Presentation is loading. Please wait.

Presentation is loading. Please wait.

HISTOLOGY OF ESOPHAGUS &gastro esophageal junction

Similar presentations


Presentation on theme: "HISTOLOGY OF ESOPHAGUS &gastro esophageal junction"— Presentation transcript:

1 HISTOLOGY OF ESOPHAGUS &gastro esophageal junction
By Dr. Sobia Ibrahim Assistant Professor Anatomy, KEMU

2 ESOPHAGUS Is muscular tube Extends from pharynx to stomach
Wall has four layers: Mucosa Epithelium Lamina propria Muscularis interna or muscularis mucosae Submucosa Muscularis externa Adventitia / Serosa

3

4 UPPER 1/3 OF ESOPHAGUS MUCOSA SUB-MUCOSA MUSCULARIS EXTERNA ADVENTITIA
Epithelium: Stratified squamous non-keratinized Lamina propria: scattered lymphocytes, few lymphatic nodules, mucous glands, blood vessels Muscularis mucosae: Thick, smooth muscles longitudinally arranged SUB-MUCOSA Collagen & elastic fibres, mucous glands, blood vessels, nerves MUSCULARIS EXTERNA Skeletal (striated) muscles ADVENTITIA Collagen & elastic fibers, blood vessels

5

6

7

8 MIDDLE 1/3 OF ESOPHAGUS MUCOSA
Epithelium: stratified squamos non- keratinized Lamina propria: : scattered lymphocytes, few lymphatic nodules, mucous glands, blood vessels Muscularis mucosae: thick, smooth muscles longitudinally arranged SUB-MUCOSA Collagen & elastic fibres, mucous glands, blood vessels, nerves MUSCULARIS EXTERNA Skeletal (striated) muscles, Smooth muscles ADVENTITIA Collagen & elastic fibers, blood & lymphatic vessels

9

10 LOWER 1/3 OF ESOPHAGUS MUCOSA Epithelium: Simple columnar
Lamina propria: scattered lymphocytes, few lymphatic nodules, mucous glands, blood vessels Muscularis mucosae: thick, smooth muscles longitudinally arranged SUB-MUCOSA Collagen & elastic fibres, mucous glands, blood vessels, nerves MUSCULARIS EXTERNA Smooth muscles ADVENTITIA/ SEROSA Collagen & elastic fibers, blood & lymphatic vessels

11 GASTROESOPHAGEAL REFLUX DISEASE
It is associated with incompetent barriers at this junction; caused by hiatal hernia, decrease in lower esophageal sphincter tone. Results in reflux esophagitis as mucosal barriers are not sufficient to protect esophagus from acids, pepsin & bile causing heart burns/atypical chest pain

12 BARRETT’S ESOPHAGUS Reflux of gastric contents throu lower esophageal sphincter Gastric acid in esophagus Heart burn With time, metaplasia of epithelium (protective) Barrett’s esophagus High risk for carcinoma

13 STOMACH PARTS OF STOMACH Rugae Three histological zones Cardia Fundus
Body Pylorus Rugae Three histological zones

14 CARDIOESOPHAGEAL JUNCTION

15 Esophageal cardiac junction

16 MUCOSA: 1:Epithelium changes from: Startified squamous non keratinised into simple columnar. 2: Lamina propria: esophageal cardiac glands but in stomach (cardiac, fundic and pyloric glands). They are tubular and deep. 3:Muscularis mucosae: thick longitudinal in esophagus but thin and two layered in stomach. Submucosa: esophageal glands proper disappear. No glands in submucosa of stomach. Muscularis externa: three layered in stomach an additional oblique layer is there

17

18

19 GASTROESOPHAGEAL REFLUX DISEASE
It is associated with incompetent barriers at this junction; caused by hiatal hernia, decrease in lower esophageal sphincter tone. Results in reflux esophagitis as mucosal barriers are not sufficient to protect esophagus from acids, pepsin & bile causing heart burns/atypical chest pain


Download ppt "HISTOLOGY OF ESOPHAGUS &gastro esophageal junction"

Similar presentations


Ads by Google