYSTEM.
Chapter 43 Warm-Up Define the following terms:
Chapter 43 Warm-Up Define the following terms:
Chapter 16 Nonspecific defenses of the host
Nonspecific (Innate) Host Resistance
Chapter 15 Innate Immunity
Chapter 43 The Immune System.
Chapter 24 The Immune System.
Chapter 43 Warm-Up Define the following terms:
The immune system Chapter 43.
Lines in Defense in the Body
Chapter 36-2: Defense Against Infectious Disease
Chapter 16– Nonspecific Defense
Immune System.
The Lymphatic System and Body Defenses
16 Innate Immunity: Nonspecific Defenses of the Host.
The Immune System Chapter 43 ~.
One of the great joys in life is to be almost run off the road by a maniac driver and then see a Jesus fish on their bumper.
Chapter 43 Warm-Up Define the following terms:
Chapter 35 Innate Immunity.
Immune system and its importance for homeostasis.
Our ability to recognize and respond to pathogens or foreign cells
Unit 4.1 Day 2.
Animal Defense Mechanisms… Immunity
Presentation transcript:

INNATE HOST DEFENSES CHAPTER 16

Host Defenses Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. Adaptive immune systems composed of highly specialized, systemic cells and processes that eliminate or prevent pathogenic challenges. Thought to have arisen in the first jawed vertebrates, the adaptive or "specific" immune system is activated by the innate immune system.

Defense Barriers Physical skin/mucous membrane Chemical antimirobial substances in body fluids. Ex. Lysozyme Cellular defenses phagocytes Inflammation swelling, reddening, histamine response Fever pyrogenic Molecular defenses interferon, complement

Physical Barriers Skin- keratinized Mucous membranes

Chemical Barriers Salt pH Lysozyme Transferin Lactoferrin Defensins

Cellular Defenses - Granulocytes Basophils/Mast cells Eosinophils Neutrophils Dendritic cells most abundant migrate toward the site of inflammation predominant cells in pus store histamine, inflammatory response 1-6% of white blood cells ROS and ILs process antigen material and present it on the surface to other cells of the immune system

Cellular Defenses — Agranulocytes Monocytes Lymphocytes natural killer cells (NK cells) small lymphocytes are the T cells and B cells (1) replenish resident macrophages and dendritic cells under normal states, and (2) in response to inflammation signals, monocytes can move quickly (approx. 8-12 hours) to sites of infection in the tissues and divide/differentiate into macrophages and dendritic cells to elicit an immune response

Blood Cells

Phagocytosis Cells Involved = macrophages Process Chemotaxis Adherence Ingestion Digestion

Nucleus Cytoplasmic membrane of phagocyte Phagolysosome Myeloperoxidase NADPH oxidase Nitric oxide synthase Phagolysosome Phagocytosed bacteria

Characteristics of Inflammation Acute Inflammation Repair/ Regeneration Chronic Inflammation

Fever Exogenous/Endogenous Pyrogens Benefits/Risks Leukocyte Endogenous Mediator

Interferon Interferon protein

Complement System

Complement System

Complement — Cytolysis

Complement — Cytolysis

Non-specific Defenses

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2024 SlidePlayer.com Inc. All rights reserved.