1. SB2a Build DNA using the Nucleotides HH HH H HH H H Type Your Name Here

2. Process SB1ab ● Why is DNA copied to make more DNA and copied to form the new nucleic acid called RNA? ● Complete the key for the nitrogen bases for your DNA Model ● Blue = guanine ● Green = ● Red = Adenine ● Purple =

3. 1. Copy and paste your DNA from Slide 1 onto this slide in the blank area below 2. Arrange the DNA nucleotides so that it is unzipped or pulled apart without the DNA helicase molecules (scissors) present. 3. Leave enough room in between the top and bottom DNA strand to place the RNA nucleotides. 4. Copy and paste the RNA nucleotides next to the bottom DNA strand on this slide to represent the process of transcription. 5. Place a hand over each RNA nucleotide to symbolize the enzyme RNA Polymerase that is making the RNA strand. 6. If you need more of a particular RNA nucleotide just copy it and paste it as needed.

4. Record the bases from left to right on your new mRNA molecule for just the first 9 bases DNA base sequence ProcessmRNA codon ProcessAmino acid

5. Conclusion 1: Complete the diagram below using (click and drag) the words provided

6. Process SB1ab ● What enzyme does the hand represent when you made DNA? ● What enzyme does the hand represent when you made RNA? ● Where does DNA Replication take place? ● Where does transcription take place in a cell?

7. Process SB1ab ● What process were you simulating by looking up the mRNA letters (codon) to find the amino acids? ● Where does this process occur in the cell? ● What form of RNA is responsible for picking up the amino acids from your table to begin building your protein?

8. Conclusion 2: Once the proteins are produced on the ribosomes.... ● Where do they go to be refined? ● What organelle picks them up for packaging and distribution? ● Label Me

9. Conclusion 3: ● Compare DNA and RNA nucleotides ● Compare the shape of DNA and RNA ● Compare the functions of DNA and RNA

10. Applications ● How is DNA like a filing cabinet (Hint: Read standard SB2b)? ● Make an analogy between building a house and building a protein. Be sure to include all words provided from the diagram slide.