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Copyright © 2013 American Medical Association. All rights reserved. From: Breast CancerA Review for the General Surgeon JAMA Surg. 2013;148(10):971-980. doi:10.1001/jamasurg.2013.3393 Figure Legend: Simplified Algorithm for Surgical Management of Biopsy-Proved Breast DiseaseADH indicates atypical ductal hyperplasia; ALH, atypical lobular hyperplasia; DCIS, ductal carcinoma in situ; SLNB, sentinel lymph node biopsy; and XRT, radiation therapy. Date of download: 10/14/2017 Copyright © 2013 American Medical Association. All rights reserved.

Copyright © 2013 American Medical Association. All rights reserved. From: Breast CancerA Review for the General Surgeon JAMA Surg. 2013;148(10):971-980. doi:10.1001/jamasurg.2013.3393 Figure Legend: Twenty-Year Follow-up of NSABP B-06 Survival CurvesDisease-free survival (A), distant disease–free survival (B), and overall survival (C) among 589 women treated with total mastectomy, 634 treated with lumpectomy alone, and 628 treated with lumpectomy plus irradiation. P values above the lines are for 3-way comparison among the groups. P values below the lines are for 2-way comparisons between lumpectomy alone or with irradiation and total mastectomy. NSABP B-06 indicates National Surgical Adjuvant Breast and Bowel Project B-06. Reproduced with permission from Fisher et al. Date of download: 10/14/2017 Copyright © 2013 American Medical Association. All rights reserved.

Copyright © 2013 American Medical Association. All rights reserved. From: Breast CancerA Review for the General Surgeon JAMA Surg. 2013;148(10):971-980. doi:10.1001/jamasurg.2013.3393 Figure Legend: Twenty-Year Follow-up of NSABP B-06 Ipsilateral Breast Recurrence in Lumpectomy and Lumpectomy Plus Irradiation GroupsCumulative incidence of a first recurrence of cancer in the ipsilateral breast during 20 years of follow-up among 570 women treated with lumpectomy alone and 567 treated with lumpectomy plus breast irradiation. The data are for women whose specimens had tumor-free margins. NSABP B-06 indicates National Surgical Adjuvant Breast and Bowel Project B-06. Reproduced with permission from Fisher et al. Date of download: 10/14/2017 Copyright © 2013 American Medical Association. All rights reserved.