1. © 2011 VPH Institute VPH Institute General Assembly 2011 September 28th 2011 – 14.00/18.00 Tanger Building, Room 55.309 Universitat Pompeu Fabra – Barcelona

2. © 2011 VPH Institute Agenda 14:00 – 15:00Peter Hunter (University of Auckland) Description of the statutory process presentation of the statute presentation of Management and of the first Board of Directors 15:00 – 15:30Martina Contin (Manager, VPH Institute) Ratification of the 2012 membership presentation of the services to the members 15:30 – 16:30Marco Viceconti (University of Sheffield) Presentation of the Business plan 2011-2013 Preliminary Budget 2012 Proposal for 2013 membership fees 16:30 – 17:00Nicholas Ayache (INRIA) Presentation of the electoral procedure 17:00 – 18:00Marco Viceconti (University of Sheffield) Presentation of the position on Horizon 2020 2

3. © 2011 VPH Institute VPH Institute statutory process Peter Hunter University of Auckland member of the Board of Directors 3

4. © 2011 VPH Institute Statutory process /1 September 2007 - The origins: the STEP VPH Research roadmap The idea of creating a permanent, no-profit organisation for the VPH initiative was included in the STEP research roadmap. December 2009 - VPH NoE vision and Strategy 2009 This idea was re-proposed and expanded in the STEP roadmap 2009 update entitled “A Vision and Strategy for the VPH in 2010 and beyond” elaborated by the VPH NoE. January 2010 - Public petition Following the mandate of the VPH NoE, a public petition was organised on Biomed Town to verify the support of the VPH community to the creation of this institute. Nearly 300 experts from over 30 countries have signed this petition, clearly expressing their support to this idea. March 2010 - Pro Tempore Board is appointed Nine "probi viri" internationally recognised experts, representing many countries and research sub-domains, were invited to form a Pro Tempore Board, invested with a very limited mandate: to elaborate a draft statute for the Institute, to be submitted to the public discussion. August 2010 - Draft statute open to public revision The draft statute was submitted to public revision. The document was left open for comments for a month. 4

5. © 2011 VPH Institute Statutory process /2 September 2010 - VPH Consensus Meeting in Brussels The draft statute was presented and discussed, and requested changes were factored in version 6 of the draft statute. October 2010 - Call for founding supporting members A public call for founding supporting members for the VPH Institute was sent via the VPH News email channel to over 10,000 unique recipients. Preliminary expressions of interest were received from 18 institutions; of them 10 submitted the formal commitment letter before the deadline, and were invited as Founding Supporting Members. November 2010 – Support actions give mandate to the Institute Replying to a request for clarification, the coordinators of the actions VPH NoE, VPH-FET, and ARGOS, agreed to delegate to the VPH Institute, responsibility for elaborating a formal recommendation on “the continuation of VPH research”. December 2010 - VPH NoE vision and Strategy 2010 In the 2010 update, “A Vision and Strategy for the VPH”, the mission and vision of the VPH institute were defined. 5

6. © 2011 VPH Institute Statutory process /3 March 2011 - Constitution meeting Representatives of the ten founding supporting member institutions met in Leuven (BE) for the Constitution Meeting. May 2011 - Incorporation On May 16th, 2011 the incorporation process was completed; the VPH Institute was then a legal entity. July 2011 – Membership campaign All institutions involved with VPH projects were invited to join the VPH Institute as ordinary members September 2011 – First General Assembly 50 member institutions were invited to attend the first general assembly in Barcelona October 2011 – Presidential Election The first President of the VPH Institute will be elected by its members via electronic ballot 6

7. © 2011 VPH Institute Mission & vision The mission of the VPH Institute is to ensure that the Virtual Physiological Human is fully realised, universally adopted, and effectively used both in research and clinic. The vision of the VPH Institute for the first five years is to realise the VPH to the largest possible extent. To achieve this objective the VPH institute will work to: – Ensure that VPH-related research receives an adequate level of funding all over the world; – Ensure that this funded research contributes with a high degree of synergy to the realisation of the VPH. The vision of the VPH Institute for the following ten years is to make sure that the VPH framework is: – Universally adopted; – Deployed into research and clinical settings in order to produce the highest possible benefits. 7

8. © 2011 VPH Institute Governance rules Governance rules should evolve with the definition of what exactly the Institute is, what scope it has, etc. The Statute was designed as a lightweight document, to make such changes easier: – Statute includes only core principles and legal articles – Minimal structure imposed by the Belgian law – All major procedural rules are defined in Bylaws that can be changed with a simple majority of the General Assembly – Members are invited to make suggestions on how to improve the procedural rules to the Manager – “Decisions regarding the modification of the articles of association are taken only by a qualified majority of two thirds (2/3rd) of the members present or represented”. 8

9. © 2011 VPH Institute Efficiency Vs. democracy Balance efficiency and internal democracy – An alliance of institutions – Supporting members have executive powers – General members have oversight of the executive function of the supporting members – Institutions every year can switch from one role to the other to match their specific strategic interests 9

10. © 2011 VPH Institute Governance 10

11. © 2011 VPH Institute Founding Board of Directors 1.University of Auckland, NZ (Peter Hunter) 2.Universitat Pompeu Fabra, Spain (Alejandro Frangi) 3.INRIA, France (Nicholas Ayache) 4.University of Sheffield, UK (Rod Hose) 5.Università di Roma 4, Italy (Aurelio Cappozzo) 6.KU Leuven, Belgium (Jos vander Sloten) 7.Entelos Inc., USA (Ananth Kadambi) 8.Istituto Ortopedico Rizzoli, Italy (Marco Viceconti) 9.Universidad de Zaragoza, Spain (Pablo Laguna) 10.Osped. Pediatrico Bambin Gesù, CdV (Giacomo Pongilione) 11

12. © 2011 VPH Institute Executive Office 12 Martina Contin (Manager) Marco Viceconti (Executive Director)

13. © 2011 VPH Institute Manager’s report Martina Contin Istituto Ortopedico Rizzoli - Bologna

14. Manager report Ratification of the 2012 membership Presentation of the services to the members

15. Membership and fee status Up to Monday 26th of September: we received: 42 applications From Statute Art 4, Rules for admission –Membership applications shall be submitted to the Board of Directors to be evaluated –If the Board of Directors approves the application, the applicant institution will be asked to pay the membership fee –Upon such payment the applicant institution will receive an un-ratified membership status –This status will last until the decision of the Board of Directors is ratified by the following General Assembly

16. Membership and fee status 2011= no membership fee Formal approval of the membership application by the Board of Directors Ratification of the General Assembly FORMAL VOTE

17. © 2011 VPH Institute Ratification procedure This year: – Only founding members can ratify the first list of members; since these coincide with the members of the Board of Directors, which already approved the list, the ratification is only a formality, a mention in the minutes Proposed procedure from next year: – Existing members will receive the list of new members to ratify one month before the General Assembly – Ratification of the new members will always happen at the beginning of the General Assembly, so that also them do have voting right from then on 17

18. Ordinary Membership 1.Academic Medical Center (AMC), Department of Biomedical Engineering and Physics, Amsterdam, The Netherlands 2.ALMA IT SYSTEM, S.L. 3.ASD Advanced Simulation & Design GmbH 4.Barcelona Digital Technology Centre (Bdigital) Health R&D&I 5.Catalan Agency for Health Information, Assessment and Quality (CAHIAQ) 6.Center for Integrative Biomedical Computing (CIBC), University of Utah 7.Centre for Computer Graphics & Visualisation, University of Bedforshire 8.Centre for Mathematical Medicine & Biology, University of Nottingham 9.CNR National Research Council of Italy - IAC Institute for Computing Application 10.Computational Science, Faculty of Science, University of Amsterdam 11.CREATIS CNRS UMR 5220 INSA - Lyon 12.DePuy CMW 13.Dipartimento di lngegneria dell'lnformazione (Department of lnformation Engineering) / Università Politecnica delle Marche - Ancona Italy, Bioengineering Department 14.empirica Gesellshaft fur Kommunikations und Technologieforschung mbH 15.Erasmus MC Rotterdam, The Netherlands, Department of Radiology and Medical Informatics, Biomedical Imaging Group Rotterdam (BIGR) 16.EURESIST NETWORK GEIE

19. Ordinary Membership 17.European Medical Association (EMA) 18.Foundation for Research and Technology - Hellas (FORTH), Institute of Computer Science (ICS), Computational Medicine Laboratory (CML) 19.Institute for Bioengineering of Catalonia (IBEC) 20.Institute for Human Performance and Rehabilitation (PerfoTech) 21.Institute for Surgical Technology and Biomechanics, University of Bern, Switzerland 22.Institute of Communication and Computer Systems National Technical University of Athens (ICCS-NTUA) 23.Istituto Auxologico Italiano 24.Kings College London, Biomedical Engineering Department, Division of Imaging Sciences and Biomedical Engineering 25.Mario Negri Institute, Biomedical Engineering Department 26.Mechanical Engineering, Rehabilitation and Medical Devices (RAMD), Escola Politecnica Superior D' Enginyeria De Manresa (EPSEM) 27.Noema Life Spa 28.Norwegian University of Life Sciences, Dept of Mathematical Sciences and Technology, Centre for Integrative Genetics (CIGENE) 29.Saarland University, Faculty of Medicine, Department of Paediatric Oncology and Haematology 30.SuperComputingSolutions -SCS- srl

20. Ordinary Membership 31.Section Medical Genomics, Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands 32.Technological Educational Institute of Lamia (TEILAM), Dept Informatics and Computer Technology 33.Università degli Studi di Roma Tre - Dipartimento di Elettronica Applicata 34.Università degli Studi Guglielmo Marconi, Facoltà di Scienze e Tecnologie Applicate,Software Engineering Laboratory 35.UNIVERSITY CAMPUS BIO-MEDICO OF ROME 36.University of Bologna - Department of Electronics, Computer Science and Systems - Cellular and Molecular Engineering Lab - Computational Cardiovascular Physiopathology Unit 37.University of Verona, Department of Informatics, Robotics Labs "Altair" 38.Vrije Universiteit Brussel (VUB), Department of Experimental Anatomy (EXAM), Brussels - Belgium 39.VTT Technical Research Centre of Finland 40.Università degli Studi di Pavia - Dipartimento di Matematica - Laboratorio di Elettrocardiologia Computazionale 41.Università degli Studi di Milano - Dipartimento di Informatica 42.CIBER-BBN (Biomedical Research Networking center in Bioengineering, Biomaterials and Nanomedicine)

21. Service to members: Web-site Currently the VPH Institute has a web presence on Biomed Town https://www.biomedtown.org/biomed_town/vphinstitute/ https://www.biomedtown.org/biomed_town/vphinstitute/ This is a temporary solution Next step: website development –The domain has already been bought: www.vph-institute.org www.vph-institute.org –Website: Content Management System based on Plone3

22. Web-site Public area: what everybody can see –Home –About the VPH Institute –Governance –Membership –Documents – News –Upcoming events Private area: managed by a group permission system –Users –Ordinary members –Supporting members –Work-groups –Board of Directors –Board of Trustees

23. Web-site Content Management System based on Plone3 => interactivity: each user can contribute to the website, creating…

24. On-line membership management Member registration: –Each user can specify the name of the member institution through which they claim the VPHI benefits –The registration will have to be confirmed by the delegate of that institution (an automatic email will be generated during the registration submission process) –Once approved, the user gets upgraded to “VPHI member” = > VPHI members will have different benefit than web-site users (i.e.: access to member only information)

25. On-line membership management Membership fee payment: –On-line invoicing generation –Link to on-line invoice –Pay pal facilities, to pay the membership fee via web => The fee payment process will take only few clicks

26. Communication services Internal Communication Creation of official email addreses: –director@vph-institute.orgdirector@vph-institute.org –manager@vph-insitute.orgmanager@vph-insitute.org Creation of email alias to avoid confusion in the communication –Directors (i.e.: directors@vph- institute.org)directors@vph- institute.org –Working groups… Email updates to the VPHI membership on regular basis External communication Production of news and events on the website Generation and distribution of a monthly newsletter to all members and website users Production and distribution of press-release for important topics (Alpha Galileo account, collaboration with freelance science writer)

27. © 2011 VPH Institute Thank you!

28. © 2011 VPH Institute Executive Director’s report Marco Viceconti University of Sheffield 28

29. © 2011 VPH Institute VPH: Definition The Virtual Physiological Human is a framework of methods and technologies that once established will make possible the integrative investigation of human body 29

30. © 2011 VPH Institute What is VPH? Cover all organ systems, all scales. Large-scale research initiative. Started in 2005, > €200m funding, ≈ 200 European institutions, > 2000 researchers International ramifications in USA, Japan, Korea, Australia, China, etc. A network of Excellence, a congress, three special issues on TRS, two books a virtual institute 30

31. © 2011 VPH Institute VPH Institute: rationale “In this scenario there are all the conditions for the VPH to be confirmed a primary research topic for European and member state funding agencies in the next 5-10 years, which will ensure to our universities, institutes, and companies a sustained flow of funding opportunities and chances for further development” The competition between research domains in ensuring that part of this reducing budget is targeted to them is becoming fierce. Ultimately, only those communities that are internally organised, and are capable of projecting to the decision-makers and to the public at large a convincing story on the importance of that research topic will succeed in this competition. 31

32. © 2011 VPH Institute Goals The VPH community needs: – to speak with one voice; – to strengthen the international profile of VPH; – to convince the decision makers that the VPH is the topic to be funded in the forthcoming years; – to consolidate biomedical integrative research as a new foundational topic around which to develop educational curricula, establish scientific journals and international conferences, scientific societies and prizes; – To demonstrate and assess the early VPH technology in clinical settings. 32

33. © 2011 VPH Institute VPH Institute The mission of the VPH Institute … –is to ensure that the Virtual Physiological Human is fully realised, universally adopted, and effectively used both in research and clinic. The status is … –not-for-profit international organisation incorporated in Belgium on March 24 th, 2011, operated by a Board of Directors elected by its members among the those which every year take the status of Supporting Member institutions. 33

34. © 2011 VPH Institute PRESENTATION OF THE BUSINESS PLAN 2011-2013 34

35. © 2011 VPH Institute Institutional objectives Internationalisation and outreach toward neighbourhood communities Lobbying, promotion of the public identity, and communication services Promotion, curation and operation of VPH cyber- infrastructures Provision of targeted services for academic, clinical and industrial members 35

36. © 2011 VPH Institute Membership’s services 2012 On-line services: – www.vph-institute.org: web site with added-value services for members www.vph-institute.org Hosting of thematic work groups: – Work group on “VPH Policy Affairs”, supported by consulting firm specialised in policy communication – Work group on “Bridging Physiome and Systems Biology”: work group aimed to develop a strategy to promote the convergence of Phyisome and Systems Biology – Work group on VPH International: coordination with other no-profit organisations (IUPS, IEEE, EAMBES, etc.) that have work groups on integrative research Dissemination and communication services: – VPH News service: production, concentration and re-distribution of news bites, press releases, and targeted newsletters on all about VPH – VPH Branding: development, promotion, protection of the brand 36

37. © 2011 VPH Institute Future services /1 On-line services: – VPH Portal: public portal with community services and single sign-on for all VPH- related on-line services – Manage access to VPH infrastructures that require moderation, promotion, or pay- per-use fee management – VO resource allocation panels for infrastructural actions Dissemination and communication services – VPH observatory for funding, results, patents, trials – Communication and dissemination services: targeted dissemination programs for projects – Access to specific expertises for funding agencies, policy makers, etc. Industrial affairs – Work group on Standardisation – Assessment and exploitation services: targeted technology assessment programs and development of exploitation activities such as business plans, venture capitals, industrial fairs, etc. 37

38. © 2011 VPH Institute Future services /2 Training and publishing – VPH Training: targeted training activities such as summer schools, one-day professional workshops, etc. on the VPH and its tools. – VPH Congress: organise a biennial scientific conference on integrative research and VPH – VPH journals: edit one or more publications dedicated to the VPH – VPH strategic consensus meeting and road-mapping: maintain a set of research and technological development roadmaps that survey the sector and draft the directions of development Professional services – Facilitation services for consensus meetings, road-mapping activities, technical discussions in large consortia, community building, etc. – Coordination services: consultant services for proposal writing and project management in the domain of integrative research and VPH – Hosting for other no-profit organisations: use to the ICT and management infrastructure to host secretary services for other no-profit organisations 38

39. © 2011 VPH Institute Role of Institute Suggestions from the floor on the role and activities the institute should carry out 39

40. © 2011 VPH Institute Membership: expansion plan Target #1: all institutions partner of EC-funded VPH projects – We estimate that there are roughly 200 institutions involved with EC-funded VPH projects – Manager will list and contact them one by one, as soon as consortia are made public – All members involved in these projects should evangelise the rest of the consortium Target #2: VPH-like European national projects and non-EU projects – Manager will contact members from each country or world region to ask support in order to identify such projects and their coordinating institutions. Non-EU include the Japanese Systems biology COE, the grantees of the IMAG agencies in USA, etc. – Support to the formation of local chapters, such as VPH-NL Target #3: Any other interested institution worldwide – can be reached through VPH News, Biomed Town, and any other communication channel related to the VPH. A specific membership campaign will designed for these generic channels. 40

41. © 2011 VPH Institute PRELIMINARY BUDGET 2012 41

42. © 2011 VPH Institute Planned expenses 42 2011-20122012-20132013-2014 EXPENSE DETAILS BUDGETED OPERATIVE Salaries and wages€15,000.00€50,000.00€85,000.00 Consultants€38,000.00€35,000.00 Advertising€6,400.00€10,000.00€20,000.00 Travelling€5,000.00€16,000.00 Insurance€1,000.00€5,000.00 Cash reserves€0.00 Total operative expenses:€65,400.00€116,000.00€161,000.00 SERVICE & EQUIPMENT Accounting€5,000.00 Legal€0.00 Other€1,500.00€5,000.00 Total S&E expenses:€6,500.00€10,000.00

43. © 2011 VPH Institute Services 2013-2014 Full-time Manager, part-time Director Policy affairs consultant annual contract PR and Facilitation consultants on demand Full communication services (web, newsletter, press releases, linkedin group, etc.) All institutional travels costs covered Full administrative, legal, and insurance coverage 43

44. © 2011 VPH Institute Income and budget 44 2011-20122012-20132013-2014 INCOME DETAILS BUDGETED Supporting fees€90,000.00 Ordinary fees€0.00€45,000.00€90,000.00 Services€0.00 Total income:€90,000.00€135,000.00€180,000.00 2011-20122012-20132013-2014 SUMMARY BUDGETED Total income€90,000.00€135,000.00€180,000.00 Total expenses€71,900.00€126,000.00€171,000.00 Income less expenses: €18,100.00€9,000.00

45. © 2011 VPH Institute PROPOSAL FOR VPH INSTITUTE MEMBERSHIP FEES 45

46. © 2011 VPH Institute Other similar organisations Quad Cities Prof. Develop. Network€1,500.00 Int. Assoc. of Universities €1,000.00 (sm) ACLS (US council learned soc.)€ 900.00 UK council for international affairs€ 500.00 (sm) CAUCE (Canadian org for cont. educ.)€ 300.00 (sm) ECREA (Communic. Research Assoc.)€ 250.00 College Board USA € 250.00 EDINA UK data centre € 228.00 EAMBES (EU alliance of BME)€ 200.00 46

47. © 2011 VPH Institute Institute membership fee For year 2012-2013 the membership fee are: – Ordinary member institution€ 900.00 – Supporting member institution€9,000.00 Projected income: – 50 member institutions in 2012-2013 – 100 member institutions in 2013-2014 47

48. © 2011 VPH Institute Thank you!

49. © 2011 VPH Institute Board of Trustees: Electoral procedure Nicholas Ayache INRIA member of the Board of Directors 49

50. © 2011 VPH Institute Election: Board of Trustees The Board of Trustees is formed by a President and two financial auditors. The role of the Board of Trustees is to supervise the operations of the Board of Directors, ensuring that such operations do not get into conflict with the interests of the membership at large and does not violate the common law, the legal provisions and the provisions in the Articles of Association. The representatives of all member institutions in good standing elect the Board of Trustees from a list of candidates nominated by the General Members (Note: the term used in the statute is “expressed”; the BoD agreed that the proper interpretation is that candidates can be any person that is nominated by a member organisation). 50

51. © 2011 VPH Institute Delayed elections The original plan was to elect the BoT during this assembly, but: – Many institutions were waiting for their governance to approve the membership Thus, the elections this year will follow this procedure: – Official call for candidatures was circulates on September 12th, 2011; ask copies to Martina. To be eligible you must be the representative appointed by one of the member institutions (i.e. which submitted the application form; only for this year even non-ratified institutions will have voting rights) – The call for candidates will close at 24:00 on September 30th, 2011. This is two days after the General Assembly, giving to uncertain colleagues the possibility to attend the General Assembly, understand better what this means, and then express their candidature in the following two days. – Representatives of member institutions in good standing will receive the email ballot on October 31st, 2011. So in order to exert the right to vote your institution must become a member before that date. – Email ballots will be accepted until November 30th, 2011. So if you are candidate you must ensure that your institution becomes a member before this date. 51

52. © 2011 VPH Institute Public call for candidates The members representatives are invited to express publicly their intention to nominate themselves for the position of President or for that of Financial Auditor Members can also nominate as candidates absent colleagues, so long as they have previously indicated their acceptance to be nominated The Board of Directors will actively seek candidates, and if no candidates are nominated by the General Membership, will seek candidates from the Supporting Membership 52

53. © 2011 VPH Institute By-laws article required Submit to the GA approval a single article: “The mandate of the President and of the Financial Auditors that form the Board of Trustees is two years. The mandate can be renewed for one additional term, for a total of four years” 53

54. © 2011 VPH Institute Thank you!

55. © 2011 VPH Institute Horizon 2020: VPH Institute position Marco Viceconti University of Sheffield 55

56. © 2011 VPH Institute ARGOS We, the academic, industrial and clinical stakeholders of the VPH initiative recommend the European and United States governments: Work together on a common policy to harness outcomes of all VPH-type research efforts toward the creation of a global VPH Cyberinfrastructure, by ensuring that all repositories of data and models, as well as all the methods and technologies developed during these research projects funded by governmental agencies are mutually interoperable. Support the establishment and the operations of an International Multistakeholder Advisory Group responsible of elaborating a collective vision, as well as the minimum set of standards and the technical guidelines that ensure the interoperability and the integratibility of all VPH resources into the global VPH Cyberinfrastructure, to achieve the vision of the Virtual Physiological Human. https://www.biomedtown.org/argos/reception/brief

57. © 2011 VPH Institute Title: Future and Emerging Technologies for the Virtual Physiological Human. Summary: The Virtual Physiological Human (VPH) is framework of methods and technologies that, once established, will allow the integrative investigation of the human body, seen as a whole. While for some specific clinical targets disease-specific VPH technology is already being deployed in research hospitals, the grand vision of a comprehensive VPH will be possible only through a generation of radically new technologies capable of enabling a completely new approach, which is holistic and personalised, to biomedical research and clinical practice. Objective: Proposals should lay the foundations for radically new, potentially disruptive technologies for framing, building, and taming the complexity that a fully integrative approach to the human physiopathology involves. https://www.biomedtown.org/VPHFET/reception/vphfetpublicrep/roadmap

58. © 2011 VPH Institute VPH NoE & Discipulus STEP VPH Research roadmap VPH NoE annual update – 2012 vision and strategy should target personal health forecasting and in silico clinical trials Discipulus CSA – Digital Patient roadmap http://www.vph-noe.eu/news/452-vph-vision-a-strategy-paper-ii

59. © 2011 VPH Institute VPH & ITFoM VPH Institute workgroup “Systems medicine: bridging Physiome/VPH and systems biology” – Peter Hunter, Adriano Henney, Stig Omholt Meeting organised by the EC between VPH and ITFoM Two communities are developing the same vision starting from two different points Such vision cannot be fully realised without a complete integration of these two strands Virtual human technology can realise Systems medicine and Personalised Medicine

60. © 2011 VPH Institute Position on “Green paper” FET Proactive – Future and emerging technologies for the VPH (VPH-FET) E-infrastructure – VPH infostructure ICT for social Challenges – Personal Health Forecasting – In silico Clinical Trials – Digital Patient Health – Middle-out systems medicine – Personalised medicine – Health technology

61. © 2011 VPH Institute Targets for FP7 FET proactive call based on VPH-FET roadmap ICT for health call 11 2013: in silico medicine – Final VPH call with modelling and tools topics – Digital Patient based on Discipulus roadmap – CSA to roadmap in silico clinical trials – CSA to roadmap personal health forecasting Full support to IT Future of Medicine – Joint white paper on Virtual Patient – VPH Institute associate member, to ensure VPH technology is a pillar of the FET Flagship – ITFoM representatives invited to join Institute workgroup 61

62. © 2011 VPH Institute Horizon 2020 – first info Document from COM expected for November 2011 (October Inter-Service-consultation) 3 main areas: – Increasing Excellence in the Science Base – Tackling Societal Challenges – Industrial Leadership and Competitive Frameworks Rules for participation – Indirect cost: 75% (for personnel only); ERC: 25% – Funding quotas: 75% on everything or depending on type of project different quote BUT independent from type of beneficiary 62

63. © 2011 VPH Institute Targets for Horizon 2020 Increasing Excellence in the Science Base – FET: ITFoM flagship (if funded) – Health: lobby with ITFoM for a molecule-to-organism perspective in systems medicine and personalised medicine research, with massive use of VP technologies – Infra: monitor with ITFoM that Systems Biology Infrastructure makes wide space for VPH infrastructural services Industrial Leadership and Competitive Frameworks – Innovation: “missing mile” in health technology (EAMBES) Tackling Societal Challenges  Primary Lobbying target – Technologies for in silico medicine 63

64. © 2011 VPH Institute ICT for Health in Horizon 2020 ICT for societal challenges: in silico medicine – Digital Patient: VPH user interface Information and knowledge integration Targets secondary care – In silico clinical trials: VPH for population simulations Targets health industry – Personal Health forecasting: VPH on-line services processing of personal health cloud data Targets personal and primary care 64

65. © 2011 VPH Institute Thank you!