facioscapulohumeral muscular dystrophy Chapter 4: Chromosome: 4 DNA Sequence Chromosome 21,840 bp Name of Protein 4 Name of Gene Toll-like receptor2 TLR2 transcription Amino acid sequence mRNA 784aa Cytoplasm translation What does this protein make up or do? It passes on appropriate signals to the cells of the immune system. A Cell Nucleus Condition/Disease facioscapulohumeral muscular dystrophy

Description of muscular dystrophy Symptoms and characteristics Facioscapulohumeral muscular dystrophy disease is a type of weakness and wasting of muscles generally around the face and shoulder blade and upper arms. First symptoms are usually weakness around the mouth and(hard to whistle, drink from a straw..etc...) eyes, than weakness moves to shoulder blades and so on making it hard to rise from chairs. If muscular dystrophy remains untreated, the outcome of what will happen will not change. Muscular dystrophy is detected through a physical exam, a family medical history, and tests.

Description of muscular dystrophy (cont.) Who is affected? Anyone, but the following have a higher risk: People with a family history of it. Or a parent whose had it. Outlook or quality of life medications and therapy can slow down the process of the disease There is no cure for muscular dystrophy ; but patients can build up the remaining muscles. Researcher: MW

References www.webmd.com/.../understanding-muscular-dystrophy-treatment http://www.news-medical.net/health/What-is-Chromosome-4.aspx. http://ghr.nlm.nih.gov/chromosome/4/show/Genes http://www.ncbi.nlm.nih.gov/projects/genome/guide/human/index.shtml