1. Catalyst Questions  1. What is the dermis directly below?  2. what is the dermis mainly made of?  3. What are the two structures that separate the dermis from the epidermis?  4. What does the hypodermis generally have a lot of?  5. What is the function of the hypodermis?

2. Let’s Review…  1. Directly below the epidermis  2. it is mainly composed of collagen but also contains reticular fibers, fibroblasts, and other fibrous connective tissue cells  3. The papillary and reticular layers  Papillary is a thin zone of areolar tissue (allows for mobility of leukocytes)  Reticular layer of the dermis is deeper and much thicker  It consists of dense, irregular connective tissue.  4. The hypodermis is mainly composed of adipose tissue which serves as energy reservoir and thermal insulation.

3. Class Updates…  Review day on Wednesday August 24th, plus in class project!  TEST NEEDS TO BE TAKEN BY TUESDAY OR YOU WILL RECEIVE A ZERO  Short test on the integumentary system will be on Friday, 26 th !

4. Review Sheets  A completed review sheet will be worth +10 on the exam.  There was a strong correlation for those that completed the review sheet and their score on their exam.

5. Making Skin Diagrams!  Done with partners  Use the puzzle pieces provided  Use color, label each and describe the functions!  You have 25 minutes, I will set a timer and it will be collected for a grade.

6. Skin Conditions/Diseases

7. SWBAT  Identify 7 different uncommon skin diseases and relate it to their knowledge of the integumentary system.

8. 1. Argyria: Blue Skin  Caused by the ingestion of silver  It affects the dark pigments of skin and the sun decomposes the silver into silver sulfides  It also affects the organs  It is permanent but laser treatment has been used to some success  Most popular case includes an individual named Paul Karason who drank 10 ounces of silver a day to cure his arthritis.

10. Epidermodysplasia Verruciformis  Abnormal susceptibility to human papillomavirus (HPV)  Is asymptomatic in most individuals  Results in a growth of scaly macules (warts) and plaques, particulary on the hands and feet.  No serious treatment though can be surgically removed to some success

12. Hypertrichosis: Human Werewolf Syndrome  Causes excissive hair growth in places that hair does not usually grow  Can present all over the body or only in specific locations  Some are born with the condition while others develop it later in life  No cure, even with laser treatment

15. Blaschko’s Lines  Strange stripes all over the body  Extremely rare  Neither specific disease nor predictable syndrome of a disease  Blaschko’s lines are invisible pattern built into human DNA  May be linked to inheritance or acquired disease of the skin or a mucosa manifest themselves in to patterns creating visual appearance of stripes  The pattern varies from patient

17. Vitiligo: white patched skin  The skin pigments (melanocytes) get destroyed  Causes white patches to appear on the skin  Patches also show up in the mucous membranes and retina of the eyes  The exact cause is still unknown  Maybe caused by a combination of auto-immune, genetic and environmental factors.  Treatment includes steroids, UV light, and creams

19. Tungiasis  Fleas burrow into the skin and lay eggs which causes skin inflammation, severe pain, itching, and lesions at the site of the infection.  Skin infestation of the Tunga penetrans flea  Found in tropical parts of Africa, Caribbean, Central and South America.  The disease is an epidemic in Nigeria, Trinidad, and Tobago  Secondary infection can cause death  Surgical extraction followed by treatment with antibiotic

21. Dermatographia: overly sensitive skin  AKA skin writing  Overly sensitive to minor injuries; even light scratches  The immune system exhibits hypersensitivity; that releases excessive amounts of histamine  Which causes capillaries to dilate and welts to appear  The marks usually disappear

23. EXIT TICKET:  Chose one the skin diseases discussed today and write at least FOUR complete sentences describing it.