1. What are free radicals? Why are they damaging to the human body? - by Newman Doo

2. Our body tissues are made up of cells.

3. Each cell is composed of many different types of molecules. Molecules consist of one or more atoms of one or more elements joined by chemical bonds.

4. An atom The number of protons (positively charged particles) in the atom nucleus determines the number of electrons (negatively charged particles) surrounding the atom.

5. Electrons Electrons surround, or "orbit" an atom in one or more shells.

6. How is Free Radical Formed? When a electron is lost from an atom, an unstable free radical is formed.

7. Chain reaction of radical formation. When the molecule loses its electron, it becomes a free radical, beginning a chain reaction. Once the process is started, it can cascade.

8. How a cell is damaged. Finally a living cell is disrupted.

9. Causes of free radical formation- oxidative stress Environmental factors such as pollution, radiation, cigarette smoke and herbicides also spawn free radicals.

10. Many drugs cause free radicals Drugs adriamycin bleomycin mitomycin C nitrofurantoin chlorpromazine

11. Stress The pressures common in industrial societies can trigger the body's stress response. In turn, the stress response creates free radicals in abundance.

12. Viruses and bacteria Sometimes the body immune system cells purposefully create free radicals to neutralize viruses and bacteria.

13. Sports Oxygen, although essential to life, is the source of the potentially damaging free radicals. Endurance exercise can increase oxygen utilization from 10 to 20 times over the resting state.

14. Damages of free radicals Free radicals may lead to health problems such as skin aging heart disease cataracts cancer arthritis diabetes

15. Skin aging Free radical damage causes wrinkles by breaking down skin collagen, elastin and other proteins in the skin.

16. Free radicals and heart disease Free radicals cause damage to individual cells within the arteries.

17. Oxidized LDL(low density lipoprotein) LDL itself is harmless. Only when oxidized-- that is, does LDL cause the arterial hardening and clogging that lay the groundwork for heart attack and stroke.

18. Free radicals and cancer Free radicals damage DNA causing tumor initiation, promotion & conversion.

19. Cataract A cataract is a clouding of the lens in the eye that affects vision. Free radicals is a major cause of cataract formation.

20. Arthritis is believed to be a disease stemming from an attack of our own T-Cells on our joint membranes and fluids. The T-cells make deadly free radicals to use in attacking enemies like bacteria, viruses, and cancer cells. But when the T-cells make mistakes and attack our own cells, they use the damaging free radicals on us. In arthritis, the chemically reactive free radicals damage the joint membranes and lubricants, resulting in the pain and limited mobility of arthritis. Arthritis

21. Diabetes Free radicals damage insulin-producing “beta cells” in the pancreas causing diabetes.

22. How Antioxidants May Prevent Against Free Radical Damage An antioxidant can neutralize a free radical by donating one of its electrons without jeopardizing its own chemical stability. It is a free radical scavenger and prevents cell damage.

23. An electron circuit to prevent oxidation of cell membrane by antioxidants OPC, Vitamin C & E.

24. Isotonix OPC-3 Red wine extract, pine bark, isoflavonoids, bilberry and grape seed extract are the strongest known antioxidants. 20 – 50 times more effective than vitamin C and vitamin E respectively, at neutralizing oxygen radicals

25. Improves skin smoothness & elasticity Strengthens capillaries, arteries and veins Improves circulation and enhances cell vitality Reduces capillary fragility and improves resistance to bruising and strokes Reduces the risks of phlebitis( a clot in the vein) Reduces edema and selling in the legs Reduces varicose veins Reduces restless legs syndrome Improves visual acuity Helps improve sluggish memory Reduces the effects of stress Improves joint flexibility and reduces inflammation caused by arthritis and sports injuries

26. Administration of OPC-3 Dosage Take on an empty stomach and wait 10-15 minutes before eating or drinking. Loading dose – For the 1 st 7 days, take 1 white capful per every 75 pounds of body weight. OPC-3 is non-toxic. Those with physical challenges, continue the loading dose for up to 30 days before shifting to a maintenance dose. For preventative health measures, a maintenance dose is considered to be 1-2 capfuls of OPC-3. I white capful contains 75 mg of active OPC and 50 mg of bioflavonoids.

27. Isotonix OPC-3 the best deliverable system for absorption