1. Chapter 18 Bipolar Mood Disorder

2. Definition 1.Bipolar I disorder # disorder in which at least one manic or mixed episode has occurred # commonly accompanied by at least 1 MDE but not required for diagnosis 2. Bipolar II disorder # disorder in which there is at least 1 MDE and 1 hypomanic episode # no past manic or mixed episodes. Epidemiology 1.Prevalence: 0.6- 0.9%; M:F = 1:1 2.Age of onset: teen to 20s 3.Risk factors Slight increase in upper socioeconomic groups 60-65% of bipolar patients have family history of major mood disorders

3. Classifications 1. Classifications of bipolar disorder invilves describing the current or most recent mood episodes as either manic, hypomanic, mixed or depressed 2. The current or most recent episode can be further clasiffied as without psychotic features, with psychotic features, with catatonic features, with postpartum onset, with seasonal pattern, with rapid cycling

4. Treatment 1.Biological: mood stabilizers, anticonvulsants, antipsychotics, antidepressents, ECT 2.Psychological: supportive or psychodynamic psychotherapy, cognitive or behavioural therapy 3.Social: vocational rehabitation, leave of absence from school/work, drug and EtOH cessation, substitute decision maker for finances, sleep hygiene, social skills training, education for family members.

5. Course and Prognosis of bipolar disorder 1.High suicide rate (15% mortality from suicide) 2.Relapsing and remitting course with alternating manic and depressive episodes; depressive symptoms tend to occur more frequently and last longer than manic episodes 3.May switch rapidly between depression and mania without any period of euthymia in between 4.High recurrence rate for mania – 90% will have a subsequent episode in the next 5 years 5.Rapid cycling subtype: 4 or more mood episodes in 12 months

6. The End