2. The Madrina Fashion Show A 6 continent fashion show, challenging the top fashion students from fashion schools around the world, to create wardrobes and items that counter the hypersensitivity (allodynia) of Complex Regional Pain Syndrome (CRPS). * Other CRPS symptoms such as edema (swelling), excessive sweating, and temperature changes will also be included. However, the primary fashion design focus will be on hypersensitivity (allodynia).

3. Imagine every time you put on clothes, it felt as if an iron was pressing up against your skin? Imagine? *Sadly, you would not have to imagine this if you had CRPS.

4. Complex Regional Pain Syndrome Complex Regional Pain Syndrome (CRPS) formerly known as and still commonly referred to as Reflex Sympathetic Dystrophy (RSD), is the worlds most painful disease according to the McGill Pain Index. CRPS is when your bodys central nervous system is constantly misfiring pain signals to the brain that your body is in extreme pain, when in actuality it is not. It is not only incurable, but lacks any effective treatment, thus giving it the nickname of the Suicide Disease. Nearly 1 in 6 take their own life. The disease leaves people in 24/7 EXCRUCIATING pain with no relief. Cannot be emphasized enough just how UNBEARABLE the pain of CRPS is. There is no pain worse than CRPS. The pain is higher than amputation according to the McGill Pain Scale and this is a CONSTANT pain. Is often misdiagnosed, as it takes an average of seeing 5 different doctors before being properly diagnosed, despite early diagnosis being critical. *A short 5 minute video providing great insight into what CRPS is like. http://www.youtube.com/watch?v=Zo-xQLigqDo

5. Hypersensitivity Fashion Design The Madrina Challenge + Dr. Elliot Krane using a blowtorch to describe the feeling of clothing touching the skin among those with hypersensitivity (allodynia) in his TED talk. http://www.youtube.com/watch?v=J6--CMhcCfQ

6. Format 18 fashion design students from each continent, will each design 4 daywear (more casual) item and 1 nightwear (more formal) item. Each designer will also be required to make a 5 minute video using a smartphone camera, to talk about their thought process of creating the wardrobes and what they learned about the disease. The winner(s) will get to design the initial Madrina collection.

7. Why A Fashion Show? Because 85% of CRPS sufferers are women and it is a demographic that cares a tremendous amount about their appearance and wardrobe. This event can help reassure them that beauty is not lost with the disease. Because nobody deserves a fashion show more than people who cannot wear clothes without being in excruciating pain. 82% of people with CRPS suffer from hypersensitivity (allodynia). The slightest touch of fabric touching the skin causes extreme pain. Because 78% of those with CRPS suffer from depression, 50% have suicide ideations, and 15% take their own life, giving it the highest suicide rate of any other disease. What they wear, how they look, and how they feel about themselves contributes to that depression. A fashion show will help combat that. *Statistics taken from 2009 RSDSA study http://tinyurl.com/qgv8mkl

8. Benefitting Portion of the proceeds go to the Nerve Injury Lab http://tinyurl.com/lkul6nfhttp://tinyurl.com/lkul6nf at Massachusetts General Hospital Hospital is ranked 2 nd among all hospitals in the U.S. http://tinyurl.com/nkn7qw5http://tinyurl.com/nkn7qw5 Is the teaching hospital of Harvard University

9. Location Broad Street Ballroom 41 Broad Street NY, NY 10004 646-624-2524 http://www.broadstreetballroom.com/ Floor Plan: http://www.broadstreetballroom.com/pdf/FloorPlan.pdfhttp://www.broadstreetballroom.com/pdf/FloorPlan.pdf

10. Goals To raise funds for CRPS research and clinical trials in finding a cure and better treatments. To increase CRPS awareness on a global scale, by challenging the top fashion students from fashion schools all over the world, to create wardrobes and items that counter the hypersensitivity (allodynia) of CRPS, while changing how the world thinks about clothing. To provide a unifying, flagship, signature fundraising event to strengthen the global CRPS community and encourage more global collaboration among CRPS sufferers, organizations, and researchers.

11. Event Details Date: Saturday, June 28 th 2014 Time: 7pm-11pm Tickets: $100 Event Description: Emerging fashion designers from top fashion schools around the world, are challenged to create wardrobes and items that counter the hypersensitivity of Complex Regional Pain Syndrome. Portion of proceeds go to benefit the Nerve Injury Lab at Massachusetts General Hospital.

12. (Madrina) CRPS CRPS

13. 1.5 *, - ( : CRPS, ) - (1Casual, 1Formal) - - ( ) 2. 5 - (2014.6.28), -

14. 1 3,000 ( ) Madrina (2014.fall ) CRPS ( ) co-work

15. http://madrinafashionshow.com https://www.facebook.com/pages/Madrina-Fashion- Show/157726787757512https://www.facebook.com/pages/Madrina-Fashion- Show/157726787757512 https://twitter.com/MadrinaFashion CRPS (Password: madrina) https://www.surveymonkey.com/sr_pass.aspx?sm=Gbw5hsuyQ7BG8ANTP4N DQF%2bILW9HDUdjfbV9oSJmMuo%3d CRPS ( ) http://www.rsds.org/pdfsall/SharmaA_AgarwalS_BroatchJ.pdf