1. Peptic Ulcer By: Allicia Kwakye Miss Tran TPJ-3MO

2. What is Peptic Ulcer  Ulcer occurs in the gastrointestinal tract  It is acidic and very painful  It caused by a spiral shaped bacterium that lives within the acidic area of the stomach  Ulcers can developed or worsened by drugs such as Aspirin.  Peptic Ulcer emerges frequently in the duodenum rather than the stomach.  Duodenum is the first part of the small intestine

3. Diagram

4. The Cause  Chronic inflammation due to the Helicobacter pylori. It colonizes the antral mucosa.  The bacterium can cause a chronically active gastritis. ( type B), resulting in a defect by the  The bacterium can cause a chronically active gastritis. ( type B), resulting in a defect by the gastrin produce by that part of the stomach.   NSAIDs such as ibuprofen penetrates the lining of the stomach and releases substances that damages cells.   NSAIDs also blocks the natural chemicals (Prostaglandins) that helps and repair those cells.   Chronic stress is strongly associated in the risk of developing Peptic Ulcer   A combination of chronic stress and irregular meal time is significant to this risk of developing Peptic Ulcer.   Also spicy food and alcohol is a risk for developing Peptic Ulcer.

5. Diagram

6. Symptoms  Gnawing or burning pain in the abdomen. This occurs between the breast bone and navel, it is often by pass as a “heartburn”.  Bleeding from the Peptic Ulcer. - Is present during vomiting or in the stool - Is present during vomiting or in the stool (black stool).  You may experience these symptoms soon after meals: –Pain –Nausea –Pain that radiates to the back – Unusual weakness –Unintended weight loss

7. Treatment  A combination of antibiotics and acid reducing medication such as: – Proton Pump Inhibitors. –Esomeprazole, –Pantoprazole –Rabeprazole  Antibiotics: –Clarithromycin –Amoxicillin –Metronidazole They all should be take twice per day.