1 Women & Heart Disease Julia C. Orri, Ph.D. Biol. 330 November 21, 2006.
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1 Women & Heart Disease Julia C. Orri, Ph.D. Biol. 330 November 21, 2006
2 Objectives List the trends in heart disease for women Name the risk factors for CAD Define atherosclerosis, MI Compare MI signs between men and women Explain gender differences in heart disease Describe strategies to decrease CAD risk in women
3 233,886 41,566 67,894 American Heart Association, 2006 Deaths From Breast Cancer, CAD, and lung Cancer (2003)
4 Women & CVD Only 13% of women in America believe that CAD and stroke are the greatest health threats to women.
26 What’s your diagnosis? Stella, aged 68 Symptoms Sleep disturbance Unexplained fatigue SOB Indigestion/nausea Pain in back and high chest
27 The Female Heart 38.2 million women have CVD Silent MI more common Atypical chest pain Delayed diagnosis Underutilized prevention & research
28 Female Heart (con’t) 45 million women older than 50 yr Smoking cessation rates declining slower than among men Abdominal obesity 3-7x in CAD risk if diabetic
More visceral abdominal fat (light) = greater health risk
30 Female Heart (con’t) Worse prognosis for women with CAD than men Women had 2x in-hospital mortality rate Age, size of coronary arteries, severity of sickness at presentation Fatality rate
31 Take-Home Message Women have worse prognosis and die more often than men after MI or bypass CAD is largely preventable Major emphasis on lifestyle modifications: smoking cessation, regular PA, maintenance of healthy weight, lipid lowering therapy