Ari Brooks, MD Cancer Surgeon, Big Data End User

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Presentation transcript:

Ari Brooks, MD Cancer Surgeon, Big Data End User 39 year old woman with a 2cm left breast cancer Family History: mother and maternal aunt breast CA GYN History: menarche age 12 G3P2 age 1st birth 32 Imaging: Mammogram, Ultrasound, MRI Pathology: Invasive Ductal Cancer ER+ PR+ Her2- Surgical Options: Lumpectomy, Mastectomy (or two) Radiation: Yes, type of delivery and dose Chemotherapy: Oncotype (precision medicine?) Hormone therapy: Yes, type? Surveillance: blood? Imaging? Exams

Complexity Map Age Gender Race Site Geography Time Family History Pedigree Somatic Genome GYN History Medical History Medication History Imaging: Mammo 9GB MRI 2GB Tumor size morphology invasion nodes Tumor Genome Gene expression Treatment: Surgery Radiation Chemotherapy Molecular therapy Hormone Follow up type time local recurrence metastasis time death of disease time