2. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Performance Driven Planning : Trends and Customer Success Stories CON 8255 Plan to succeed Customer-Centric. Responsive. Aligned. Vijay Pillarisetti, Director, Product Management, Oracle Value Chain Planning Michael Vigarino, Director, Technical Operations, Bio Marin Vikas Bansal, Advisor, TEK Systems September 30, 2014 2

3. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Safe Harbor Statement The following is intended to outline our general product direction. It is intended for information purposes only, and may not be incorporated into any contract. It is not a commitment to deliver any material, code, or functionality, and should not be relied upon in making purchasing decisions. The development, release, and timing of any features or functionality described for Oracle’s products remains at the sole discretion of Oracle. 3

4. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Agenda 1 2 Current Challenges – Scalability and Need for Better Insights IMPDP: New In-Memory based high-performance architectures APCC: Richer Operational Reporting Capabilities Q & A 4 3 4

5. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Scalability Challenge 5 Global Supply Chains Extended Enterprise Planning High volume, configurable products Response Times Planning Cycles Real-time Operational Reports

6. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Performance Driven Planning Parallel Execution RAC Support Set based Processing Smart Scan Flash Cache From 366 to 127 minutes Hardware: Exadata X3-2 ½ rack; Exalogic ¼ rack, OS: OEL6 * 88 12c In-Memory DB

7. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Richer Operational Reporting End Item based analysis Sorted by SC Bill structure Total Demand Fulfilled Conditional Formatting

8. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Richer Operational Reporting All Order Details Drill down from Build Plan based on End Item In-line navigation to edit/release directly from here

9. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Richer Operational Reporting All Upstream exceptions for an End Item Drill-down from Build Plan based on End Item

10. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Richer Operational Reporting Full Pegging Details (no intermediate levels) Drill-down from Build Plan based on End Item

11. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Richer Operational Reporting Scorecards using fully configurable Performance Tiles Quick summary of Plan health and all key exceptions

12. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Richer Operational Reporting Custom hierarchies Custom attributes Out-of-box integration with Demantra for all custom hierarchies

13. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Richer Operational Reporting Custom hierarchies Custom attributes Out-of-box integration with Demantra for all custom hierarchies

15. O RACLE A DVANCED P LANNING C OMMAND C ENTER I MPLEMENTATION AT B IO M ARIN P HARMACEUTICAL

16. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Safe Harbor Statement This non-confidential presentation contains ‘forward-looking statements’ about the business prospects of BioMarin Pharmaceutical Inc., including potential future products in different areas of therapeutic research and development. Results may differ materially depending on the progress of BioMarin’s product programs, actions of regulatory authorities, availability of capital, future actions in the pharmaceutical market and developments by competitors, and those factors detailed in BioMarin’s filings with the Securities and Exchange Commission such as 10-Q, 10-K and 8-K reports.

17. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Agenda: BioMarin at a Glance Background Summary Oracle Footprint Business Challenges Benefits of APCC Deployment APCC Framework Architecture Commonly used KPIs Lessons Learned Justification for Custom Extensions Sample Reports Review Project Team Structure Implementation Partner

18. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. BioMarin at a Glance BioMarin is a publicly traded (BMRN), multinational biopharmaceutical company, headquartered in Novato, CA specializing in providing innovative first-to- market therapeutics to patients with rare genetic diseases. ~1350 employees world-wide with operations in over 20 countries Manufacturing Facilities on two continents 4 Commercial Products: Total 2012 revenue: $510 M* Naglazyme ® for MPS VI Aldurazyme ® for MPS I Kuvan ® for PKU Firdapse™ for LEMS (EU) Expansive Pipeline & Development VIMIZIM ® for MPS IVA PEG-PAL for PKU New IND candidates in development Ongoing business development efforts *Financial information per BioMarin press release issued Jan 2013 ** Projected non-GAAP net income is calculated in accordance with GAAP but excludes non-cash stock compensation expense, nonrecurring material items and the tax effect of the adjustments

19. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Project Background BioMarin had previously deployed the following Oracle Products: o Oracle Core EBS modules, Advanced Supply Chain Planning o Demantra Demand Management o Oracle Financial Analytics, Supply Chain and Order Management Analytics, Procurement and Spend Analytics, Manufacturing Analytics, Human Resource Analytics The primary goals for the APCC deployment where: Increase speed of ROI for above mentioned Oracle modules Increase visibility to Planning Data (Transactional & Master) Monitoring overall health of planning processes via APCC KPIs BioMarin deployed APCC in the following three phases: o Phase I (Proof of Concept) o Phase II (User Requirements Specification) o Phase III (Development and Implementation)

20. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. ERP Systems Footprint - Oracle EBS R12.1.3 Technical Operations (MFG, Supply Chain, Quality)Finance Supply Chain: ASCP/MRP Production Scheduler** Demantra (Forecasting, S&OP) Order Management/Distribution (OM)+ OPSM (Serialization & e-Pedigree)+ EDI (Orders, Requests, Shipments)+ EDI for Ship Confirmations Global Trade Management+** Procurement: Oracle Purchasing+ i-Procurement i-Vendor** i-Exchange i-Supplier** Materials Management: Inventory Management (INV)+ Mobile Devices via MSCA (barcode guns)+ WMS (Warehouse Management Systems)** MES for OPM (Weigh & Kitting)+ Manufacturing/CMO: Oracle Process Manufacturing (OPM)+ Mobile Devices via MSCA (barcode guns)+ MES for OPM (Buffer & Media)+ Manufacturing Operations Center (MOC)** Oracle Process Quality – OBM2+ MES for OPM (Purification) Quality Management: Oracle to SQL LIMS Interface (Custom)+ Oracle Process Quality (Nonconformances)+ Cash Management: Accounts Receivable (AR) Cash Management (CM) Accounts Payable (AP) Accounting: General Ledger (GL) EDI - Invoicing Asset Management: Fixed Assets (FA) Oracle Projects** Cost Management: Oracle Process Manufacturing (OPM Costing) +GMP Functionality **Not yet Implemented in Novato Analytics/Reporting: OBIEE – Inventory, Finance, Supply Chain/APCC/SC Analytics, Spend Analytics, APCC, Manufacturing Analytics Endeca – Online, real-time, integrated reporting**

21. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Challenges driving APCC implementation Two weeks of manual data collection for monthly planning reports Many data definitions and calculations for the same published metric Use of Excel for storing data leading to lack of single source of truth ASCP Horizontal Plan provides only limited visibility and flexibility ASCP does not provide a consolidate view of plan recommendations Limited view into inventory projections leading to excessive inventory Lack of point-in-time data resulting in inability to compare snapshots Limited view of dependent demand which drives MRP output Difficulty comparing revisions to the same period in forecast, over time Challenge consolidating disparate data to derive Forecast Accuracy

22. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Realized & Expected Future Benefits Realized Benefits: Single source of truth for both localized and global planning data 24x7 access to KPIs, summary, and drilldown reporting via web Reports enabling all-inclusive, flexible views of horizontal plan Federated reports using transactional and planning system data Enabled KPI creation of Months on Hand (MOH) of inventory Expected Future Benefits: Increase in overall planning data visibility leading to: Optimized planning strategy to supply forecasted demand Optimized target Inventory levels and MOH requirements Decreases in expired inventory Increased effectiveness of plan review meetings Compare historical plans to current plan to monitor effectiveness Improvement in visibility into Master Production Schedule (MPS)

23. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. APCC Architecture using Oracle Products Demand Management ASCP o Metrics o Hierarchies o KPIs o Dimensions o Dashboards o Reports o Conditional Alerting o Guided Navigations Operational Data Planning Server Planning Data APCC MVs Plan Archives EBS Collection Program Publish O B IE E Legend: APCC Component

24. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Common KPIs and Metrics enabled by APCC Consensus Forecast Dependent Demand Actual Sales Forecast Accuracy On Hand Inventory Supply Projected Beginning Inventory Projected Ending Inventory Months on Hand (MOH) Manufacturing Org, Distribution Centers and Warehouses Work Orders Plan Orders Planning Engine Recommendations

25. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Lessons Learned Distinguish “Make” from “Buy” orgs to eliminate double counting of Planned Production Order and Planned Material Transfer Differences in planning periods (Calendars) can cause significant data mismatches between Forecasting system and ASCP. Example: Monthly buckets in Forecasting System and 4-4-5 buckets in ASCP Inaccurate or limited use and/or maintenance of ASCP plans causes APCC output to be misstated, and makes root cause analysis difficult. If you plan to use APCC, ensure your ASCP environment is being fully utilized and all plans are being appropriately managed. Master Data Setup – Item Categories, Calendar, UOM conversions, etc have a huge impact on APCC output and aggregation calculations. It is important to find commonality within the master data to allow for desired aggregate and consolidated reporting Schedule the runs of the EBS data collection and Archive Plan Summary programs It may be good practice to implement APCC in phases, where phase 1 is core reporting which seems to be the biggest “bang for the buck”. Then additional phases can follow based on need, including: Scenarios, Activities, etc

26. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Overview and Justification of Developed Extensions Integrated Oracle BI Apps with APCC for measuring Forecast Accuracy Reason: Shipped Sales Orders don’t get collected into ASCP Benefit: Invoiced Sales in Oracle BI Apps helped derive Forecast Accuracy Customized APCC to be able to view quantities in user selected UOM Reason: Different items may have different standard UOMs Benefit: Ability to get consolidated view of all items in a Product Family Modeled MSC_ORDERS_V (Combination of MSC_SUPPLIES and MSC_DEMANDS) into APCC Reason: Plan archive may have time lag in comparison to Current data Benefit: Enabled Real time view of the plan data

27. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Production Plan Screenshot from APCC* * Data in the screenshot manipulated to preserve confidentiality

28. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Plan Recommendations Screenshot from APCC* * Data in the screenshot manipulated to preserve confidentiality

29. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Months on Hand Screenshot from APCC* * Data in the screenshot manipulated to preserve confidentiality

30. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. Project Team Resources & Responsibilities Project Team RoleAreaResponsibilities Technical ArchitectDiLyticsTechnical Delivery; Solve Technical Issues; Lead Technical Team APCC Lead DeveloperDiLyticsDevelop and Implement APCC solution Demantra SMEITSolve / assist Technical Issues ASCP SMEIT Solve / assist Technical Issues Project LeadProject Mgt Complete Project Management; Lead Project Team; Report to Project Oversight; System Owner Approvals Team Member / SMESupply Chain PlanningDevelop URS; Perform UAT; Perform PQ; Develop Process Flows & update SOPs Team Member / SMESupply Chain PlanningDevelop URS; Perform UAT; Perform PQ; Develop Process Flows & update SOPs Team Member / SMESupply Chain PlanningDevelop URS; Perform UAT; Perform PQ; Develop Process Flows & update SOPs

31. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. DiLytics Contact Information: Shyam Panda, Oracle Practice Head Email: spanda@dilyticsinc.comspanda@dilyticsinc.com Phone: 510-456-5605  BioMarin selected DiLytics as the APCC implementation partner  Key reasons for selection:  They had previously worked with us on other OBIEE initiatives  They are an Oracle Gold Partner  Strong Oracle connections including ex-Oracle personnel  Demonstrated knowledge of OBIEE front and back-end functionalities including:  Oracle BI (OBIEE)  Data Warehousing  ETL Technologies  Solid understanding of federated reporting across multiple systems

32. Copyright © 2014 Oracle and/or its affiliates. All rights reserved. THANK YOU

33. Oracle Enterprise Applications & Analytics APCC – Extensions Presented By Vikas Bansal

34. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 34 BusinessBusiness Information Technology Services Company Over 29 years of experience 100+ locations in the U.S., Canada, India, and Europe Global Delivery Centers - US, Canada, and India Providing Services to Over 5,500 Global Clients Services 90% of the Fortune 100 CompanyVertical market focus Over 30,000 Technical Consultants 600 + dedicated resources on Oracle BI $ 3+ Billion USD Flexible Engagement Onsite, Onshore, Nearshore, Offshore Parent Company Allegis Group ($8.3 billion in revenue 2012) Global Services 2012 revenue: $380 million Oracle Platinum Partners & Only Co-Development Partner PresencePresence Customer Profile Co-DevCo-Dev FinancialsFinancials Company Overview

35. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 35 Oracle VCP - Co-Development Partner Co-Dev – Architecture, Design, Development, Early adopter programs, Deployments Over 300+ Oracle BI implementations VCP expertise Largest APCC implementation VCP Product Development EBS/FMW expertise

36. Typical APCC Extensions

37. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 37 Extension Areas  Core Product – Hierarchies, Attributes, Performance, Drill downs  Planning Analytics compared to near real time actuals as they happen  Integration with DW (OBIA)  Big Data – MES, PLC, Online data  Mobility – for executives and line managers

38. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 38 Pre-Seeded vs Custom Hierarchies Planning Facts: Supply, Demand, Inventory, Capacity, KPIs, Exceptions, Cost, … Trading PartnersInternal OrgsItemTime Customer Zone Org Subinventory Operating Unit Fiscal Period Supplier Site Customer Site ABC Class Product Category Resource Department Resource Group Item Product Family Project Task Project Planning Group Day Month Week Quarter Year Mfg Period Alternate Product Hierarchy Customer Hierarchy GL/ Cost Center Hierarchy Product Manager Hierarchy Custom Hierarchies ABC Code

39. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 39 Increased Granularity for Reporting Plan Org Item Time Order # Component Data Collection at the increased granularity level compared to out of the box fact tables designed

40. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 40 Extend Pre-Seeded Attributes Items Item Attributes Customer Customer Attributes Supplier Supplier Attributes Demand Order Attributes Planning Instance EBS Instance APCC generally renders reports from planning instance. Customized reports obtain data from both Planning and Source instance.

41. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 41 Cross Functional Reporting Planning Instance Data Warehouse Instance APCC with OBIA Supply Exceptions monitored against past supplier performance Demand Exceptions along with Customer 360 Planning analytics – comparing plan to actuals Considerations Federation vs ETL Conformed Dimensions Reference data keys Data might be out of sync Release cycles

42. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 42 Mobility

43. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 43 Mobility

44. © 2014 TEKsystems Global Services ® - OEAA Division – Confidential Slide 44 Mobility

45. Oracle Partnership