2. depigmentating treatment effective against melanic blemishes

3. MELANIN SYNTHESIS DOPAQUINONE DOPA TYROSINE
dermamelan
Prior to treatment
Melanogenesis is the combined process of physical, biochemical and morphologic skin factors to protect itself against the action of solar radiations.
Melanin synthesis is produced as follows:
MELANIN SYNTHESIS
DOPAQUINONE
DOPA
TYROSINE
Tyrosinase (Cu)
Oxidation
Cyclation
EUMELANINS
PHEOMELANINS

4. effective depigmentation method against stains of melanic origin
dermamelan
Prior to treatment
effective depigmentation method against stains of melanic origin
Dermamelan method is a topical depigmentation treatment.
It is a long term treatment that includes a consultation treatment and the corresponding home maintenance.
Short term action: gets rid of the superficial hyperpigmentation, through a chemical exfoliation.
Long term action: Reversible and no cytotoxic inhibition of the melanogenesis  control and progressive elimination of the melasma manifestations.
It is the number 1 depigmentation treatment in the world. Compatible with any skin phototype.

5. Degreasing solution dermamelan mask dermamelan treatment
Prior to treatment
Effective depigmentation treatment against stains of melanic origin
Degreasing solution
dermamelan mask
dermamelan treatment
1 treatment session
+ home maintenance

6. Degreasing solution dermamelan mask
Pack composition
Degreasing solution
Clean and degrease the skin to ensure a better absorption of the treatment depigmentation substances.
It should be applied in a cabin.
flask of 10 ml.
professional use
dermamelan mask
Mask with active depigmentants. Intensive and integral method against stains of melanic origin of any nature.
Recommendations of use:
Leave for the recommended time according the skin phototype.
Phototypes I and II: 8 hours
Phototypes III and IV: 10 hours
Phototypes V and VI: 12 hours
Jar of 10 gr.

7. dermamelan treatment hydra vital factor k
Pack composition
dermamelan treatment
Home use
Maintenance cream with active depigmentants.
Complements the depigmentation process initiated during the visit.
Recommendations of use:
Apply dermamelan treatment maintenance cream using the 3,2,1 method .
1st 15 days: 3 applications. Morning/midday/night
15 days thereafter: 2 applications Morning/night
From 2nd month onwards: 1 application. Night
(*) During the 1st Phase of the home treatment, avoid exposition to heat sources or direct light.
Jar of 30 gr.
Daily use cream that provides the necessary nutrition and hydration.
hydra vital factor k
Tube of 50 ml.

8. Phase prior to dermamelan treatment
Prior to treatment
Phase prior to dermamelan treatment
Medical record(anamnesis)
All the relevant data will be collected such as , habits, personal or technical (skin type,
lesion types, associated problems) and any factors related to the disorder.  
Personalized diagnosis
In order to adapt the application protocol based on the needs of each patient.
Fill out the informed consent form
Involving the patient on the treatment process, and also at the same time invite them to continue with thehome treatment (fundamental protocol ).
Photographic register
Guaranteing an objetive assessment of the evolution of results
Control visits
It is important to carry out control visits with an adapted periodicity based on the particular needs of each case.

9. Wood light is a light beam emitted by a mercury lamp.
dermamelan
Prior to treatment
CARRY OUT A SKIN ANALISIS THROUGH WOOD LIGHT
Wood light is a light beam emitted by a mercury lamp.
Epidermis melasma : it stands out with the light (dark fluorescence).
dermal melasma : faint/ poor fluorescence.
Mixed melasma : Certain areas are highlighted but not others.
Unapparent melasma: Disappears with the light (V o VI).

10. Dermamelan treatment protocol
Phase 1: preparation
Remove make-up and tone up with hydra milk cleanser and hydratonic.
Phase 2: desengrasar
Apply with a gauze the exfoliating solution, rubbing the forehead, cheeks and central areas on the face.

11. Dermamelan treatment protocol
Phase 3: protect
Protect with mesolips protector the sensitive areas that must not be in contact with the mask.
Phase 4: treat
Apply dermamelan mask with a glove or with a spatula using larger amounts in the more affected areas.
Leave it to work during the recommended time based on the skin phototype.
The exposition time must be between 8 and 12 hours (according professional opinion).
Once the exposition is over, wash off with abundant water.

12. Dermamelan treatment protocol
Phase 5: progressive inhibition
Recommendations of use:
Apply dermamelan treatment maintenance cream using the 3,2,1 method .
1st 15 days: 3 applications. Morning/midday/night
15 days thereafter: 2 applications Morning/night
From 2nd month onwards: 1 application. Night
(*) During the 1st Phase of the home treatment, avoid exposition to heat sources or direct light.

13. Dermamelan treatment protocol
Phase 6: prescribe
Apply the hydra-vital factor k cream indicated to return softness and elasticity.
Apply moisturising sun protection, several times a day based on the luminic exposition.

14. Changes in the skin during the treatment
dermamelan
Changes in the skin during the treatment
Oedema / Eritema
The may be one of the manifestations of the treatment. They are transitory.
Correspond to the expected evolution after this treatment and based on the skin sensitivity and can remain for a few days.
peeling
According to the skin sensitivity, they may present during the home treatment and usually disappears once the moisturising product is fully absorbed.
Ardor / Escozor
This feeling can be mitigated through the systematic application of products that provide and ideal moisturising level.
Feeling of tightness

15. Precautions and contraindications
dermamelan
Precautions and contraindications
Solar erythema (avoid the exposition to radiation UV the previous 15 days).
Pregnancy and breastfeeding.
Dermatological diseases, allergic individuals to any formulation component .
Treatments with isotretinoine , antibiotics, hydroquinone.
Bacterial, viral, mycotic o herpes infection.
It is not advisable to combine it with other chemical exfoliation and/or depilation techniques.
The mask exposition time, will be subject to a professional criteria based on phototype , and skin characteristics and conditions.
In order to extend the results over time, it is essential to complete the home treatment cycle.

16. Cosmetic line with high vitamin C concentration. Contents of pack:
dermamelan
Coadjuvant treatment products for cabin treatment in subsequent sessions .
Cosmetic line with high vitamin C concentration.
Contents of pack:
Energy C serum
Energy C crystal fiber mask
Energy C intensive cream

17. Cosmoceutic line with high concentrations in vegetal stem cells.
dermamelan
Coadjuvant treatment products for cabin treatment in subsequent sessions
Cosmoceutic line with high concentrations in vegetal stem cells.
Contents of pack:
Stem Cell serum re-structuractive
Stem Cell crystal fibre mask
Stem Cell active growth factor

18. proteoglycans ampoules
dermamelan
Coadjuvant products of home treatment
melanogel touch
All types of skins
post-procedure
fast skin repair
All types of skins
post-treatment
Post-treatment
Continous maintenance
Repairing cream with anti-oedema and anti-erythematous properties .
Occasional depigmentation treatmentof stains of melanic origin.
anti-stress face mask
All types of skins
proteoglycans ampoules
Dry and normal skins
post-treatment
post-treatment
Continous maintenance
Continous maintenance
Calming and repairing mask.
Nutritive solution.
moisturising
sun protection
Dry and norma skins
post-treatment
continuous maintenance
Solar facial cream.
Very high protection | SPF50+

19. Coadjuvant products of home treatment
dermamelan
Coadjuvant products of home treatment
Post-treatment
Post-treatment
Continous maintenance
Continous maintenance
Cosmeceutical line with high concentrations of Vitamin C.
Cosmeceutical line with high concentrations of vegetal stem cells.
Post-treatment
Continous maintenance
Cosmeceutical line of whitening and perfectioning action formulated with [meso]white complex®.

20. 1. What is the mechanism of action of dermamelan?
FAQ’s - dermamelan
1. What is the mechanism of action of dermamelan?
Works in non cytotoxic way, inhibiting the production and the transference of the melanin pigments . It produces a chemical superficial exfoliation, allowing the attenuation and /or elimination of the superficial hyperpigmentation on various depths.
2. What feelings is the patient likely to experience during the eight hours of exposition to the dermamelan mask?
The symptoms may vary between individuals, however a light sensation of itchiness or burning and tightness may be felt.
3. What changes may the skin experience the days after the application of the dermamelan mask?

21. 4. Is it necessary to take any precautions during the treatment?
dermamelan
FAQ’s - dermamelan
4. Is it necessary to take any precautions during the treatment?
Besides of being an imperative requirement to avoid post-inflammatory hyperpigmentations, it is essential to use continually a sun protector with high filters, at the light exposition of any nature, because natural and artificial light may stimulate the synthesis of melanin.
If by any work activities you are exposed to direct spotlights, it is necessary to repeat the application of solar protection regularly.
During the first post-treatment week, it is recommended to avoid the following activities:
swimming in pools, sauna, exposition to sources of direct heat and outdoors sports.
5. How long is the home treatment recommended to be for?
It is recommended for a minimum of application of 4 months and can be extended to 9 months based on the evolution of each case.

22. 7. How long does it take to see the result of the treatment?
dermamelan
FAQ’s - dermamelan
6. In which cases is it recommended to supplement dermamelan and depigmentation treatment with tmt system no 7?
Once the treatment with dermamelan is finished, the PROFESSIONAL will assess the possibility of supplementing the depigmentation effect with tmt system No. 7 treatment for those hyperpigmentations which by their deeper location deeper still persist.
7. How long does it take to see the result of the treatment?
As of one month of the application of dermamelan treatment we can see the attenuation of the hyperpigmentation and the eradication of the most superficial ; besides of a visible improvement of the skin, unifying the tone
8. During the 4 months of home dermamelan treatment, ¿Can a technique such as bio-stimulation be used?
Once the once a night application phase is reached, the skin can be treated with any therapy as long it is not photodynamic.

23. contain components that may interfere with the metabolism of the
dermamelan
FAQ’s - dermamelan
9. Can dermamelan treatment be used indefinately after a dermamelan treatment has been conducted?
With the aim of extending the benefits associated with the skin embellishment , it is common to maintain dermamelan treatment indefinitely spacing out its application.
10. Can certain medicines and/or nutritional supllements affect the treatment results?
Many medicines have photo-sensitising effects on the skin; nutritional supplements
contain components that may interfere with the metabolism of the
Melanin synthesis.
The use of either must be considered to predict the efficacy of any depigmentation treatment. Therefore, it essential to collect the all the information through the anamnesis.