1. Bellwork Copy and complete the following Venn Diagram ReplicationTranscription

2. Science Fact of the Day The largest octopus is the Enteroctopus dofleini, also known as the giant Pacific octopus or North Pacific giant octopus. It has a 16 ft arm span and weighs about 110 pounds. As requested by Victoria Westbrook

3. CO: I will understand and explain the process and purpose of translation. LO: I will write notes about translation. I will play a BINGO using a codon chart.

4. Central Dogma DNA Nucleus Ribosome Translation Transcription Protein RNA Copy and label the:

5. Transcription Review and Translation Intro.

6. Remember our analogy from yesterday…. DNA = master copy of building plans RNA= blueprint for one room of building Protein= actual bricks that make up the building Nucleus = boss’ office Ribosome = assembly line (where the bricks are laid and a wall is built)

7. The decoding of an mRNA message into a polypeptide chain is known as translation. Proteins are assembled on a ribosome – OUTSIDE of the nucleus (in the cytoplasm)

8. Steps of Translation (Overview) 1.mRNA travels to the ribosome 2.Transfer RNA (tRNA) brings the right amino acid to the ribosome 3.A polypeptide (protein) is formed

9. How does tRNA “know” what amino acid to bring?

10. The genetic code (mRNA) is read three bases at a time. Each three-letter “word” is known as a codon. tRNA “looks” for the codon that pairs with its 3 nucleotide sequence (called an anticodon). When it connects the ribosome attaches the amino acid that tRNA was carrying to the polypeptide chain

11. ORDER MATTERS! Order of DNA bases  order of RNA bases  order of amino acids  what protein is made tRNA mRNA Amino acid

12. How to use the Codon Chart: 1.Use the left side to find the first letter in the codon 2.Use the top to find the second letter in the codon 3.Use the right side to find the third letter of the codon 4.Go to where ALL three overlap on the chart

14. How to use the Codon Wheel: 1.Begin in the middle with the first letter of the codon 2.Go outward to the second letter in the codon 3.Go outward again to the third letter in the codon.

15. Did you notice?: The codon “AUG” can specify methionine or serve as the “start” codon for protein synthesis.

16. What codon will tell the ribosome to quit putting amino acids together? What letters code for this?

17. Codon Bingo! Directions For Playing: If a codon (example: AAG) is called out, you must find the amino acid. If an amino acid (example: serine) is called out, you must find the codon. Hint! When finding a codon, there may be more than one answer…you can count all possible answers on your card!