Presentation on theme: "By Nabina Dongol Miranda Chergosky"— Presentation transcript:
1By Nabina Dongol Miranda Chergosky Hymenolepis nanaalso known asVampirolepis nanaWith Special Guest Hymenolepis diminutaByNabina DongolMiranda Chergosky
2Taxonomy Kingdom: Animalia Family: Hymenolepididae Genus: Hymenolepis Phylum:PlatyhelminthesClass:CestodaOrder:Cyclophyllidea
3Hymenolepididae Only two species of this family can infect humans. Hymenolepis nanaHymenolepis diminutaHymenolepiasis is the term when a human is infected with either H. diminuta or H. NanaHymenolepis nanaHymenolepis diminuta
4Hymenolepis nanaH. nana is commonly called the dwarf tapeworm. Nanos = dwarfH. nana is the most common tapeworm in humans worldwide.H. nana has been called Vampirolepis nana because H. diminuta has an unarmed rostellum and the rostellar hooks of H. nana were viewed as the basis for putting it in a separate genus.
5Hymenolepis diminuta Commonly called Rat tapeworm. Female rats parasitized with H. diminuta were quicker to retrieve their young than non-infected rats. The rat's fitness, or contribution to the future gene pool is increased by investing more time in its present offspring since it's future survival is not known.In humans, H. diminuta is very similar to H. nana
6Hosts of H. nana Definitive host Intermediate host (Optional) Human MiceRatsIntermediate host (Optional)FleasBeetlesThe only cestode that parasitizes humans without requiring an intermediate host.
7Hosts of H. diminuta Definitive host Intermediate host Rats Dogs HumansIntermediate hostGrain beetleLots of other arthropodsOnly when the intermediate host is ingested by the definitive host will H. diminuta mature.
8Geographical Distribution Worldwide*Frequently found intemperate zonesRates of infection for H. nana in humans.* 1% in southern United States* 34% in Argentina* 46% Sicily
9Morphology H. nana Adult worm are only 10-45 mm long and 0.5-1 mm wide Neck is long and slenderThey have segments that are wider then they are long
10Morphology H. nanaEggs generally measure between 30 to 47 microns in diameter.They are round to oval, and should contain a six-hooked oncosphere.They have polar filaments that lie between the eggshell and the oncosphere.
11Morphology H. nanaScolex bears a retractable rostellum armed with a single circle of hooks.The scolex also has four suckers.Genital pores are unilateral (side of the segment)Each mature segment contains three testes
12Morphology H. diminuta Grows to be about 20 - 60cm or more in length. Consists of up to 1000 proglottids that are approximately four times as wide as they are long.Each proglottid contains three round testes, a bi-lobed ovary, a compact vitelline gland and a large uterus opening to a lateral genital pore.The scolex has four suckers and a retractable rostellum that does not have hooks.
13Morphology H. diminutaEggs are a round or slightly oval and yellowish brown in color.Eggs are larger at µm in diameter than H. nana eggs.The oncosphere (hexacanth) has six hooks (of which at least four are visible in top photo).Can produce over 250,000 eggs per day. Which is one hundred million eggs in slightly over a year.
14MorphologyThe most characteristic morphological feature of the group is the small number of testes.The combination of few testes, usually unilateral genital pores, and a large external seminal vesicle permits easy recognition of the family.
16Life Cycle H. nanaEggs are ingested by an arthropod intermediate host where they develop into cysticercoids, which can infect humans or rodents upon ingestion.When eggs are ingested (food, water, hands) the oncospheres contained in the eggs are released. The oncospheres penetrate the intestinal villus and develop into cysticercoid larvae.Upon rupture of the villus, the cysticercoids return to the intestinal lumen, evaginate their scoleces and attach to the intestinal mucosa where they develop into adults that reside in the ileal portion of the small intestine producing gravid proglottids.
17Life Cycle H. nanaEggs are passed in the feces when released from proglottids after the proglottids disintegrate in the small intestine. An alternate mode of infection consists of internal autoinfection, where the eggs release their oncospheres, which penetrates the villus continuing the infective cycle without passage through the external environment.The life span of adult worms is 4 to 6 weeks, but internal autoinfection allows the infection to persist for years.Eggs of H. nana are immediately infective when passed with the stool and cannot survive more than 10 days in the external environment.
18Life cycle of H. diminuta Matures in about 20 days.
19How do you get infected? From H. nana….. By accidentally ingesting tapeworm eggs.by ingesting fecally contaminated foods and waterby touching your mouth with contaminated fingersby ingesting contaminated soil.Once you are infected, the dwarf tapeworm may cause auto infection where the tapeworm may reproduce inside the body and continue the infection.From H. diminuta … *Human infection results from eating such foods as dried fruits and precooked breakfast cereals in which the infected grain insects larvae are present.*Eating an intermediate host of H. diminuta.
20Pathogenesis in H. nana Light infections are asymptomatic. When large numbers of worms are present, they may give rise to abdominal pain, diarrhea, headache, and various non-specific symptoms. (This is the same for H. diminuta in humans)H. nana can be deadly in children or people with a weak immune system. The larva will burrow into the walls of the intestine and absorb all the nutrition.Dehydration can result from prolonged diarrhea.
21Diagnosis and Treatment Detection of eggs in feces.Praziquantel acts very rapidly.Expect full recovery following treatment.Seeing tapeworm in intestine.Fecal floatFecal smear H. nana
22Prevention Good hygiene Elimination of rats and mice A well-balanced diet to promote resistance to infectionPublic health and sanitation programs
25Article Questions Does H. nana need an intermediate host? No, an intermediate host is optional in H. nana.What is the common name for H. nana?dwarf tapeworm
26Article Questions Does this parasite cause death in healthy people? No. Can be deadly in children or people with a weak immune system. The larva will burrow into the walls of the intestine and absorb all the nutrition.What is it called when H. nana will re-infect the human without ever leaving the body?auto infection
27Article QuestionsHow long after the ingestion of and egg does it take to become a mature tapeworm?5 to 6 days