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Figure 1 AB 0.1 0.2 0.3 Liver TG (µg/µg prot) PPAR # C 50 100 150 200 Liver Mac1 staining (cells/mm²) +/++/--/- PPAR D NS Plasma TG (mg/dL) +/++/--/- PPAR.

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Presentation on theme: "Figure 1 AB 0.1 0.2 0.3 Liver TG (µg/µg prot) PPAR # C 50 100 150 200 Liver Mac1 staining (cells/mm²) +/++/--/- PPAR D NS Plasma TG (mg/dL) +/++/--/- PPAR."— Presentation transcript:

1 Figure 1 AB 0.1 0.2 0.3 Liver TG (µg/µg prot) PPAR # C 50 100 150 200 Liver Mac1 staining (cells/mm²) +/++/--/- PPAR D NS Plasma TG (mg/dL) +/++/--/- PPAR 200 400 600 Plasma TC (mg/dL) +/++/--/- PPAR 400 800 1200 1600 NS +/++/--/- # NS 250

2 20 40 60 80 100 120 CON FF *** +/++/--/- PPAR Plasma TC (% of control) *** A 20 40 60 80 100 120 140 160 180 +/++/--/- PPAR B * * Plasma TG (% of control) Figure 2 20 40 60 80 100 120 +/++/--/- PPAR ** CON FF Liver TG (% of control) ### # # CON FF C

3 Figure 3 B 50 100 150 200 250 300 *** CON FF +/++/--/- PPAR Relative VLCAD mRNA expression ### C 50 100 150 200 250 300 350 +/++/--/- PPAR Relative LCAD mRNA expression *** CON FF ### 50 100 150 200 250 300 350 Relative MCAD mRNA expression D +/++/--/- PPAR *** CON FF ### A 50 100 150 200 250 300 350 Relative FAT mRNA expression +/++/--/- PPAR *** CON FF ###

4 Figure 4 A Liver Mac1 staining (% of control ) CON FF 20 40 60 80 100 120 140 * +/++/--/- PPAR PPAR +/+ CONPPAR +/- CONPPAR -/- CON PPAR +/+ FFPPAR +/- FFPPAR -/- FF B # # 50 100 150 200 250 20 40 60 80 100 120 140 160 *** 20 40 60 80 100 120 140 * C *** CON FF Relative ICAM-1 mRNA expression +/++/--/- PPAR D E +/++/--/- PPAR Relative VCAM-1 mRNA expression CON FF +/++/--/- PPAR Relative MCP-1 mRNA expression CON FF # ### # # # ##

5 Lesion area (mm²) +/++/--/- PPAR ### 0.1 0.2 0.3 0.4 ### *** * 0.5 + + + + + + + - + + + + + - - - - + - + - + + - + + PPAR +/+ CONPPAR +/- CONPPAR -/- CON PPAR +/+ FFPPAR +/- FFPPAR -/- FF Mouse1 Mouse2 Mouse3 Mouse4 Mouse1 Mouse2 Mouse3 Mouse4 A Figure 5 B C DE PPAR +/+ CONPPAR +/- CONPPAR -/- CON PPAR +/+ FF PPAR +/- FF PPAR -/- FF PPAR +/+ CONPPAR +/- CONPPAR -/- CON PPAR +/+ FF PPAR +/- FF PPAR -/- FF PPAR +/+ CONPPAR +/- CONPPAR -/- CON PPAR +/+ FF PPAR +/- FF PPAR -/- FF

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