Glycated hemoglobin and long-term prognosis in patients with suspected stable angina pectoris without diabetes mellitus: A prospective cohort study Eirik.

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Glycated hemoglobin and long-term prognosis in patients with suspected stable angina pectoris without diabetes mellitus: A prospective cohort study Eirik Wilberg Rebnord, Eva Ringdal Pedersen, Elin Strand, Gard Frodahl Tveitevåg Svingen, Klaus Meyer, Hall Schartum-Hansen, Kjetil Halvorsen Løland, Reinhard Seifert, Per Magne Ueland, Dennis W.T. Nilsen, Jan Erik Nordrehaug, Ottar Nygård Atherosclerosis Volume 240, Issue 1, Pages 115-120 (May 2015) DOI: 10.1016/j.atherosclerosis.2015.02.053 Copyright © 2015 The Authors Terms and Conditions

Fig. 1 Plasma HbA1c levels and risk of major coronary events in 2519 non-diabetic patients with suspected coronary artery disease. The association between glycated hemoglobin (HbA1c) levels (%) and risk of major coronary events obtained by generalized additive regression. The simple model (left panel) is adjusted for age and gender. The multivariate model (right panel) is additionally adjusted for current smoking, hypertension, number of significantly stenosed coronary arteries (0–3), left ventricular ejection fraction, revascularization following angiography (none, percutaneous coronary intervention or coronary artery bypass graft surgery), previous acute myocardial infarction, estimated glomerular filtration rate, C-reactive protein, body mass index, apolipoprotein A-I, apolipoprotein B, and treatment with statins and aspirin. The solid lines denote hazard ratios and the shaded areas the 95% confidence interval. Density plots show the distribution of HbA1c, and vertical lines denote values of 5.0% and 5.7%. Atherosclerosis 2015 240, 115-120DOI: (10.1016/j.atherosclerosis.2015.02.053) Copyright © 2015 The Authors Terms and Conditions