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Hirofumi Tanaka, Ph.D. Cardiovascular Aging Research Laboratory Department of Kinesiology & Health Education The University of Texas at Austin Ischemic.

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Presentation on theme: "Hirofumi Tanaka, Ph.D. Cardiovascular Aging Research Laboratory Department of Kinesiology & Health Education The University of Texas at Austin Ischemic."— Presentation transcript:

1 Hirofumi Tanaka, Ph.D. Cardiovascular Aging Research Laboratory Department of Kinesiology & Health Education The University of Texas at Austin Ischemic Pre-Conditioning and Athletic Performance

2 Athletes and Competitive Advantage

3 Ergogenic Aids Compression Sleeves Eye Black Nasal Strip Oxygen Inhalation

4 Ischemic Preconditioning Endothelial function Resistance to hypoxic injury Ischemic tolerance

5 Olympic Marathon Gold 2:06:32 Silver 2:07:16 Bronze 2:10:00 0.5% 2.7% 270 yard 0.7 mile

6 Usain Bolt in Beijing Olympics Gold 9.69 Silver 9.89 Bronze % 2.3%

7 Treatment Effects and Measurement Variabilities

8 Different Perspective

9 Ischemic Preconditioning and VO 2 max De Groot et al. Eur J Appl Physiol Young healthy well-trained subjects

10 Ischemic Preconditioning and VO 2 max De Groot et al. Eur J Appl Physiol ± ±6.2 3%

11 Ischemic Preconditioning and Endurance Crisafulli et al. J Appl Physiol Young healthy trained men RIP: Ischemic preconditioning at rest EIP: Ischemic preconditioning after 5-min exercise (larger metabolic load)

12 Ischemic Preconditioning and VO 2 max Crisafulli et al. J Appl Physiol. 2011

13 Ischemic Preconditioning and 5 km Running Trial Bailey et al. Med Sci Sports Exerc ±2.4 min 22.0±1.9 min 2.5% Young healthy trained men 4 x 5-min 220 mmHg bilateral leg occlusion

14 Ischemic Preconditioning and VO 2 max Bailey et al. Med Sci Sports Exerc VO 2 max (ml/kg/min)

15 Ischemic Preconditioning and 100m Swimming Performance Jean-St-Michel et al. Med Sci Sports Exerc ± ± sec or 1% Canadian national- level swimmers (13-27 years) IPC, min warm- up, time trial

16 Michael Phelps vs. Milorad Cavic in 100m Butterfly Gold Silver th % 2.5%

17 Michael Phelps -18 Olympic Gold Medals-

18 Wingate Anaerobic Power Test

19 Peak power output Average power output (anaerobic capacity) Fatigue Index = (Peak - End) Peak Wingate Anaerobic Power Test

20 Remote IPC Wingate Tests 65 Rest Time (min) Experimental Protocol

21 Wingate Anaerobic Power Test

22 * Peak Power Output

23 Average Power Output

24 Fatigue Index

25 Ischemic preconditioning appears to be an effective ergogenic aid to enhance both anaerobic and aerobic athletic performance. The effects of ischemic preconditioning on maximal aerobic fitness remain controversial. The application of ischemic preconditioning to athletes is a promising area that requires more investigations. Conclusions

26

27 Ischemic Preconditioning and 5km Running Trial Bailey et al. Med Sci Sports Exerc. 2012

28 Infarct size is expressed as a % of area at risk. The black bar - mice perfused with dialysate from control subjects (n = 4). The white bar - mice perfused with dialysate from elite swimmers (n = 9). Jean-St-Michel et al. Med Sci Sports Exerc RIPC on Infarction Size in Mouse Hearts

29 Pasdois et al. J Am Heart Assoc Ischemic Preconditioning on Phosphagens


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