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口腔診斷學 陳玉昆副教授 : 高雄醫學大學 口腔病理科 07-3121101~2755 Intraoral brown, bluish and black conditions 口腔棕色、藍色、黑色疾病.

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Presentation on theme: "口腔診斷學 陳玉昆副教授 : 高雄醫學大學 口腔病理科 07-3121101~2755 Intraoral brown, bluish and black conditions 口腔棕色、藍色、黑色疾病."— Presentation transcript:

1 口腔診斷學 陳玉昆副教授 : 高雄醫學大學 口腔病理科 ~2755 Intraoral brown, bluish and black conditions 口腔棕色、藍色、黑色疾病

2 Understanding: 1. Intraoral brown, bluish and black conditions 學 習 目 標學 習 目 標

3 1.Kaohsiung Medical University, Oral Pathology Department 2.Cawson RA: Oral Diseases. 3rd Ed., pp Cawson RA: Oral Diseases. 3rd Ed., pp Cawson RA: Oral Diseases. 3rd Ed., pp AFIP (American air-force institute of pathology) References: 參考資料

4 Melanin Blood Ref. 1

5 Hairy tongue Localized pigmented Endocrine disorder Brownish, Blackish Pigmented Lesions Exogenous Endogenous

6 Melanocyte Stimulating Hormone Tyrosinase Ref. 2 Intraoral brown and black conditions

7 NormalLentigo simplex Junctional activity Compound nevus Intramucosal nevusBlue nevus Ref. 2 Intraoral brown and black conditions

8 Junctional activity Intramucosal nevus Compound nevus IntraoralCutaneous Limina propria Refs. 1, 2 Intraoral brown and black conditions

9 Epithelium Pigmented basal cell Melanophage Pigmented basal keratinocyte Refs. 1, 2 Intraoral brown and black conditions Oral Melanotic Macule

10 Amalgam Tatto Amalgam restoration Amalgam retrograde filling Refs. 1, 3 Intraoral brown and black conditions

11 Graphite Tatto Ref. 1 Intraoral brown and black conditions

12 Hairy Tongue Ref. 1 Intraoral brown and black conditions

13 Early Changes of Melanoma 1.Appear recently 2.Change in degree of pigmentation 3.Bleeding or ulceration 4.Rapid growth (in size or elevated) Refs. 1, 2

14 Melanoma Ref. 1

15 Melanoma Ref. 1

16 Melanoma Ref. 1

17 Melanoma Ref. 1

18 Melanoma Ref. 1 Immunohistochemical staining of HMB-45 (A) and S-100 (B) revealed diffuse positivity in the tumor cells.

19 Von Reclinghausen’s disease of skin multiple neurofibroma Cafa-Au-Lait-spot Ref. 5

20 Cafa-Au-Lait-spot Ref. 1

21 Addison’s Disease Pituitary Gland ACTH Gluco-cortisoid (Hydrocortisone) Blood circulation product Cause adrenal produce Into Ref. 4

22 Peutz-Jeghers Syndrome Bluish black macules Skin pigment but not oral tends fade with age Intestinal polyp Refs. 1

23 HemangiomaMucocele Eruption cystHematoma Bluish Lesions Ref. 1

24 Varicoses Ref. 1

25 Mucoepidermoid Carcinoma Ref. 1

26 Knowing how to differentiate brown, bluish & black oral conditions SUMMARY


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