We think you have liked this presentation. If you wish to download it, please recommend it to your friends in any social system. Share buttons are a little bit lower. Thank you!
Presentation is loading. Please wait.
Published byDillan Whitelaw
Modified about 1 year ago
Neonatal Physiology Tulane Pediatric Surgery
Topics Fluids and Electrolytes Cardiopulmonary Temperature Regulation Jaundice Host Defenses Surgical Stress Response
Fluids and Electrolytes Glucose –Placental –Glycogen Storage –Gluconeogenesis –Hypoglycemia SGA Surgical Pts –Hyperglycemia
Fluids and Electrolytes Calcium –Placental Diffusion 75% third trimester –Limited Stores –Renal Immaturity –Hypoparathyroidism –Citrate can bind and decrease Ca
Fluids and Electrolytes Magnesium –Associated with Calcium –Growth Retardation –Maternal Diabetes –Exchange Transfusions
Fluids and Electrolytes Blood Volume –Highest – Delivery Cord Clamping –Polycythemia Hct>65 Diabetes Toxemia SGA Partial Exchange
Fluids and Electrolytes Hemolytic Anemia –Maternal Antibodies –Direct Coombs –Rh most common –Congenital Infections –SS Dz
Fluids and Electrolytes Anemia –Premature Infants –Erythropoeitin
Fluids and Electrolytes Hemoglobin –80% Fetal –Erythropoeisis 2-3 months –P50 Adult Hgb – 27 mmHg –P50 Fetal Hgb – 8 mmHg
Jaundice Hemolysis Glucoronyl Transferase Unconjugated Hyperbilirubinemia Peaks 3 rd Day – 6-7mg/dl Resolves Day 10
Jaundice Non Physiologic –Breast Feeding –Hemolytic Disease –Hypothyroid –Pyloric Stenosis –Crigler-Najar –Extravascular Blood –Biliary Atresia –Hepatitis
Jaundice Non-Physiologic –Conjugated > 2mg/dl –Rises > 5mg/dl/day –Born Jaundiced –Doesn’t Resolve
Temperature Regulation Evaporation Conduction Convection Radiation
Temperature Regulation Humidified Environments –Incubator –Ventilator Circuits Radiant Warmers –Dry Heat –Increased insensible losses Clothes/Blankets
Temperature Regulation Hypothermia –Hypoglycemia –Vasoconstriction –Coagulopathy –Emergence from Anesthesia
Renal Function Low GFR Better at 2 weeks Normal at 1-2 years Decreased Concentrating Ability –600mOsm Insensitive to ADH
Cardiopulmonary Fetal Circulation –Right to Left Shunts Foramen Ovale Ductus Arteriosus –Hypoxemia –Hypercarbia –Acidosis
Cardiopulmonary Persistent Fetal Circulation –Sepsis –Meconium Aspiration –Congenital Diaphragmatic Hernia –Idiopathic –Treatment Ventilation Pharmacology ECMO
Cardiopulmonary Surfactant Deficiency –Premature –Alveolar Stability –Exogenous Administration
Host Defenses Cellular Immunity –WBCs Phagocytosis Adherence Killing Decreased Stores Poor Stem Cell Production
Host Defenses Immunoglobulins –IgG crosses the placenta –Poor Response to Antigen Challenge IgA and IgM No type specific Antibodies –Decreased Complement System Function –Increased Mortality with Pyogenic Bacterial Infections
Surgical Stress Response Initially Poorly Understood –Crude Monitoring –Few Outcome Studies Myths –Anesthetics – Unsafe/Not Approved –Pain –Could Anesthesia Blunt Surgical Stress Response?
Surgical Stress Response Measured Catecholamines, Insulin, Cortisol. Adult Physiology Levels Decreased when Anesthesia Administered
HYPERBILIRUBINEMIA Fatima C. Dela Cruz. Jaundice Yellowish discoloration of the skin, sclera and other mucous membranes of the body.
Transition and Stabilization of the Newborn Letha Nix RNC.
Vomiting in the Newborn Not uncommon for some vomiting in 1st few hours and days after birth Overfeeding, poor burping Overfeeding, poor burping DDx:
Developed by D. Ann Currie, RN, MSN. Physiological Responses of the Newborn to Birth Respiratory Adaptations: Mechanical changes Chemical changes Thermal.
Neonatal Jaundice Hyperbilirubinemia Fred Hill, MA, RRT.
Neonatal Assessment RC 290. Labor: 3 Stages Stage 1 : Cervical dilatation Stage 2: Birth of baby Delivery of placenta Normal time for all three stages.
The complications can be broadly classified into two categories: Immune Complications Non-immune Complications.
Ma. Luisa de Villa-Manlapaz, MD, MHPEd February 8, 2011 ASMPH.
Maternal-Child Nursing Care Optimizing Outcomes for Mothers, Children, & Families Maternal-Child Nursing Care Optimizing Outcomes for Mothers, Children,
Dr.Hisham Ahmed,M.D,MRCS.Eng Asst.Professor of General & Pediatric Surgery B.U.H2015.
Neonatal Jaundice Dezhi Mu MD/PhD Department of Pediatrics, West China Second University Hospital, Sichuan University.
ORIENTATION: 2005 Exchange Transfusion. n Exchange transfusion is indicated with the presence of hemolytic disease when bili rubin levels meet those associated.
Neonatal Endocrinology Prof Dr. Olcay Evliyaoğlu.
Adverse Effects of Blood Transfusion. Adverse Effects of Blood Transfusion ANY unfavorable consequence is considered an adverse effect of blood transfusion.
Fetal Development: Dr. Dina Nawfal Dr. Dina Nawfal Department of Obstetrics & Gynecology College of Medicine University of Mosul.
Fetal Development RC 290 The Placenta Placental Structure Purple and pancake shaped 6 inch diameter, 1 inch thick square meter surface area Attaches.
By the end of this presentation, the student should be able to: Describe bilirubin synthesis, transport, metabolism and excretion Distinguish between.
Physiology of the Newborn Respiratory Changes. Circulatory Changes Anatomic changes: Umbilical arteries and vein contract and close. Ductus arteriosus.
Neonates Dr.I.Lakshminarayana. Structure Normal new born Adaptation to extra uterine life Nutrition Maintaining temperature Common neonatal problems Neonatal.
Blood Transfusion in The Neonate Presented by R1 簡維宏.
Rafat Mosalli MD Abnormal Gestation. Objectives What is Normal gestation? What is Normal gestation? Newborn classification according to age and Weight.
Dr.Abdulaziz Alsoumali Intern Alyamamh hospital Pediatric rotation Dr.Abdulaziz Alsoumali Intern Alyamamh hospital Pediatric rotation Jaundice.
Quality Education for a Healthier Scotland Multidisciplinary Neonatal Jaundice Promoting multiprofessional education and development in Scottish maternity.
Developed by D. Ann Currie, RN, MSN. High Risk Newborn Nursing Care.
Physiological Response of Newborn to Birth Chapter 23.
Pediatric Fundamentals Prematurity Drs. Greg and Joy Loy Gordon January 2005.
High Risk Newborn Mary L. Dunlap MSN, APRN Fall 10.
Adjustments to Extrauterine Life By : Mohammad Abuadas RN, MSN.
Neonatal Jaundice Carrie Phillipi, MD, PhD. Newborn with Jaundice.
Amniotic fluid Lec. 18. Testing amniotic fluid associated with cytogeneic analysis. Amniotic fluid is a product of fetal metabolism which provide an information.
Neonatal Physiology and Anesthesia Elena Brasoveanu, MD Boston University March 2, 2006.
Neonatal Endocrinology Prof Dr. Oya Ercan. Transition to extrauterine life -Hypothermia, hypoglycemia, hypocalcemia Adrenal cortex – autonomic nervous.
This presentation is meant to guide students when rotating in the NICU. It is not to replace the recommended textbooks. Khalid Altirkawi, MD This presentation.
Post-Operative Care of Congenital Heart Disease Patients A brief pediatrics perspective.
Neonatal Jaundice Dr. Mohamed Haseen Basha Assistant professor ( Pediatrics) Faculty of Medicine Al Maarefa College of Science and Technology.
Neonatal Physiology Teka Siebenaler RRT Cardiopulmonary Services University of Minnesota Amplatz Children’s Hospital.
Lecture 8 blood bank Hemolytic Diseases: 1-Hemolytic disease of the Newborn and Fetus 2- Hemolytic anaemias Dr: Dalia Galal Hamouda.
The Infant of a Diabetic Mother Islamic University Nursing college.
Hyperbilirubinemia. Case 1 5 day old former term male infant born to a 23 y.o. G1P0->1 woman. Is exclusively breastfeeding. Has total bilirubin of 25,
Fetal development organ system develop from the 3 primary germ layers.
Physiological Problems of the Fetus and Placenta.
CONGENITAL AND ACQUIRED RESPIRATORY DISORDERS IN INFANTS.
Hyperbilirubinemia Neonatal Hyperbilirubinemia. Jaundice Yellow discoloration of skin due to elevated serum bilirubin level > 5mg/dl in neonates > 2 mg/dl.
Neonatal hyperbilirubinemia JFK pediatric core curriculum MGH Center for Global Health Pediatric Global Health Leadership Fellowship Credits: Brett Nelson,
Blood Transfusion in The Neonate Dr.Boskabadi Neonatologist.
high-risk newborn Identification of high-risk newborns The high-risk neonate :can be defined as a newborn, regardless of gestational age or birth weight,
Maternal Antibodies – Implications for the fetus/neonate BY: Nicole Stevens.
TREATMENT. Hyaline Membrane Disease Prenatal prevention and prediction –Prevent premature birth with tocolytics, antibiotics to address ongoing infection.
Rh-Blood TYPES. Rh-Blood groups: Rh-Blood groups: The Rh-factor named for the rhesus monkey because it was first studied using the blood of this animal.
JAUNDICE Just Call Me Yellow Mary Johnson RNC/MSN Gwinnett Hospital System.
© 2017 SlidePlayer.com Inc. All rights reserved.