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July 15, 201010:00 – 11:00 Introduction to Clinical Research: Research Funding and Career Development Michael B. Amey Associate Dean Office of Research.

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Presentation on theme: "July 15, 201010:00 – 11:00 Introduction to Clinical Research: Research Funding and Career Development Michael B. Amey Associate Dean Office of Research."— Presentation transcript:

1 July 15, 201010:00 – 11:00 Introduction to Clinical Research: Research Funding and Career Development Michael B. Amey Associate Dean Office of Research Administration

2 July 15, 201010:00 – 11:00 Research Funding and Career Development Sources of Medical School Revenue Primary Research Sponsors Kinds of Support Primary Initial NIH Grant Types Where to find NIH Information Success Rates Institutional Resources Usual Sequence

3 July 15, 201010:00 – 11:00 Research Funding and Career Development Sources of Medical School Revenue

4 July 15, 201010:00 – 11:00

5 July 15, 201010:00 – 11:00 Research Funding and Career Development Primary Research Sponsors

6 Sponsored Project Sources Johns Hopkins School of Medicine July 15, 201010:00 – 11:00

7 July 15, 201010:00 – 11:00

8 July 15, 201010:00 – 11:00 Primary Sponsor Types Federal (79%) –NIH provides the majority of the federal support –NSF is less than 1% –PHS and other Federal are each about 2%

9 FY 2009 NIH Awards Medical School Rank RANKSCHOOL$(Millions) 1Johns Hopkins435 2UCSF409 3Penn369 4Washington Univ358 5Yale323 6Duke322 7Univ Of Michigan319 8Pittsburgh316 9Univ of Washington279 10UCSD287 10:00 – 11:00 July 15, 2010

10 10:00 – 11:00 Primary Sponsor Types Other (15%) –Disease Specific (small grants and fellowships) –Foundations (usually targeted) –State and Local Government (service and demonstration) –Subcontracts from peer institutions

11 July 15, 201010:00 – 11:00 Primary Sponsor Types Commercial (6%) –Evaluation of Products –Development of JHU inventions –Some collaborative research

12 July 15, 201010:00 – 11:00 Research Funding and Career Development Kinds of Support

13 July 15, 201010:00 – 11:00

14 July 15, 201010:00 – 11:00 Kinds of Support Gifts –No benefit to donor –Can restrict purpose –No specified project

15 July 15, 201010:00 – 11:00 Kinds of Support Grants (assistance for a specified project) –Fellowships –Training Grants –Career Development Awards –Research Projects –Program Project and Center Grants

16 July 15, 201010:00 – 11:00 Kinds of Support Cooperative Agreements (federal assistance with program control) –NIH Multi-Center Clinical Trials Contracts (acquisition of materials or services) –Defines a deliverable material or service –Federal are usually cost-reimbursement –Commercial clinical trials usually fee based

17 July 15, 201010:00 – 11:00 Research Funding and Career Development Primary Initial NIH Grant Types

18 July 15, 201010:00 – 11:00 Primary Initial NIH Grant Types F 32 Post-doctoral Fellowship (537 awards in '09) Career Development Awards –K (01-02) Mentored/Independent Research Scientist Award (144/26 awards in '09) –K 08 Mentored Clinician Scientist Development Award (221 awards in '09) –K 23/24 Mentored/Mid-Career Patient Oriented Research Career Development Award (227/41 awards in '09) –K 99 NIH Pathway to Independence Award (204 awards in '09)

19 July 15, 201010:00 – 11:00 Primary Initial NIH Grant Types Research Project –R 01 Research Project Grant – usually Investigator Initiated (3,601 new awards in '09) –R 03/21 Small/Exploratory & Development Awards (543/1,423 competing awards in '09)

20 July 15, 201010:00 – 11:00 Research Funding and Career Development Success Rates

21 July 15, 201010:00 – 11:00

22 July 15, 201010:00 – 11:00 NIH Award Rates Initial Grant Mechanisms FY 2008

23 R01-Equivalent grants Applications, awards, and success rate s July 15, 201010:00 – 11:00

24 R01-Equivalent grants, New (Type 1) Success rates, by career stage of investigator July 15, 201010:00 – 11:00

25 Research Career Development Awards Number of entry-level awards July 15, 201010:00 – 11:00

26

27 July 15, 201010:00 – 11:00 Research Funding and Career Development Institutional Resources

28 July 15, 201010:00 – 11:00 Institutional Resources Clinician Scientist Award Clinical Research Centers Fund for Medical Research

29 July 15, 201010:00 – 11:00 Institutional Resources Clinician Scientist Program –To protect research time of promising young clinical faculty –Application – draft, submitted or already awarded proposal to a peer review sponsor, Ltrs from Dept. Director & 2 others and interview (due Nov and April 1 st ) –Reviewed by a senior faculty committee representing basic and clinical disciplines

30 July 15, 201010:00 – 11:00 Institutional Resources Clinician Scientist Program –Instructor or Assistant Professor who is an active physician clinician with excellent potential for external awards (is/has completed research training) –Provides up to $80/yr for a max of 2 yrs to support unfunded research effort up to 75% (max when holding an award >$50K is a CSA of $40K)

31 July 15, 201010:00 – 11:00 Institutional Resources Clinical Research Centers - CTSA –Provides patient care costs for investigator initiated clinical research approved by each centers peer review committee –Funded by NIH grants from NCRR

32 July 15, 201010:00 – 11:00 Institutional Resources Clinical Research Centers (part of the Clinical Translational Science Award - CTSA) –Johns Hopkins has 4 JHBMC JHH –Adult Inpatient (Osler 5) –Adult Outpatient (Carnegie 3) –Combined Pediatric PCRU (Blalock 3) –Pediatric Neuro Imaging (KKI)

33 July 15, 201010:00 – 11:00 Institutional Resources Fund for Medical Discovery –Pilot or matching support for new interdisciplinary/interdepartmental research initiatives that will lead to new extramural support –Requires departmental matching of 25% –Proposals are due Sep, Jan and May 15 th

34 July 15, 201010:00 – 11:00 Research Funding and Career Development Usual Sequence

35 July 15, 201010:00 – 11:00 Usual Sequence Basic Scientist –F32 or NRSA Training grant –K (01/02) Mentored/Independent Research Scientist Career Development Award –Research Project Award (R 01/ R 03/R 21)

36 July 15, 201010:00 – 11:00 Usual Sequence Clinician Scientist –Mentored Clinician Scientist (K-08) or Patient Oriented Research Development Award (K 23) –Clinician Scientist Award –Research Project Grant (R 01, R 03, R 21)

37 July 15, 201010:00 – 11:00 Research Funding and Career Development Sources of Medical School Revenue Primary Research Sponsors Kinds of Support Primary Initial NIH Grant Types Where to find NIH Information Success Rates Institutional Resources Usual Sequence

38 July 15, 201010:00 – 11:00


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