Somatosensory System and Pain Prof. Marshall Devor, Ph.D. Dept. of Cell & Animal Biology and Center for research on Pain Institute of Life Sciences Hebrew.

Slides:

Advertisements

Similar presentations

Ascending tracts and general sensory neuro stuff 

Advertisements

Ascending & Descending nerve tracts

Essam Eldin AbdelHady Salama

Somatic Sensation of the Face and Head

No. 26 Sensory Pathways (1).

Long Sensory Pathways (Somatic Sensation) David A. Morton, Ph.D. Thursday January 31 st, Anterolateral System (Pain and Temperature Pathway) - DCML.

Ascending Sensory Pathways

The cranial nerves. Central Nervous System - Brain Identify the anatomical location of each major brain area. Describe the functions of the major brain.

Anatomical Substrates of Somatic Sensation

LIMBIC SYSTEM NBIO 401 Friday, December 3, 2010 Robinson.

Somatic Sensory Pathways

Nervous System Physiology

Click to Play! Neuro Quiz  Michael McKeough 2008 Identify the correct question The Somatic Sensory System.

Somatosensory System and Pain

The Fore Brain Diencephalon.

Anatomy of the Spinal Cord  Structure of the spinal cord  Tracts of the spinal cord  Spinal cord syndromes Anatomy of the Spinal Cord  Structure of.

פיסיולוגיה מורחב 08-9 Somatosensory System and Pain

Sign in: password: ihuilee.

Part 6 The Sensory Function of CNS. Sensation production Changes of internal and external environment Interoceptor and exteroceptor Sensation conduction.

Somatosensory System and Pain Prof. Marshall Devor, Ph.D. Dept. of Cell & Animal Biology and Center for research on Pain Institute of Life Sciences Hebrew.

Spinal Cord Organization January 9, Spinal Cord 31 segments terminates at L1-L2 special components - conus medularis - cauda equina no input from.

Bear: Neuroscience: Exploring the Brain 3e

PAIN !!! DENT/OBHS 131 Neuroscience Pain…. Is a submodality of somatosensation Is the perception of unpleasant or aversive stimulation (sensory.

Practical Neuroanatomy Lecture 4 Christine Hulette MD General Sensation and Review.

Chapter 19 Viscerosensory Pathways MP. Thibeault-Eybalin, R4 Academic Half-Day March 25 th, 2009.

Somatosensory System and Pain Prof. Marshall Devor, Ph.D. Dept. of Cell & Animal Biology and Center for Research on Pain Institute of Life Sciences Hebrew.

First Term Functions Second Term Functions First Term.

The Autonomic Nervous System Assess Prof. Fawzia Al-Rouq Department of Physiology College of Medicine King Saud University Pathways of proprioception posterior.

Somatic Sensory System Sensation arising from skin muscle joints Allow you to survive in your environment and make appropriate motor responses.

Pain pathway Y Tang.

Central Nervous System. Lecture Outline Spinal Cord Design & Function Functional Brain Regions –Flow of Information –Learning.

Central nervous system (CNS) Brain + Spinal Cord

Somatic Senses General Sensory System. Sensation Define Stimulus Type Sensory Organ Sensory Receptors Exteroceptors Interoceptors Proprioceptors Receptor.

Cogs 107b – Systems Neuroscience lec03_ – tactile sensation (a.k.a., touch sense or mechanoreception) the weekly principle: ‘topographic.

The Anterolateral System Pain and Temperature Transmision.

Neural Integration I: Sensory Pathways and the Somatic Nervous System

SENSORY (ASCENDING) SPINAL TRACTS

Ascending Tracts of the Spinal cord. Objectives Define the meaning of a tract. Distinguish between the different types of tracts. Locate the position.

Medical Neuroscience Dr. Wiegand

Dr Abdulrahman Alhowikan Collage of medicine Physiology Dep. Pathways of Proprioception.

Proprioception and Discriminative Touch – Dorsal Column/Medial Lemniscus System.

مسیرهای انتقال حسهای پیکری

Somatosensory System 2217 – 2006 Week 7 Dr Avinash Bharadwaj.

ORGANIZATION OF THE NERVOUS SYSTEM D. C. Mikulecky Professor of Physiology.

IV. Thalamic Afferent/Efferent Connections A.Sensory Thalamus – Somatosensory & gustatory VPM Afferent – Trigeminothalamic fibers (pain, temperature, touch.

Somatosensory Pathways Lectures Organization of the Course Spinal Cord Brainstem/ Cerebellum Sensory Pathways Cerebrum Motor Pathways Cranial Nerves.

Sensory and Motor Systems Psychology Introduction The nervous system basically goes sensory -> inter -> motor neurons The nervous system basically.

Chapter 22 Fundamentals of Sensory Systems

The nervous pathway SHANDONG UNIVERSITY Liu Zhiyu

05. The Trigeminal System Somatic Sensation of the Face and Head David A. Morton, Ph.D. Thursday February 7 th, 2013.

Dr.Roshith Chekkadan Dr.Rohith Chekkadan. Pain is standard, evolutionary drawn pathologic process, which appears during the effect of damaging(nociceptive.

SC.912.L  What are the major parts of the spinal cord?

Introduction to Neuroanatomy II: Functional Anatomy.

DISCRIMINATIVE TOUCH, VIBRATORY SENSE, AND CONSCIOUS MUSCLE JOINT SENSE (Dorsal column-medial leminiscus tract/system) Lufukuja G.

Somatosensory System and Pain Prof. Marshall Devor, Ph.D. Dept. of Cell & Animal Biology and Center for Research on Pain Institute of Life Sciences Hebrew.

Ascending Sensory System

Sensory system.

PSY2301: Biological Foundations of Behavior Somatosensory System Chapter 11.

Somatosensory Tracts and Maps NBIO 401 – Wednesday October 2, 2013.

ASCENDING PATHWAYS. Ascending Pathways Three-neuron pathways: Three-neuron pathways: Primary sensory neurons: From external receptors Travel through dorsal.

Int. Environ. Ext. environ. Sensory N.S.. Sensation. Reaction. Body func. Cont. Sensory N.S.. Sensory receptor. Afferent Nerve. CNS(sensory center)

SENSORY OR ASCENDING TRACTS

Anatomy of the Spinal Cord The ascending and descending tracts Anatomy of the Spinal Cord The ascending and descending tracts.

Ascending Tracts. Internal Structure of the Spinal Cord Grey matter –cervical and lumbar enlargements White matter –most abundant superiorly.

Somatosensory Pathways

Pain systems Domina Petric, MD.

פיסיולוגיה מורחב Somatosensory System and Pain

10 October ) Turn in Take-Home Quiz on van Gammeren et al. paper. 2) Take in-class quiz on Cranial Nerves and Somatic & Autonomic Motor Systems Lecture:

Emeran A. Mayer, Bruce D. Naliboff, A.D. Bud Craig Gastroenterology

Spinal cord Domina Petric, MD.

Presentation transcript:

Somatosensory System and Pain Prof. Marshall Devor, Ph.D. Dept. of Cell & Animal Biology and Center for research on Pain Institute of Life Sciences Hebrew University of Jerusalem lecture 6: Ascending pathways 08-9 פיסיולוגיה מורחב

primary sensory neurons perception vs. regulation

Spinal white matter pathways anterolateral column dorsal column

dorsal column – medial lemniscus system hand foot A  LTM afferents

dorsal column nuclei thalamus (ventro-basal nucleus) VPL, VPM somatosensory cortex (S1) dorsal column – medial lemniscus system light touch and vibration sense

anterolateral column system (spino-bulbo-thalamic system) all types of afferents hand foot

thalamus (ventro-basal nucleus) VPL, VPM somatosensory cortex (S1) spino-bulbo- thalamic system which sense ? brainstem nuclei "bulbo-"

spino-bulbo- thalamic system

dorsal column – medial lemniscus system light touch and vibration spino-bulbo-thalamic system which sense ?? tabes dorsalis

anterolateral column system (spino-bulbo-thalamic system) all types of afferents hand foot

dorsal column – medial lemniscus system light touch and vibration spino-bulbo-thalamic system all somato-visceral senses

primary sensory neurons “medial pain pathway” lamina I (nociceptive)  parabrachial n. (pons)  amygdala + hypothalamus

succinyl dehydrogenase barrel field (van der Loos)

homunculus

functional magnetic resonance imaging fMRI

saggital human brain anterior cingulate gyrus

CCoghill et al constant stimulus, variable sensory response among subjects

propriospinal system propriospinal tract

Somatosensory System and Pain Prof. Marshall Devor, Ph.D. Dept. of Cell & Animal Biology and Center for research on Pain Institute of Life Sciences Hebrew University of Jerusalem lecture 6: Ascending pathways פיסיולוגיה מורחב

primary sensory neurons

heterogeneity of primary afferents (  labeled line theory) heterogeneity of primary afferents (  labeled line theory) divergence + convergence  different heterogeneity of second divergence + convergence  different heterogeneity of second order projection neurons order projection neurons (2x specific, WDR, multireceptive) (2x specific, WDR, multireceptive) dynamic (RF size & response properties, central sensitization ) dynamic (RF size & response properties, central sensitization ) multiple ascending pathways multiple ascending pathways multiple terminal areas multiple terminal areas descending control (feedback, feedforward, anticipation) descending control (feedback, feedforward, anticipation) A Q P A Q P for every unique stimulus, a unique constellation of neural population activity Population activity theory "Population activity theory" “bottom-up” vs. “top-down”