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National Heart, Lung, and Blood Institute Cancer Research Opportunities Liana Harvath, NHLBI U.S. Department of Health and Human Services National Institutes.

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Presentation on theme: "National Heart, Lung, and Blood Institute Cancer Research Opportunities Liana Harvath, NHLBI U.S. Department of Health and Human Services National Institutes."— Presentation transcript:

1 National Heart, Lung, and Blood Institute Cancer Research Opportunities Liana Harvath, NHLBI U.S. Department of Health and Human Services National Institutes of Health National Heart, Lung, and Blood Institute

2 Stem Cell Transplantation Stem Cell Sources –Cord blood –Bone marrow –Peripheral blood transplantation –Ex vivo expansion Immune Reconstitution

3 Transfusion Medicine and Cellular Therapies - Dendritic cell vaccines - Plasmid DNA cell priming - T-cell adoptive immune therapy - Blood product usage - Hematopoietic growth factors

4 Stem Cell Biology Novel Approaches to Enhance Animal Stem Cell Research [PA-02-147] –For R01 or R21 grants Human Embryonic Stem Cell Research –Competitive supplements [PAR-03-063] –Training initiatives –Infrastructure enhancement awards

5 Thrombosis and Cancer Role of platelets/activated platelets in tumor growth, metastasis and angiogenesis Procoagulant and angiogenic properties of tumor cells Role of fibrinolytic and coagulation proteins in tumor growth and metastasis

6 Pre-Cancerous Conditions Mechanisms involving susceptibility to cancer in pre-cancerous conditions such as: –Myelodysplastic Syndromes & Myeloproliferative Disorders –Fanconi Anemia –Diamond Blackfan Anemia Drug-induced carcinogenesis of the blood.

7 Contact Information Liana Harvath, Ph.D. Deputy Director Division of Blood Diseases and Resources NHLBI, NIH Bethesda, MD 20817 Email: HarvathL@nhlbi.nih.gov Phone: 301-435-0063 FAX: 301-480-0868


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