1. WELCOME CENTRAL LEPROSY TEACHING AND RESEARCH INSTITUTE, TIRUMANI,CHENGALPATTU

2. HISTORY 1924 Lady Wellington Leprosy Sanatorium at Tirumani
Managed by Church of Scotland. Dr. Paul Brand devoted his life for the reconstructive Surgery
1946
Before Independence, Mahatma Gandhi Father of our Nation visited the land of Tirumani. He gave written message of blessing to the patients of the Sanatorium and wished well to the staff.
SIGNATURE AND GREETINGS OF MAHATMA GANDHIJI
Significance of 30th January
on – Father of the Nation visited CLTRI Coincidentally, he died on
30th January every year celebrated as Anti Leprosy Day.

3. HISTORY
CLTRI was established by Government of India under a Governing Body
Dr. Dharmendra famous Leprologist was associated with CLTRI as Director from 1967 to 1971 he was Emeritus Medical Scientist of CLTRI.
Significant Contribution :- Lepromin Test
Standardization of DDS (Diamino Diphenyl Sulphone) a drug used for treating leprosy patients.
1974
CLTRI became a subordinate office of DGHS under MOH&FW
Standardization of MDT (Multi Drug Therapy ) done in this Institute.
1991
Nodal Centre for Thalidoamide drug therapy for ENL (Erythrosom Nodosum Leprosom) reaction Cases.

4. OBJECTIVE
To undertake research into basic problems relating to the occurrence and spread of leprosy and its control.
To train manpower necessary to implement NLEP.
To provide specialized services in the area of diagnosis, reaction, relapse and Reconstructive surgery in Leprosy.
To monitor and evaluate National Leprosy Eradication Programme.
Additional Responsibitiy given in 2005 after Elimination of
Leprosy
CBHI Training
RNTCP Operational Research
IDSP Training

6. AREA OF CLTRI Total Land of CLTRI - 560.83 Acres
Institutional Buildings Acres
Residential Buildings Acres
Vacant Land Acres
Land Given to HLL
(for proposed Medipark
on by MOHFW) Acres

7. BUILDING 1.HOSPITAL BLOCK : Out Patient Unit
Main Hospital -124 Bedded Hospital
Sick Room
Medical Investigation Ward
Surgical Ward with X-ray department & Operation theatre
Physiotherapy Block
MCR and Footwear Unit
Centralised Kitchen
Laundry
Centralised Stores

8. BUILDING (Continued) 2. ADMINISTRATIVE BLOCK 3. HOSTEL Administration
Laboratory & Animal House
Library
Epidemiology
3. HOSTEL
Scientist Hostel Rooms
Students Hostel Rooms
Canteen

9. STAFF STRENGTH – STATUS REPORT
Sl. No.
Group
Total Strength
Filled
Vacancy
Vacancy Percentage 1
A ( Medical)
Specialist 15 3 12
87%
GDMO 11 6 5
45% 2
A- Non Medical
100%
B- Gazetted
60% 4
B- Non-Gazetted 19 14
26%
Group C
117 84 33
28%
MTS 80 56 24
30%
TOTAL
250
165 85
34%
66 %
34 %

10. 10% reduction in Non-plan*
Budget Estimate
S.No.
HEAD
PLAN
NON-PLAN
10% reduction in Non-plan*
Balance Budget 1
Salaries
84150 2
Wages
1400 3
Overtime allowance 10 9 4
Medical Treatment
750 75
675 5
Domestic Travel Expenses
500
300 30
270 6
Office Expenses
2200
2020
202
1818 7
Publication 8
Other Administrative Expenses
250
Supplies and Materials
3500
2800
280
2520
Minor Works
1550 11
Scholarships /Stipend 12
Other charges 13
Motor Vehicles
450 45
405 14
Machinery and Equipment
1500
TOTAL
9500
92500
695
91805

11. Epidemiology & Statistics
CLTRI
Clinical
Surgical
Epidemiology & Statistics
Laboratory

12. CLINICAL Medical Record Section Nursing Section Wards
Out Patient Department
Wards
Nursing Section
Medical Record Section

13. CLINICAL (Cont.)
Expert Management of reactions with Thalidomide, Relapses/Drug Resistance etc.
Teaching activities in leprosy to Undergraduates, House Surgeons of Medical Colleges, NMS Supervisors and Nurses.
Collection and study of relapse/recurrence cases in leprosy.

14. CLINICAL (Cont.)
On Going research activity Drug Resistance Surveillance using Mouse foot Pad

15. Out-Patients particulars for the Last 5 years
(Till Oct ) 1
No. of new
Cases attended
OPD 64
104 74 90 48 2
No. of old
7155
7220
6192
6094
3353 3
No. of patients
attended OPD
from GLC block
2680
2074
1514
1694
776 4
No. of other
Cases (NCL)
Attended OPD
2224
1748
1441
1161
775 5
Total no. of
patients seen
in OPD
12123
11146
9221
9039
4952
GLC - Government Leprosy Centre
NCL - Not a Case of Leprosy

16. SURGICAL Surgical Unit Physiotherapy Section
Artificial Limbs & Footwear Section
X-ray Section
Micro-cellular Rubber

17. Surgical (cont.) The Basic functions: Reconstructive Surgery
Patient care activities.
Teaching and Training Programs.
Research.

18. Physiotherapy Section
Physiotherapy Services to PAL.
Various Teaching and Training programs.
Counselling & Health Education.
Facilities Available
Wax Bath,
Electrical Muscle Stimulator,
Inter Ferential Therapy,
Ultra Sonic Therapy
Traction Table.

19. Artificial Limbs & Footwear Section Micro-cellular Rubber
Footwear and Prosthetic to the Leprosy patients
Micro-cellular Rubber
Small Production unit - Micro-Cellular Rubber sheets (2000 sheets per annum)
Providing MCR sheets to other states

20. Details of Major and Minor Surgery Done for the Last 5 years
Surgeries
Major Surgeries –(Reconstructive Surgery) 1.
Claw finger correction 7 14 6 8 2.
Claw thumb correction 3 5 1 3.
Wrist drop Correction - 4.
Drop Foot Correction 5.
Lagapthalmos Correction 2 6.
Surgical Decomposition of
Nerves (Ulnar Nerve, Median
Nerve, Posterior Nerve) 4 7.
Amputation (Below Knee &
Below Elbow Amputation)
Minor Surgeries 8.
Ulcer Surgery 53 16 20 9.
Miscellaneous like Biopsy, MTH
Resection, Calcaneal shaving,
lagopthalmus, Skin Grafting,
Cystectomy etc. 18

21. Physiotherapy Activities for the last 5 year
S.No
Activities 1.
New Case 70 55 77 51
195 2.
Assessments
973
895
708
530
789 3.
Hand Exercises
1905
1823
1742
1755
1943 4.
Foot Exercises
857
797
737
714
749 5.
Wax Therapy
1845
1741
1698
1598
1740 6.
Splints
460
416
778
309
407 7.
General Cases 91 60 67 52 71

22. Footwear and Prosthetic Supplied for the last 5 yearNo 1.
Simple and
Modified Micro
cellar Rubber
Sandals (in pairs)
1234
1119
1199
942
500 2.
Orthotic and
Prosthetic
Appliances(in no’s) 23 21 25 28 5 3.
Major repair of
Orthosis and
Prosthesis (in no’s) 8 4 13 12 1 4.
Modifications Arch
Support and
Metatarsal Bars
(in no’s)
144
115
171 93 54

23. Division of Epidemiology & Statistics
Monitoring
& Evaluation Unit
Statistics
Electronic Data Processing Unit
Technical
Training
Library

24. Division of Epidemiology & Statistics
CLTRI Website was created by our unit.
Website for our institute was hosted in NIC server (
Logo for our Institute was designed.
Inventory Management Software was developed.
Consultancy services to the BCGVL, Guindy, Chennai for creation of website and Inventory management system.

25. Monitoring & Evaluation of NLEP Activities
Monitoring & Evaluation of NLEP Activities among
Tamil Nadu, Karnataka, Kerala and Lakshawdeep
states/UT was carried out.
Visits Made for Monitoring Activities
Lakshadweep Islands population of school children were Examined on January 2012.
Tamil Nadu, Karnataka, Pondicherry States/UT for planning M & E Activities.
M & E conducted in Erode District, Tamil Nadu.

26. Surveillance Activities
Phase I of the Activity Study of the Household and Neighbourhood Contacts of newly Reported Leprosy cases in the CLTRI OPD from Thirukalukundram Taluk area work was carried out during October 2011.
Phase II of the Activity is started on August 2012
and completed on September 2012
Analysis of the collected data is under process.

27. PROPOSALS
SFC proposal for Strengthening of CLTRI was Prepared and submitted in DGHS (17 Oct 2012).
Operational Research Study to ascertain the reasons for High Endemicity in 24 districts of 3 states (Andhra Pradesh, Gujarat, Karnataka) was send to CLD(31 May 2012).

28. Data Analysis OPD Data -New case attending CLTRI OPD for the
past 2 year were entered and analysed.
Spatial Distribution of (Geographical Information) of New cases attending CLTRI was prepared.
Monthly progressive Report from districts of Tamil Nadu, Andhra Pradesh and other states were received and entered into Computerised Simplified Information System (CSIS).
Analysis of Reaction Case data is under process.

29. Training Activities
State/District Leprosy Officer (SLO/DLO) = 3 batches
(5 days)
Medical Officer Training Course (5 days) = 2 batches
Non-Medical Health Supervisor’s (2 months) = 2 batches
Skin smear Technician Training (5 days) = 1 batch
Laboratory orientation Training (BCG Staff) = 2 batches
Final MBBS students (one day visit) =125 students
CRRI Training (5 days ) =110 Trainees
Tertiary case management of Leprosy (10 days) = 1 batch
Inplant training in Microbiology & = 1 batch
Molecular Biology to Biotechnology students

30. Library Books - 3278 Journal - 4409 Periodicals Foreign journals - 24
Indian Journals - 09

31. Workshop/Conference / Training Attended
Dr. V.C.Giri Assistant Director (Epid) attended HIVCONGRESS 2012, Held at Mumbai from 16th to 18th March 2012, Presented one Research paper and Two paper by Co-authors in scientific session.
Attended RTI Act for Public Information Officer training at ISTM, New Delhi –August 2012
Published 2 paper in International Journals.
Dr. V.C.Giri, AD (Epid) & Dr. R. Veerkumaran, CMO delivered lectures in Leprosy CMC organised by Tirunelveli Medical College, Tirunelveli, Tamil Nadu.
Mr. U. Aravindan, Statistical Investigator Gr. II attended training in Statistical Analysis system (SAS) training held at Christian Medical College, Vellore, Tamil Nadu.

32. LABORATORY Biochemistry & Animal House Sterilisation
Hematology & Immunology
Microbiology & Molecular Biology
Clinical Pathology & Histopathology
Sterilisation
Biochemistry & Animal House
LABORATORY

33. LABORATORY (cont.)
Investigation for Leprosy related and other Routine Investigations
Basic and Applied Research activities in Leprosy.
Research in field of Diagnosis, Molecular Biology, Drug therapy, Animal studies in the field of Leprosy etc.,

34. LABORATORY (cont.) On going Research projects:
Study on surveillance of Drugs [rifampicin and dapsone] resistance, among smear positive multibacillary leprosy cases
Detection of fumonisin producing Fusarium species from rice seeds by polymerase chain reaction.
Variable number tandem repeats VNTRs finger printing as an Epidemiological marker for Mycobacterium leprae haplotyping

35. Laboratory Investigations in the Last 5 yearsNo
DEPARTMENTS / SECTIONS 1
Clinical Pathology & Skin
Smear
1233
1010
831
1168
669 2
Hematology & Serology
2255
3316
3000
3767
1980 3
Microbiology
262
397
100
129 82 4
Histopathology &
Molecular biology (Routine &
Research activities)
483 71
331 5
Biochemistry
1705
3130
3244
1463 6
Animal Position in the
Animal House
1. Balb/C Mice Inbred Strain
2. Swiss Albino Mice Inbred Strain
3. Rabbit … …
4. Rat … …
5.Sheep
323
269 14
548
496

36. Scientific Publications in last 1 year
Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy. Lepr Rev. 2011 Mar;82(1):36-45.
OXA beta-lactamase-mediated carbapenem resistance in Acinetobacter baumannii. Indian Journal of Medical Microbiology, Vol. 29, No. 3, July-September, 2011, pp
Detection of Amp C genes encoding for beta-lactamases in Escherichia coli and Klebsiella pneumoniae. Indian Journal of Medical Microbiology, Vol. 30, Issue 3, 2012, pp
blaIMP AND blaVIM Mediated Carbapenem Resistance in Pseudomonas and Acinetobacter species in a Tertiary Care Hospital in India. The Journal of Infection in Developing Countries, October 2012.

37. Thank you

38. SIGNATURE AND GREETINGS OF MAHATMA GANDHIJI

39. Phase I: Phase II: 9 cluster are surveyed out of 18 clusters
2531 population was Examined
13 Cases case were found. NCDR= per 10000
Phase II:
3702 population was Examined
13 Cases case were found. NCDR= per 10000
Adult
Child
Total
Paucibacillary (PB) 6 3 9
Multibacillary (MB) 4
Adult
Child
Total
Paucibacillary (PB) 6 3 11
Multibacillary (MB) 2