1. Objectives: To provide the student with knowledge of the pathogenesis, morphology, laboratory diagnosis, identification, pathology, and clinical features of medically important parasitic and viral diseases and the basic concepts of immunizing procedure against these diseases. Lecture title Introduction. Intestinal protozoa (Amoeba, Balantidium, Giardia, Chilomastix) Haemoflagellates: Leshmania spp.; Trypanosome spp. Sporozoa: Malarial parasites of human; Toxoplasma. Helminthes: Classification, Flukes: Hepatic flukes, Blood flukes (Schistosoma spp).Tap worms: Taenia spp., Echinococcus (Hydatid cyst).Nematods: Ascaris, Entrobius. Virology: Introduction, Comparison between viruses and bacteria and other microbes; Classification of viruses; Replication; Chemotherapy; Herpes viridae; Orthomyxo viruses; Paramyxo viruses; Retro viruses; Hepato viruses; Oncogenic viruses.

2. Parasitology Lectures 2014--2015 the Lecturer: Assist Prof.Dr Hadi Rasool Hassan References : 1: Markell and Voges, medical parasitology 9th edition edited by David T. John and William A. petri Jr. 2:Davidson`s principles and practical of medicine, edeted by John Macleod 40th edition 3-. Beaver & R.C. Jung. Animal Agents and Vectors of Human Disease. 5th.Ed. P.C 4:Hegner and Engemann invertbrate zoology, 2 nd edition.

3. Parasitology : The science which studying the relationship between different two kinds of organism.The smallest is a parasite all most invertebrate and the host which a bigger all most vertebrate. This science consist of three branches: 1-Medical protozology which studying the unicellular parasite Ex. Entamoeba histolytica. 2-Medical Helmenthology which studying the parasitic flat and round worms Ex. Fasciola hepatica, Ascaris lumbricodis. 3-Medical Entomology which studying the medical Erythropodes Ex. Mosquito, Ticks

4. The reationship between organism 1:Symbiosis: (living together) the relationship between two individuals depend one to other and it can't live without the other, Ex. Termied and Hyper flagellate. 2: Commensalism :(eating at the same table) the relationship between two individuals the first take or obtains the food or habitat or both from the another without causes any damage in it Ex. Entamoeba coli in human. 3: Parasitism: (eating at the table of others) the relationship between two individual the first (parasite)obtain the food or habitat or both. from the another (host ) and must be causes damage in it, Ex. Entamoeba histolytica in human. The parasites can divided to two groups: 1:Ectoparasite consist of the parasitic groups which infested on host skin or external parts of the host body Ex. mosquito, pediculous, ticks which causes infestation 2:Endoparasite consist of the parasitic groups infected internal parts of the body Ex. Giardia lamblia, Plasmodum spp., Leishmania spp. which causes infection.

5. The types of parasitism: 1: Facultative parasite: the parasite which can living in his life cycle as a parasitic or as free living Ex. Strongyloides stracularis, Crysoma buziana. 2:Obligtory parasite: this group must be living as a parasitic in all his life cycle or part of it and we can divided it to: A:Temporory obligatory parasite this parasites are visit the host between time to time and obtains food or take Blood meal of it Ex. Mosquito. B: Sporadic obligatory parasite this parasite living in part of his life cycle as a parasitic on the external parts of the body host and in second part of his life cycle free living Ex. Ticks, mites. C: Permanent obligatory parasite : this parasitic group must be living all his life cycle as a parasitic on or in the hosts, Ex. Pediculous, Entamoeba histolytica. Plasmodium spp. Zoonosis diseases consist of the veterinary diseases which transport between vertebrate animals only.Ex. Theileria. Zoonotic diseases consist of common diseases which infected human and animals Ex. Hydated cyst

6. Type of hosts 1: (final,definitive, primay ) the host infected with adult stage or sexual phase of parasite which produce eggs or larvae Ex. human infected with Ascaris, Ancylostoma. 2: Intermediate or secondary host : the host infected with larval stage or asexual phase of parasite and must be important or essential to complete the life cycle of parasite, Ex. Herbivorous animals infected with hydated cyst. 3:Accidantal host :the host ordinary infected with larval stage of parasite but it is not essential to complete it's life cycle, Ex. Human infected with Hydated cyst. 4: Reserver host: the host infected with larval stage but without symptoms and it important as a source of infection Ex. dogs infected with Leishmania. 5:Vector host: the invertbrate host which transport the infected stage of parasite from the host to another and it can be divided to biological vector like mosquito or mechanical vector house fly.

7. Major categories of classification Kingdom, Phylum Family, Order Class, Genouse, Species,.

8. 1 – Protozoa : Unicellular parasite contains one or more nuclei in troph & four or more cystic stage motile by means of locomotion or nonmotile, production by binary fission or chizogony can produced by sexual process. The protozoa classified to four classes depend on locomotion organulla. A – Sarcodyna ( Amoeba )is related to two stages :Trophozoit & cyst through it`s life cycle. The troph can live inside the host and multiplies with in it. In the external environment the troph will transform in to cyst. The mode of locomotion occurs due to a presence of pseudo podia. The mode of reproductive is by binary fission.The main parasite with clinically important as following : Entamoeba hystolytia Entamoeba coli Entamoeba gingivalis Endolimax nana Dientamoeba frgalis lodamoeba butchlii Acanthamoeba spp. Neagleria fowleri

9. B-.Mastigophora (Flagellata ) 1 - Intestinal flagellate : The movement occurs due to presence of flagella the No. of flagella differs from one to other.The mode of production binary fission. In life cycle of it is troph and cyst. The main spp. : - Giardia lamblia - Trichomonas hominis - Chilomastix mesneli 2 - Blood flagellate( Haemo flagellata ).Leishmania spp...Trypanasoma spp.. 3- Atrial flagellate :.Trichomonas vaginalis in the vagina.Trichomonas tinex in the mouth

10. C - Ciliata Only one species is medically important. [Balantidium coli ), in this class movement occurred due to presence of cilia, the mode of production is binary fission or conjugation in the life cycle, there is a troph & cyst D - Sporozoa The mode of production is by schizogony. Non motile, Need more than one host, Sexual & asexual cycle can be occurres due to the live cycle The main spp. Are: -Plasmodium spp. (malaria ) -Toxoplasma gondii - Sarcocystis hominis -Cryptosporidium parvum -Babesia microti

11. 2-Worms The worms /metazoa are multi cellular parasite. Large in size and contain many stages in their life cycle. Ther are three classes of helminthes: A- Termatoda The worm of trematoda is leaf like structure contains 2 suckers,oral and ventral suckers reproductive system present in a same worm. eccept Schistosoma spp.. Life cycle of them are: eggs,multiple larvae and adult.The larval stage are : -Meracidium -Sporocyct -Redia -Cercaria -Metacercaria Each larval stage may need host for development, in trematoda many host should be present for complete his life cycle. The main spp, -Faciola hepatica Liver flukes - Clonorchis sinensis = = - Fasciolapsis buski Intestinal flukes -Hetcrophyes heterophys = = -Paragonimus westermani Lung flukes -Schistosoma spp. Blood fluks

12. B – Cestoda (tapeworm ) Cestoda : contains head,neck and segments, the head is called scolex and the segments called proglottides.There are 3 types of proglottides : immature,mature.gravid. Male and female reproductive system. are present in same worm. So it called Hermaphrodite. There are 3 stages in their life cycle :egg, larva and adult,same of them need more than host, main species : Taenia solium Taenia saginata Diphyllobothrium latum Echinococcus spp.. Hymenolepis nana Hymolepis diminata Dipylidium caninum

13. C - Nematoda The worm of nematode differ from others two classes in the sex separated in two worm`s. ♀ & ♂. So fertilization occurs after meeting. There are: eggs,larvae & adult.The worm May needs two or more host according to it's life cycle.. Some spp. don't put eggs after meeting instead larva is molted directly.

14. The main spp. : Nematodes ( Round worms) -Enterobius vermicularis -Ascaris lumbricoides -Ancylostoma duodenale -Trichuris tricura -Trichirella spiralis - Strongyloides stracularis -Filaria worms Wecheraria bancrofti Loa loa Onchocercus vulvulous Dracanculous medinansis

15. Arthro poda It consist some groups of insect which infested on human and animal and it consider as a vectors host to another parasite as a vector to plasmodium. The important medical insects are : mosquito, pediculous, Glossinia spp., Tritomid spp., Phlebotomas spp., Zenopselos spp.. And some Erythropodes like Ticks, Mites