1. Date of download: 5/29/2016 Copyright © The American College of Cardiology. All rights reserved. From: Renal Denervation in Moderate Treatment-Resistant Hypertension J Am Coll Cardiol. 2013;62(20):1880-1886. doi:10.1016/j.jacc.2013.06.023 Blood Pressure and Heart Rate Changes According to Response Criteria Absolute change in blood pressure (solid bars) and heart rate (open bars) at 6 months according to response criteria. Office systolic blood pressure reduction of ≥10 mm Hg at 6 months after renal denervation (RDN) is defined as response; office heart rate reduction of ≥2 beats per minute at 6 months after RDN is defined as response. HR = heart rate; other abbreviations as in Figure 2. Figure Legend:

2. Date of download: 5/29/2016 Copyright © The American College of Cardiology. All rights reserved. From: Renal Denervation in Moderate Treatment-Resistant Hypertension J Am Coll Cardiol. 2013;62(20):1880-1886. doi:10.1016/j.jacc.2013.06.023 Effect of Renal Denervation on Office Heart Rate Office heart rate at baseline and follow-up. Values are means ± SD. Figure Legend:

3. Date of download: 5/29/2016 Copyright © The American College of Cardiology. All rights reserved. From: Renal Denervation in Moderate Treatment-Resistant Hypertension J Am Coll Cardiol. 2013;62(20):1880-1886. doi:10.1016/j.jacc.2013.06.023 Blood Pressure Changes in Patients With Available Ambulatory Blood Pressure Monitoring Before and After Renal Denervation Absolute change in office systolic (open bars) and diastolic (solid bars) blood pressure and 24-h ambulatory systolic (open bars) and diastolic (solid bars) blood pressure in patients with available ambulatory blood pressure monitoring (ABPM) before and after renal denervation (n = 36). Values are means ± SD. p values are comparisons with baseline values. Abbreviations as in Figure 2. Figure Legend:

4. Date of download: 5/29/2016 Copyright © The American College of Cardiology. All rights reserved. From: Renal Denervation in Moderate Treatment-Resistant Hypertension J Am Coll Cardiol. 2013;62(20):1880-1886. doi:10.1016/j.jacc.2013.06.023 Blood Pressure Changes in All Patients Absolute change in office systolic (open bars) and diastolic (solid bars) blood pressure in all patients (n = 54) after renal denervation. Mean ± SD. p values are comparisons with baseline values. DBP = diastolic blood pressure; SBP = systolic blood pressure. Figure Legend:

5. Date of download: 5/29/2016 Copyright © The American College of Cardiology. All rights reserved. From: Renal Denervation in Moderate Treatment-Resistant Hypertension J Am Coll Cardiol. 2013;62(20):1880-1886. doi:10.1016/j.jacc.2013.06.023 Effect of Renal Denervation on Office Blood Pressure (A) Office systolic blood pressure at baseline and at 3 and 6 months after RDN. (B) Office diastolic blood pressure (BP) at baseline and at 3 and 6 months after RDN. Values are mean ± SD. RDN = renal denervation. Figure Legend: