Catabolism of sugars other than glucose

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Metabolism of Monosaccharides and Disaccharides

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Presentation transcript:

Catabolism of sugars other than glucose

Dietary sugars other than glucose Trivial name Composition Source lactose (milk sugar) disaccharide of glucose and galactose milk sucrose disaccharide of glucose and fructose sugar cane, sugar beet, other fruits fructose monosaccharide various fruits sorbitol sugar alcohol fruits; semisynthetic ribose, deoxyribose monosaccharides nucleic acids

Degradation of fructose and sucrose

The fructolysis pathway

Fructose intolerance

Lactose and galactose

The Leloir pathway for galactose utilization

Mechanism of UDP-galactose epimerase

Lactose intolerance

Galactosemia Type Enzyme deficiency Accumulating metabolites I galactose-1-phosphate-uridyltransferase galactose, galactose-1-phosphate, galactitol, galactonate II galactokinase galactose, galactitol III UDP-galactose epimerase galactose-1 phosphate, UDP-galactose

Sorbitol is an intermediate of the polyol pathway