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HIV genome map This genetic map of the HIV-1 viral genome depicts the

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Presentation on theme: "HIV genome map This genetic map of the HIV-1 viral genome depicts the"— Presentation transcript:

1 HIV genome map This genetic map of the HIV-1 viral genome depicts the
structural and regulatory genes in their relative position as well as their products and functions. - The remaining genes (vif, vpr, vpu, rev and nef) are regulatory genes whose products play critical roles in controlling viral expression of viral gene products within the infected cell. -The rev-responsive element (RRE) is the binding site for the rev gene product which transport RNA massage from the nucleus

2 HIV-1 and related Retroviruses
Primate lentiviruses

3 There are three major species of African green monkeys
Studies of the African green monkey and their related simian virus (SIVagm)yield important information in our understanding of HIV-1 and HIV-2. There are three major species of African green monkeys

4 Geographic domain of African green monkeys
This map of Africa indicates the native locations of different species of the African green monkey.Within each species, a unique family of SIVagm has been show to exist. Geographic domain of African green monkeys

5 Phylogenic differences of SIVagm
When the SIVagm from different species of African green monkeys are genetically mapped the phylogenic tree demonstrates unique clustering of SIVagm based on the species was obtained. Phylogenic differences of SIVagm

6 Subgroups of SIV SIVagm has several subspecies bas on the species
of African green monkey Subgroups of SIV


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