1. Date of download: 7/1/2016 Copyright © The American College of Cardiology. All rights reserved. From: Health-Related Quality of Life After Carotid Stenting Versus Carotid Endarterectomy: Results From CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) J Am Coll Cardiol. 2011;58(15):1557-1565. doi:10.1016/j.jacc.2011.05.054 Completeness of Data Available health status data for patients randomly assigned to carotid artery stent (CAS) versus carotid endarterectomy (CEA). Percentages listed above each bar indicate the proportion of surviving patients with health status scores available at that timepoint. Red area of bar indicates eligible with data; green area of bar indicates eligible with no data. Figure Legend:

2. Date of download: 7/1/2016 Copyright © The American College of Cardiology. All rights reserved. From: Health-Related Quality of Life After Carotid Stenting Versus Carotid Endarterectomy: Results From CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) J Am Coll Cardiol. 2011;58(15):1557-1565. doi:10.1016/j.jacc.2011.05.054 Generic Health Status During Follow-Up Trend in Medical Outcomes Study Short-Form 36 (SF-36) scores from baseline to 1 year. Higher scores indicate better quality of life; significant differences in scores (p ≤ 0.01) were noted in 5 of 8 subscales and the physical component summary scale at the 2-week follow-up visit, and in 3 of 8 subscales and the physical component summary scale at the 1-month follow-up visit. All differences between groups had resolved by 1 year. Plotted values at each timepoint represent least-squares means and associated 95% confidence intervals derived from the analysis of covariance. CAS = red; CEA = blue. Abbreviations as in Figure 1. Figure Legend:

3. Date of download: 7/1/2016 Copyright © The American College of Cardiology. All rights reserved. From: Health-Related Quality of Life After Carotid Stenting Versus Carotid Endarterectomy: Results From CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) J Am Coll Cardiol. 2011;58(15):1557-1565. doi:10.1016/j.jacc.2011.05.054 Disease-Specific Functional Limitations Trend in modified Likert scores from baseline to 1 year for (A) difficulty eating or swallowing, (B) difficulty walking, and (C) difficulty driving. Green = mild difficulty; yellow = moderate difficulty, red = severe difficulty, and black = unable. Abbreviations as in Figure 1. Figure Legend:

4. Date of download: 7/1/2016 Copyright © The American College of Cardiology. All rights reserved. From: Health-Related Quality of Life After Carotid Stenting Versus Carotid Endarterectomy: Results From CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) J Am Coll Cardiol. 2011;58(15):1557-1565. doi:10.1016/j.jacc.2011.05.054 Disease-Specific Pain Scales Trend in modified Likert scores from baseline to 1 year for (A) headaches, (B) neck pain, and (C) leg pain. Green = “a little bit,” yellow = “moderately,” red = “quite a bit,” and black = “extremely.” Abbreviations as in Figure 1. Figure Legend: