1. NA-MIC National Alliance for Medical Image Computing http://na-mic.org The NA-MIC Kit: ITK, VTK, Pipelines, Grids and 3D Slicer as An Open Platform for the Medical Image Computing Community Steve Pieper 1,5, Bill Lorensen 2,5, Will Schroeder 3,5, Ron Kikinis 4,5 1) Isomics, Inc. 2) GE Corporate R&D 3) Kitware, Inc. 4) Brigham and Women's Hospital, Surgical Planning Lab 5) National Alliance for Medical Image Computing

2. National Alliance for Medical Image Computing http://na-mic.org Overview National Alliance for Medical Image Computing (NA-MIC) is an NIH National Center for Biomedical Computing (NCBC) The NA-MIC Kit is a Collection of Software and Methodology to Support Image Computing Innovation and Reproducibility Builds on Existing Efforts

3. National Alliance for Medical Image Computing http://na-mic.org NA-MIC Sites Leadership: –BWH: Ron Kikinis, (Overall PI) –Steve Wong Core 1 Algorithms –Utah: Ross Whitaker (Core 1 PI) –MIT: Eric Grimson –UNC: Guido Gerig –MGH: Bruce Fischl, Dave Kennedy –GaTech: Allen Tannenbaum Core 2 Engineering –GE: Bill Lorensen (Core 2 PI) –Kitware: Will Schroeder –Isomics: Steve Pieper –UCSD: Mark Ellisman –UCLA: Art Toga Core 3 DBP –BWH: Martha Shenton –Dartmouth: Andy Saykin –UCI: Steve Potkin –UofT: Jim Kennedy Core 4 Service –Kitware: Will Schroeder Core 5 Training –MGH: Randy Gollub Core 6 Dissemination –Isomics: Steve Pieper, Tina Kapur Core 7 Management –BWH: Steve Wong

4. National Alliance for Medical Image Computing http://na-mic.org NIH NCBC Goals http://grants1.nih.gov/grants/guide/rfa-files/RFA- RM-04-003.htmlhttp://grants1.nih.gov/grants/guide/rfa-files/RFA- RM-04-003.html …NIH does have goals for software dissemination… …software should be freely available… …permit the commercialization of enhanced or customized versions… …include the ability of researchers outside the center and its collaborating projects to modify the source code and to share modifications…

5. National Alliance for Medical Image Computing http://na-mic.org Role of NA-MIC Kit Analogy NA-MIC, as a Taxpayer Funded Activity is Like a Public Road System –Provides Infrastructure for a Variety of Uses –Driveways can Lead to Anything a Coop Grocery Store a Factory a Park a Gated Community

6. National Alliance for Medical Image Computing http://na-mic.org Translational Medicine Platform Industry GPL NA-MIC Kit Research Only

7. National Alliance for Medical Image Computing http://na-mic.org NA-MIC Kit Licensing Policies Technology Base for Research and Commercialization –Okay to build GPL or Closed SW on top of NA-MIC Kit –But no GPL or Closed SW in NA-MIC Kit NA-MIC Provides “Reference Standard Distribution” –Maintain Official Releases –Avoid Code Forking, Non-Free Code Creeping into Core No “Knowing” Addition of Patented Techniques into NA- MIC Kit Copyright to Substantive Works Remains with Creators –Available under NA-MIC Approved Licenses for Distribution with Kit –Insight Journal is Example of this Process

8. National Alliance for Medical Image Computing http://na-mic.org NA-MIC Kit is… Open Source Software Targeted for Medical Image Analysis and Data Management Distributed Under BSD-style License Supporting Documentation and Training for End- Users and Developers NA-MIC Development/Testing Methodology Ongoing Maintenance through NIH NCBC Conduit for Technology to Flow from Algorithm Developers to Clinicians

9. National Alliance for Medical Image Computing http://na-mic.org NA-MIC Kit Functionality First Driving Biological Project –Schizophrenia Research Quantify Structural and Functional Relationships to Disease and Symptoms Integrated Software Tools –Morphometric MRI, DTI, and fMRI –Segmentation and Registration Kit will Evolve with New DBPs and Community Uses

10. National Alliance for Medical Image Computing http://na-mic.org NA-MIC Kit Components Software Engineering Tools –CMake, Dart, CTest Image Analysis, Visualization, and GUI libraries –ITK, VTK, KWWidgets End User Application –3D Slicer Large Scale Data Processing Tools –LONI Pipeline, GRID tools http://www.na-mic.org/Wiki/index.php/SoftwareInventory

11. National Alliance for Medical Image Computing http://na-mic.org NA-MIC Kit Architecture User Desktop AlgorithmsITKVTK Slicer Modules VTK Apps Using ITK Scripts of Slicer Mods Batch Programs Non-NAMIC Cmd tools LONI Pipeline BIRN Grid Data/Compute Slicer 3.0

12. National Alliance for Medical Image Computing http://na-mic.org Development Methodology 6 months 4 months 2 months ReleasePatchNightlyContinuous Release X.Y Release X.Y.1 Release X.Y.2 Release X.Y.3 Extreme lifecycle Private Sandbox NA-MIC Sandbox Slicer ITK Dashboard CMake CTest CPack Testing

13. National Alliance for Medical Image Computing http://na-mic.org Dissemination and Training National and International Events –MIT, MGH, UNC, EPFL, NIH, UNM, UCSD… All Materials on Wiki Project Weeks –Full Week Each Summer –½ Week at Winter AHM Workshops –MICCAI 2005, 2006 –Others Planned

14. National Alliance for Medical Image Computing http://na-mic.org Practical Implications NA-MIC Kit is Available Now –Ready-Made Infrastructure for Medical Image Computing Development NA-MIC Kit is Usable –Many Examples, Tutorials, Mailing Lists… NA-MIC Kit Will Continue to Improve –Multi-Year NIH Effort and Community of Users

15. National Alliance for Medical Image Computing http://na-mic.org More Information Project Overview http://www.na-mic.org Day-to-Day Organization, Project Plans, Event Information, Reference Materials, etc, etc. http://wiki.na-mic.org